The roles of IL - 17, 18, 23, 25 in the allergic diseases |
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Authors: | XIE Hua HE Shao-heng |
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Institution: | Allergy and Inflammation Research Institute, The Medical Collegeof Shantou University,Shantou 515031, China |
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Abstract: | Many nnewly discovered interleukins have been implicated to play an important role in the pathogenesis of the allergic diseases, for example, human interleukin (IL)-17, a T-cell derived cytokine; interleukin (IL)-18, an interferon (IFN)-gamma-inducing cytokine; interleukin (IL)-23, produced by activated dendritic cells, and interleukin (IL)-25, a recently described T helper 2 (Th2) cell-derived cytokine. Understanding their characteristic and roles in diseases may help us to know better the mechanism of the allergic diseases and develop the strategy for treating the disease. |
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Keywords: | Interleukin-17 Interleukin-18 Interleukin-23 Interleukin-25 Allergic diseases |
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