Changes of PGE2, PGI2 and TXA2 concentration in rat traumatic pulpitis |
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| Authors: | PAN Jian-bo HUANG Shi-guang WANG Hua-dong HU Chao-feng YAN Liang |
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| Institution: | 1. Department of Stomatology, Guangzhou Second Municipal Hospital, Guangzhou 510150, China;
2. Department of Stomatology, Medical College of Jinan University, Guangzhou 510632, China;
3. Department of Pathophysiology, Medical College of Jinan University, Guangzhou 510632, China |
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| Abstract: | AIM: To study the relationship between prostaglandins and acute pulpitis. METHODS: Rat traumatic pulpitis model was established by pulp exposure. The kinetic pathological changes in dental pulpal tissues and changes of PGE2,6-Keto-PGF1α and TXB2 concentration in dental pulp were observed. RESULTS: After pulpal trauma, the dental pulp showed inflammatory changes and the concentrations of PGE2,6-Keto-PGF1α and TXB2 were increased, which peaked at 6 hour post-trauma. CONCLUSION: Prostaglandins play a significant role in the pathogenesis of pulpitis. |
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| Keywords: | Pulpitis Thromboxane A2 Prostaglandins E Prostaglandins I |
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