| 乙型肝炎与戊型肝炎病毒重叠感染者血清HBV标记物结果分析 |
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| 引用本文： | 何姗,龙尧,庞超,胡南. 乙型肝炎与戊型肝炎病毒重叠感染者血清HBV标记物结果分析[J]. 湛江医学院学报, 1998, 0(Z1) |
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| 作者姓名： | 何姗 龙尧 庞超 胡南 |
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| 作者单位： | 广东医学院附属医院感染内科 |
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| 摘 要： | 目的：观察乙型肝炎病毒（ＨＢＶ）与戊型肝炎病毒（ＨＥＶ）重叠感染对ＨＢＶ复制的影响。方法：以血清ＨＢｓＡｇ和抗ＨＥＶ均阳性患者３６例作为重叠组，以单纯ＨＢＶ感染患者３６例作为对照组。两组病例抗ＨＡＶ－ＩｇＭ和抗ＨＣＶ均为阴性。采用ＥＬＩＳＡ法测定两组的ＨＢＶ－Ｍ。结果：重叠组血清ＨＢｅＡｇ的阳性率明显低于对照组（Ｐ＜０．００１），抗ＨＢｅ阳性率明显高于对照组（Ｐ＜０．０５）。结论：ＨＢＶ与ＨＥＶ重叠感染后，ＨＢＶ的复制受到一定程度的抑制
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| 关 键 词： | 乙型肝炎病毒；戊型肝炎病毒；重叠感染；抑制 |
Analysis of results of serum HBV markers in patients with HBV and HEV superinfection |
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| He Shan,Long Yao,Pang Chao,et al. Analysis of results of serum HBV markers in patients with HBV and HEV superinfection[J]. Journal of Guangdong Medical College, 1998, 0(Z1) |
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| Authors: | He Shan Long Yao Pang Chao et al |
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| Abstract: | Objective:To study the effects of HBV and HEV superinfection on HBV replication.Methods:36 cases with positive HBsAg and antibody to hepatitis E virus were defined as superinfection group.36 cases with only HBV infection were defined as control group.IgM antibody to hepatitis A virus and antibody to hepatitis C virus were negative in the two groups.HBV markers and anti HEV were detected by ELISA.Results:The positive rates of serum HBeAg in the superinfection group were significantly lower than in the control group( P <0.001)and those of anti HBe were significantly higher( P <0.05).Conclusion:HBV replications are partially inhibited when HBV is superinfected by HEV. |
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| Keywords: | hepatitis B virus hepatitis E virus superinfection inhibition |
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