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QUANTIFICATION OF CEREBRAL VENTRICULAR VOLUME IN ENGLISH BULLDOGS
Authors:Charles H.  Vite  DVM   Erik K.  Insko  PhD  MD   Helena M.  Schotland  MD   Karen  Panckeri  BA   Joan C.  Hendricks  PhD  VMD
Affiliation:University of Pennsylvania, Department of Clinical Studies;School of Veterinary Medicine, Metabolic Magnetic Resonance Research;Computing Center, School of Medicine.
Abstract:Quantitative measurement of cerebral ventricle volume of eight English bulldogs was performed using magnetic resonance (MR) imaging. The mean ventricular volume was 14.8 ml. with a range of 8.6 m1.-38.1 ml. The mean ventricular volume of two beagles was 2.2 ml with a range of 0.7 m1.3.7 ml. The percent of intracranial volume occupied by ventricle was found to be significantly larger in bulldogs (14.0%; S.D. = 7.9%) than in beagles (Range = 1.048%). The relationship between the percent of intracranial volume occupied by ventricle and measurements of body weight, age, sex, and various measures of skull anatomy of the bulldog was also determined. The relationship between ventricular volume and neurologic dysfunction was examined. There was a possible trend between high percent of intracranial volume occupied by ventricle and low body weight. This study will serve as a pilot study for examining the relationship between ventricular volume and neurologic disease in bulldogs.
Keywords:bulldog    hydrocephalus    ventricular volume    brain volume    magnetic resonance imaging
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