|
|||||
|
|
Antispasmodic effects of Persea cordata bark fractions on guinea pig ileum |
|
| Authors: | Cechinel-Filho Valdir Zampirolo Júlio A Stulzer Hellen K Schlemper Valfredo |
| Affiliation: | 1. Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)/CCS, Universidade do Vale do Itajaí (UNIVALI), 88302-202, Itajaí, SC, Brazil;2. Department of Biological and Health Sciences, Universidade do Planalto Catarinense (UNIPLAC), Lages, SC, Brazil;3. Department of Morphophysiology, Centro Agroveterinário (CAV), Universidade para o Desenvolvimento do Estado de Santa Catarina (UDESC), Lages, SC, Brazil |
| Abstract: | The present study describes the antispasmodic activity of some fractions from the bark of Persea cordata, against guinea pig ileum contracted by acetylcholine and histamine. Hexane and dichloromethane fractions demonstrated the most promising biological effects, having similar potency to that of papaverine, a well-known antispasmodic agent. |
| Keywords: | Persea cordata Antispasmodic activity Guinea pig ileum |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |