| 北陆花青素的抗氧化作用 |
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| 引用本文： | 王荣姣,李昭华,黄红林,陈少云,董先智.北陆花青素的抗氧化作用[J].安徽农业科学,2011,39(12):7061-7063. |
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| 作者姓名： | 王荣姣 李昭华 黄红林 陈少云 董先智 |
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| 作者单位： | 王荣姣(南华大学药物药理研究所,湖南衡阳,421001;中国科学院生物物理研究所,北京,100101);李昭华,董先智(中国科学院生物物理研究所,北京,100101);黄红林(南华大学药物药理研究所,湖南衡阳,421001);陈少云(晨星越橘科技发展有限公司,辽宁丹东,118000) |
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| 基金项目： | 国家星火计划，中国科学院研发实验服务基地测试基金 |
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| 摘 要： | 目的]探讨北陆花青素的抗氧化作用。方法]分别采用Fenton反应体系、邻苯三酚自氧化体系、亚油酸体系和普鲁士蓝法来测定北陆花青素对OH.和O2-.的清除作用、对脂质过氧化物的抑制作用及其还原能力进行评价,并以维生素C和葡萄籽花青素作为阳性对照。结果]北陆花青素的抗氧化能力高于葡萄籽花青素和维生素C,对OH.和O2-.具有很强的清除作用,其IC50分别为0.345mg/ml和34.28μg/ml,对脂质过氧化物有明显的抑制作用并有较高的还原能力。结论]北陆花青素是一种潜在的具有抗氧化活性的天然药物。
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| 关 键 词： | 北陆（Northland） 花青素 自由基 抗氧化 |
Antioxidative Activity of Anthocyanins from Northland |
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| WANG Rong-jiao et al.Antioxidative Activity of Anthocyanins from Northland[J].Journal of Anhui Agricultural Sciences,2011,39(12):7061-7063. |
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| Authors: | WANG Rong-jiao |
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| Institution: | WANG Rong-jiao et al(Institute of Pharmacy and Pharmacology,University of South China,Hengyang,Hunan 421001) |
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| Abstract: | Objective] To explore antioxidative activity of anthocyanins from Northland.Method] Using anthocyanins from grape seeds and vitamin C as positive control,Fenton reacting system,pyrogallol autoxidation system,linoleic acid system and Prussian blue method were respectively employed to determine OH· scavenging activity,O2-·scavenging activity,inhibitive effect on lipid peroxidation and reducing capacity of anthocyanins from Northland.Result] Antioxidative activity of anthocyanins from Northland was higher than that in anthocyanins from grape seeds and vitamin C.Anthocyanins from Northland had strong scavenging activities on OH· and O2-·,IC50 of which was 0.345 mg/ml and 34.28 μg/ml,respectively.Furthermore,it was also provided with obvious inhibiting activity on lipid peroxidation and reducing capacity.Conclusion] Anthocyanins from Northland may be a potential natural medicine with antioxidative activity. |
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| Keywords: | Northland Anthocyanins Free radical Antioxidation |
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