穴位埋线对运动性疲劳大鼠能量代谢水平的影响

本试验旨在探讨埋线疗法对运动疲劳的改善作用。以运动性疲劳大鼠为研究对象，将36只SD大鼠随机分为空白组、跑台组、埋线组，每组12只，埋线组进行相应穴位埋线，研究其对骨骼肌能量代谢水平的影响。采用7周递增跑台训练法构建运动疲劳模型。7周训练结束后，除空白组外，跑台组、埋线组进行大速度力竭运动，记录力竭时间，测定能量代谢相关指标及疲劳相关生物标志物，制作骨骼肌切片。研究结果表明，与空白组相比，跑台组、埋线组血糖、糖原含量均显著降低（P<0.05），乳酸、尿素氮、丙二醛含量均显著升高（P<0.05），骨骼肌切片光镜下均观察到病理损伤现象。埋线组ATP含量、ATP酶活性均显著高于跑台组（P<0.05），肌酸激酶含量上升幅度低于跑台组。综上所述，穴位埋线可以使机体具有更多的能源物质、更少的代谢产物，并可能通过改善氧化应激、提高能量供应等调节机体能量代谢水平，延缓运动疲劳的产生。

Thread-embedding Therapy for Regulating Energy Metabolism in Exercise-induced Fatigue

The purpose of this trial was to explore the effect of thread-embedding therapy on exercise-induced fatigue.The exercise-induced fatigue rats were taken as the research object.36 SD rats were randomly divided into blank group,model group and treatment group,with 12 rats in each group.Thread-embedding therapy was performed on the treatment group before training,to study thread-embedding therapy for regulating energy metabolism in exercise-induced fatigue.After a 7-week training,except for the blank group,the exercise groups performed high-speed exhaustion exercises.The exercise time,energy metabolism-related indicators and fatigue-related biomarkers were measured and skeletal muscle sections were made.The results showed that compared with control group,the blood glucose and glycogen contents of the exercise groups were significantly reduced(P<0.05),and the contents of lactic acid,urea nitrogen and malondialdehyde were significantly increased(P<0.05).Pathological damage was observed under light microscopy of skeletal muscle sections.The ATP content and ATPase activity of the treatment group were significantly higher than those of the model group(P<0.05),and the increase in creatine kinase content was lower than that of the model group.In summary,these results indicated that thread-embedding therapy made the body have more energy substances and fewer metabolites,and might regulate the body’s energy metabolism level by improving oxidative stress and increasing energy supply,and delay the generation of exercise-induced fatigue.