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| 猪口蹄疫O型灭活疫苗PD50效检攻毒方式探索 | |
| 引用本文： | 郎洪武,闫岩,张荣军,肖怀红,杨汉春.猪口蹄疫O型灭活疫苗PD50效检攻毒方式探索[J].中国兽药杂志,2004,38(3):26-27. |
| 作者姓名： | 郎洪武 闫岩 张荣军 肖怀红 杨汉春 |
| 作者单位： | 1. 中国兽医药品监察所,北京,100081 2. 中牧股份兰州生物药厂,甘肃兰州,730046 3. 中国农业大学,北京,100094 |
| 摘 要： | 用10 000 TCID50的OR/80株F13细胞毒或用10 000 LD50的OR/80株乳鼠组织毒(ORMF8),通过肌肉注射途径、蹄踵球部或趾间皮内注射途径接种O型口蹄疫抗体阴性架子猪进行攻毒试验,三种途径均不能使试验猪产生规律性发病. |
| 关 键 词： | 猪口蹄疫O型灭活疫苗 攻毒试验 |
| 文章编号： | 1002-1280(2004)03-0026-02 |
| 修稿时间： | 2003年6月30日 |
Studies on the challenge manners for potency testing of FMD type O swine vaccine |
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| LANG Hong-wu,YAN yan,ZHANG Rong-jun,XIAO Huai-hong,YANG Han-chun.Studies on the challenge manners for potency testing of FMD type O swine vaccine[J].Chinese Journal of Veterinary Drug,2004,38(3):26-27. | |
| Authors: | LANG Hong-wu YAN yan ZHANG Rong-jun XIAO Huai-hong YANG Han-chun |
| Institution: | LANG Hong-wu~1,YAN yan~2,ZHANG Rong-jun~2,XIAO Huai-hong~2,YANG Han-chun~3 |
| Abstract: | Challenge testing were taken by three ways of intramuscular injection, intradermal injection into the heel bulbs of one foot or into the space of two toes with 10 000 TCID_(50) of OR/80F_(13) cell virus. The results showed that three ways could not make the pigs appear orderliness representative FMD infectious disease symptoms and pathological changes. Another challenge testing were taken by the same three ways with 10 000 LD_(50) of OR/80F_8 (ORMF_8) organnismic virus. The results showed that three ways also could not make the pigs appear orderliness representative FMD infectious disease symptoms and pathological changes. |
| Keywords: | FMD type O inactivated swine vaccine challenge testing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |