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Changes of myocardial glycogen content and right ventricular function in hypoxia swimming rats |
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| Authors: | ZHOU Xiao-mei MA Ning ZHU Long-kun QI Bao-shen |
| Institution: | 1.Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School Basic Medicine, Peking Union Medical College, Beijing 100005, China;2.Fujian Medical University, Fuzhou 350004, China |
| Abstract: | AIM: To investigate the changes of myocardium glycogen content and the relation ship between changes of the myocardial glycogen content and the myocardial function. METHODS: Male Wistar rats were placed in (hypoxia rats) and made to swim in (hypoxia swimming rats) a hypobaxic chamber simulating an altitude of 5 000 m above sea level. The content of myocardium glycogens was determined by colorimetry. RESULTS: The myocardium glycogen content of rats significantly reduced along with the prolongation of hypoxic exposure and approached to control level in hypoxia swimming rats. The myocardial function of right ventricule was improved significantly compared with control group.CONCLUSION: Moderate exercise (swimming) is beneficial to hypoxic adaptation of rats under the condition of chronic hypoxia. |
| Keywords: | Anoxia Myocardium Glycogen Ventricular function right on |
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