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Disseminated candidiasis secondary to fungal and bacterial peritonitis in a young dog
Authors:Catherine L Rogers  DVM  DACVECC  ; Christopher Gibson  VMD  ; Susan L Mitchell  DVM  DACVS  ; John H Keating  DVM  DACVP  and Elizabeth A Rozanski  DVM  DACVIM  DACVECC
Institution:Departments of Clinical Sciences, and Biomedical Sciences, North Grafton, MA 02130;, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 02130
Abstract:Objective – To describe a severe case of bacterial sepsis and disseminated candidiasis in a previously healthy dog.
Case Summary – Fungal sepsis was identified in a 2-year-old dog following intestinal dehiscence 4 days after abdominal surgery. Septic peritonitis was identified at admission and evidence of dehiscence at the previous enterotomy site was found during an exploratory laparotomy. Both gram-positive cocci and Candida albicans were cultured from the abdominal cavity. Candida sp. was also subsequently cultured from a central venous catheter. Euthanasia was performed due to failure to respond to therapy. Fungal organisms, morphologically consistent with Candida spp., were found in the lungs and kidney on postmortem histopathologic examination indicating disseminated candidiasis.
New or Unique Information Provided – Candida peritonitis is a well-recognized entity in humans and contributes to morbidity and mortality in critically ill patients. Abdominal surgery, intestinal perforation, presence of central venous catheters, and administration of broad-spectrum antibiotics are all considered to be suspected risk factors. This report describes the first known case of systemic candidiasis occurring secondary to Candida peritonitis and bacterial sepsis in a critically ill dog.
Keywords:candidiasis  critical care  opportunistic infection  surgical wound dehiscence
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