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Mast cell tryptase and asthma
Authors:NIU Qing-xia  HE Shao-heng
Institution:Allergy and Inf lammation Research Institute, Shantou University Medical College, Shantou 515031, China
Abstract:As an important mediator of allergic inflammation, mast cell tryptase is involved in the in duction of hypersensitivity, infiltration of inflammatory cel s and t issue remodeling in respiratory tract.The effects of tryptase inhibitors on the actions of tryptase show further the potential of tryptase in the pathogenesis of asthma and its inhibitors in the treatment of asthma.
Keywords:Asthma  Tryptase  Serine proteinases  Mast cells  
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