心肌缺血后处理对急性ST段抬高型心肌梗死再灌注心律失常的影响

目的探讨缺血后处理对STEMI心肌再灌注心律失常的影响.方法 2006年10月—2009年1月在北华大学附属医院心内科住院的STEMI患者且于12 h内行直接PCI者共64例,随机分为两组：对照组（34例）和缺血后处理组（30例）.对照组给予单纯再灌注治疗,缺血后处理组采用再灌注30 s/再缺30 s,交替3次后再持续灌注的方法.对比观察再灌注心律失常的发生频率.结果与对照组相比,缺血后处理组再灌注心律失常的发生率显著减少.结论急性心肌缺血后处理能够显著减少再灌注心律失常的发生.

Effects of Ischemic Postconditioning on Reperfusion Arrhythmia of ST-Segment Elevation Acute Myocardial Infarction

Objective To study postconditioning effects on reperfusion in STEMI patients undergoing emergency percutaneous coronary intervention（PCI） for the myocardial reperfusion Arrhythmia.Method From Oct.2006 to Jan.2009 at Affiliated Hospital of Beihua University,64 patients with STEMI undergoing emergency percutaneous transluminal coronary angioplasty（PTCA） were randomly divided into two groups：the control group（n=34） without any intervention after PTCA,and the experimental group（n=30） were treated by ischemic postconditioning by 3 episodes of 30-seconds inflation and 30-seconds deflation of the angioplasty balloon.Two groups were observed and compared in the incidence of reperfusion arrhythmias.Results In the postconditioning group, the incidence of reperfusion arrhythmias significantly reduced.Conclusion The postconditioning in emergency PCI can significantly reduce the incidence STEMI myocardium reperfusion arrhythmias.