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| 甘蔗汁对大鼠酒精性肝损伤的保护作用 | |
| 引用本文： | 韦日明,王凌宇,肖胜军,彭新青,肖福英,夏春波,吴群英,蒋林彬,刘健翔. 甘蔗汁对大鼠酒精性肝损伤的保护作用[J]. 安徽农业科学, 2011, 39(6): 3606+3661-3606,3661 |
| 作者姓名： | 韦日明 王凌宇 肖胜军 彭新青 肖福英 夏春波 吴群英 蒋林彬 刘健翔 |
| 作者单位： | 1. 桂林医学院细胞与遗传学教研室,广西桂林,541004 2. 桂林医学院病理学教研室,广西桂林,541004 3. 桂林医学院生物技术教研室,广西桂林,541004 4. 桂林医学院解剖学教研室,广西桂林,541004 |
| 摘 要： | [目的]通过建立大鼠酒精性肝损伤病理模型,探讨甘蔗汁对大鼠酒精性肝损伤的保护作用。[方法]取大鼠40只随机分为4组,正常组、低剂量组、高剂组量和模型组。采用白酒灌胃的方法建立大鼠酒精性肝病模式,给予甘蔗汁进行保护。测定肝组织中超氧化物歧化酶（SOD）活力、丙二醛（MDA）含量,并取肝组织制作石蜡切片,HE染色,普通光镜观察。[结果]甘蔗汁能够直接提高SOD活性、降低MDA含量,且低剂量（7.5 m l/kg）和高剂量（15 m l/kg）能够有效清除活性氧和自由基,明显改善肝组织脂肪样变。[结论]甘蔗汁能抑制酒精诱导脂质过氧化反应对肝组织的损伤,对酒精性肝损伤有明显的保护作用。 |
| 关 键 词： | 甘蔗汁 酒精 肝损伤 保护作用 |
Research of the Hepatoprotective Effects of Sugar Cane Juice against Alcohol-induced Liver Injury in Rats |
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| WEI Ri-ming et al. Research of the Hepatoprotective Effects of Sugar Cane Juice against Alcohol-induced Liver Injury in Rats[J]. Journal of Anhui Agricultural Sciences, 2011, 39(6): 3606+3661-3606,3661 | |
| Authors: | WEI Ri-ming et al |
| Affiliation: | WEI Ri-ming et al(Department of Cell and Genetic,Guilin Medical University,Guilin,Guangxi 541004) |
| Abstract: | [Objective] The aim was to investigate the hepatoprotective effects of sugar cane juice through establishing alcohol-induced liver injury pathology model of rats.[Method] Forty rats were randomly divided into 4 groups,including natural group,low-dosage group,high-dosage group and model group.Duplicated the animal models of alcohol-induced liver injury by the way of gaster san hua alcohol given,then gave the sugar cane juice to carry on the protection.Superoxide dismutase(SOD) activity,malonyldiadehyde(MDA)c... |
| Keywords: | Sugar cane juice Alcohol Liver injury Hepatoprotective effects |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |