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Progress in signal transduction of erythropoietin |
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| Authors: | XIAO Yu-long ZHAI Zhen-yan YUAN Wei-jie |
| Institution: | Department of Nephrology, Changhai Hospital, Shanghai 200433, China |
| Abstract: | Erythropoietin is a critical growth factor in development of erythrocyte. After binding to its receptor, eryhropoietin produces biological action through consequent activation of intracellular signal transduction systems, including JAK2-STAT5, sos-Ras-MAPK, IRS-2-PI3-K+ and Ca2+ channel. |
| Keywords: | Erythropoietin Signal transduction Receptors erythropoietin |
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