Anti-inflammatory activity of Butea frondosa leaves |
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| Institution: | 1. Department of Chemistry, GC University, Faisalabad, Pakistan;2. Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan;3. Department of App. Sci. and Hum., Faculty of Engg. and Tech., Mody Institute of Technology and Science (Deemed University), Lakshmangargh, 332311 Sikar, Raj., India;1. Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan;2. Department of Chemistry, University of Gujrat, Rawalpindi Sub-campus, Satellite Town, Rawalpindi, Pakistan;3. Department of Chemistry, Abbottabad University of Science and Technology, Havelian, Abbottabad, Pakistan;4. School of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, United Kingdom;5. Department of Biochemistry, Computational Medicinal Chemistry Laboratory, UCSS, Abdul Wali Khan University, Mardan, Pakistan;6. Department of Chemistry, University of Paderborn, 33098, Paderborn, Germany;7. Department of Chemistry, University of Otago, P.O. Box 56, Dunedin, 9054, New Zealand;8. Department de Química, Universitat de les Illes Balears, Crta. de Valldemossa km 7.5, 07122, Palma de Mallorca (Baleares), Spain;1. Institute of Quality Standards and Testing Technology for Agro-Products, Key Laboratory of Agro-Product Quality and Safety, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-Food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, China;2. School of Materials Science and Engineering, Beijing Institute of Fashion Technology, Beijing 100029, China;1. Department of Pharmacology, JSPM''s Jayawantrao Sawant College of Pharmacy and Research, University of Pune, Hadapasar, Pune-411028, India;2. Haffkine Biopharmaceutical Corporation Ltd., Pimpri, Pune-411018, India |
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| Abstract: | In the carrageenan-induced rat paw oedema, the aqueous extract of Butea frondosa leaves showed dose-dependent (25–100 mg/kg, p.o.) anti-inflammatory activity which at the highest dose was almost comparable to ibuprofen (25 mg/kg, p.o.).The LD50 was higher than 5 g/kg, p.o. in rats. |
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