| 玫瑰花中抗补体活性成分研究 |
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| 引用本文： | 杨庆雄,张万全,余天华,孙黔云.玫瑰花中抗补体活性成分研究[J].安徽农业科学,2011,39(26):15962-15964. |
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| 作者姓名： | 杨庆雄 张万全 余天华 孙黔云 |
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| 作者单位： | 贵州师范大学化学与材料科学学院,贵州贵阳,550001;贵州师范大学生命科学学院,贵州贵阳,550001;中国科学院天然产物化学重点实验室,贵州贵阳,550002 |
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| 基金项目： | 国家自然科学基金项目(30860038); 贵州省科技厅科技基金项目(黔科合J字[2009]2090号); 国家重大基础研究(973计划)前期研究专项(2007CB516813) |
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| 摘 要： | 目的]分离鉴定玫瑰（Rosa rugosa）花中的抗补体活性成分。方法]在活性筛选指导下,并用多种色谱方法进行分离纯化,并用核磁共振、质谱数据与文献数据对比鉴定化合物结构。结果]从活性部位中分离出3个黄酮类化合物,分别为木犀草素（1）、槲皮素（2）和山柰酚（3）。结论]玫瑰花提取物有体外抗补体作用,其中黄酮类化合物是其活性成分。
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| 关 键 词： | 玫瑰花 抗补体活性 木犀草素 槲皮素 山奈酚 |
Study on Anticomplement Activity of Extracts from Flowers of Rosa rugosa |
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| YANG Qing-xiong et al.Study on Anticomplement Activity of Extracts from Flowers of Rosa rugosa[J].Journal of Anhui Agricultural Sciences,2011,39(26):15962-15964. |
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| Authors: | YANG Qing-xiong |
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| Institution: | YANG Qing-xiong et al(College of Chemistry and Material Science,Guizhou Normal University,Guiyang,Guizhou 550001) |
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| Abstract: | Objective] The aim was to isolate and identify the anticomplement constituents in the flowers of Rosa rugosa.Method] Under the guidance of activity screening,many chromatographic processes were used to isolate and purify,moreover,structures of compounds were identified through comparing nuclear magnetic resonance(NMR) and mass spectrometric data(MS) with literature data.Result] Three kinds of flavonoids compounds were isolated from active sites,and they were identified as luteolin(1),quercetin(2) and kae... |
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| Keywords: | Flowers of Rosa rugosa Anticomplementary Luteolin Quercetin Kaempferol |
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