| 双波长紫外分光光度法测定复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素的含量 |
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| 引用本文： | 仲晓宁,张璇,巩相莲.双波长紫外分光光度法测定复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素的含量[J].中国兽药杂志,2005,39(9):26-28. |
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| 作者姓名： | 仲晓宁 张璇 巩相莲 |
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| 作者单位： | 1. 烟台市畜牧检测中心,山东,烟台,264003
2. 烟台市林源兽药有限公司,山东,烟台,264000 |
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| 摘 要： | 建立了复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素含量的检测方法.采用双波长紫外分光光度法,直接测定两组分的含量.结果显示可同时测出复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素的各自含量,且吸收度与各自的浓度成良好线性关系.恩诺沙星平均回收率为100.1%,RSD为0.04%(n=5).盐酸多西环素平均回收率为100.2%,RSD为0.14%(n=5).本方法简便、快速、可靠,可用于复方恩诺沙星可溶性粉的含量测定.
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| 关 键 词： | 双波长紫外分光光度法 恩诺沙星 盐酸多西环素 |
| 文章编号： | 1002-1280（2005）09-0026-03 |
| 收稿时间： | 2005-04-13 |
| 修稿时间： | 2005年4月13日 |
Determination of enrofloxacin and doxycycline hyclate in the compound enrofloxacin soluble powder by dual-wavelength ultraviolet spectrophotometry |
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| ZHONG Xiao-ning,ZHANG Xuan,GONG Xiang-lian.Determination of enrofloxacin and doxycycline hyclate in the compound enrofloxacin soluble powder by dual-wavelength ultraviolet spectrophotometry[J].Chinese Journal of Veterinary Drug,2005,39(9):26-28. |
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| Authors: | ZHONG Xiao-ning ZHANG Xuan GONG Xiang-lian |
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| Abstract: | A dual-wavelength ultraviolet spectrophotometry for determination of enrofloxacin and doxycycline hyclate in compound enrofloxacin soluble powder is established. The relationship between the absorbance and the concentration of enrofloxacin and doxycycline hyclate is linear. The average recovery for enrofloxacin was 100.1% , RSD =0.04% ; and the average recovery for doxycycline hyclate was 100.2%, RSD =0.14%. The method is simple, quick and reliable, and has been proved to be a good practice for determination of enrofloxacin and doxycycline hyclate in compound enrofloxacin soluble powder. |
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| Keywords: | dual-wavelength ultraviolet spectrophotometry enrofloxacin doxycycline hyclate |
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