Experimental infection model for Taenia solium cysticercosis in swine. Cysticercosis Working Group in Peru |
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| Authors: | Verástegui M González A Gilman R H Gavidia C Falcón N Bernal T Garcia H H |
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| Institution: | Department of Pathology and Department of Microbiology, Universidad Peruana Cayetano Heredia, PO Box 5045, Lima, Peru. |
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| Abstract: | A novel method for infecting pigs with Taenia solium using an intramuscular innoculum of oncospheres was investigated in a series of five experiments in 18 animals. The model is simple to perform, requires a minimal number of oncospheres, permits multiple infections per animal, and decreases the variation inherent in oral infection models. This intramuscular oncosphere assay (IMOA) may provide a valuable tool to evaluate therapeutic agents or potential vaccines for cysticercosis. |
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