Formylated phloroglucinols from Eucalyptus loxophleba foliage |
| |
| Authors: | Sidana Jasmeen Singh Sukhvinder Arora Sunil Kumar Foley William J Singh Inder Pal |
| |
| Institution: | aDepartment of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, S.A.S. Nagar, Punjab-160062, India;bMolecular Immunology Laboratory, Department of Immunopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India;cResearch School of Biology, The Australian National University, Canberra 0200, Australia |
| |
| Abstract: | Two new naturally occurring formylated phloroglucinol compounds (FPCs), a dimer, loxophlebal B (10) and a cyclized FPC, loxophlebene (8) together with eight other formylated phloroglucinols (1–7 and 9) were isolated from the chloroform-methanol (8:2) extract of the leaves of Eucalyptus loxophleba ssp. lissophloia. The structures of new compounds were established by comprehensive spectral analysis and by comparison of their NMR data with those of related compounds in the literature. All the isolated compounds were evaluated for anti-leishmanial activity against promastigotes of Leishmania donovani. |
| |
| Keywords: | Eucalyptus loxophleba Formylated phloroglucinols Loxophlebal A Grandinal Euglobals Antileishmanial |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
