Effect of Semecarpus anacardium nut milk extract on rat serum alpha-fetoprotein level in aflatoxin B1-mediated hepatocellular carcinoma |
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| Affiliation: | 2. Biocruces Bizkaia Health Research Institute, Barakaldo, Spain;3. Department of Clinical Analysis, Galdakao-Usansolo Hospital, Osakidetza Basque Health Service, Barrio Labeaga, Galdakao, Spain;4. Department of Pathology, Galdakao-Usansolo Hospital, Osakidetza Basque Health Service, Barrio Labeaga, Galdakao, Spain;5. Department of Radiology, Galdakao-Usansolo Hospital, Osakidetza Basque Health Service, Barrio Labeaga, Galdakao, Spain;1. Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;2. School of Pharmacy, Fudan University, Shanghai 201203, China;3. Department of Otorhinolaryngology, Changhai Hospital, Shanghai 200433, China;4. Department of Diving Medicine, Faculty of Navy Medicine, Second Military Medical University, Shanghai 200433, China;5. Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China;1. Department of Immunology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran;2. Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran |
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| Abstract: | ![]()
An increased level of serum alpha-fetoprotein is observed in aflatoxin B1 (AFB1)-induced hepatocellular carcinoma (HC) in rats. Semecarpus anacardium nut milk extract (200 mg/kg, p.o., for 14 days) significantly reduced serum alpha-fetoprotein levels within the normal range, suggesting an antitumour activity against AFB1-induced HC. |
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