QUANTIFICATION OF CEREBRAL VENTRICULAR VOLUME IN ENGLISH BULLDOGS |
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Authors: | Charles H. Vite DVM Erik K. Insko PhD MD Helena M. Schotland MD Karen Panckeri BA Joan C. Hendricks PhD VMD |
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Affiliation: | University of Pennsylvania, Department of Clinical Studies;School of Veterinary Medicine, Metabolic Magnetic Resonance Research;Computing Center, School of Medicine. |
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Abstract: | Quantitative measurement of cerebral ventricle volume of eight English bulldogs was performed using magnetic resonance (MR) imaging. The mean ventricular volume was 14.8 ml. with a range of 8.6 m1.-38.1 ml. The mean ventricular volume of two beagles was 2.2 ml with a range of 0.7 m1.3.7 ml. The percent of intracranial volume occupied by ventricle was found to be significantly larger in bulldogs (14.0%; S.D. = 7.9%) than in beagles (Range = 1.048%). The relationship between the percent of intracranial volume occupied by ventricle and measurements of body weight, age, sex, and various measures of skull anatomy of the bulldog was also determined. The relationship between ventricular volume and neurologic dysfunction was examined. There was a possible trend between high percent of intracranial volume occupied by ventricle and low body weight. This study will serve as a pilot study for examining the relationship between ventricular volume and neurologic disease in bulldogs. |
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Keywords: | bulldog hydrocephalus ventricular volume brain volume magnetic resonance imaging |
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