Abstract: | Three 25- to 30-kg adult mongrel dogs had nonsurgical experimentally induced unilateral renal artery perforations produced by a rotating guide wire tip. The guide wire was introduced via a percutaneous femoral artery puncture. Baseline arteriograms were compared with serial postperforation arteriograms made over a three-month peirod, and the natural history and healing rate of these lesions were assessed. In the three-dog study, the renal artery perforations were self-limiting. The dogs'healing processes alone seemed adequate in preserving both renal and renal artery function. |