代谢组学在动物育种中的应用现状与前景展望

代谢组学是一门新兴的学科，与基因组学、蛋白质组学等共同构成系统生物学。近年来，代谢组学发展迅速，并在疾病诊断、生物医药研发、食品营养与科学、药理毒理学、环境科学、植物科学以及动物育种等众多领域均有应用。系统介绍了动物育种中小分子代谢物在遗传参数估计、品种（系）鉴定、重要经济性状鉴定、多组学关联分析以及动物疾病模型制备中的应用及最新研究进展，分析代谢组学研究中存在的问题。随着其研究方法的不断完善和优化，越来越多代谢物被人们所了解认识，在农用动物育种中代谢组学技术的研究逐渐增多，代谢组学必将成为动物育种的一种有力手段。

Applications and Prospects of Metabonomics in Animal Breeding

Metabolomics is a newly developed subject， which constitutes systems biology together with genomics and proteomics. In recent years， metabolomics has developed rapidly and has applications in many fields such as disease diagnosis， pharmaceutical research， food and nutrition science， toxicology， environmental science， botany and animal breeding. This paper systematically introduced the latest research progress of small molecular metabolites in animal breeding in genetic parameter estimation， breed （line） identification， identification of important economic traits， multi-omics association analysis， animal disease models， and analyzed the difficulties in metabolomics research. With the continuous improvement and optimization of research methods， more and more metabolites were understanded， meanwhile the research on metabonomics technology in agricultural animal breeding was gradually increasing and metabolomics research would surely become a powerful means of animal breeding.