猪用生长激素脂质体对小鼠的促生长作用

目的]研究猪用生长激素（porcine somatotropin,PST）脂质体对小鼠的促生长作用与缓释效果。方法]将试验小鼠随机分组,试验组小鼠分别腹腔注射PST纯品和PST脂质体,对照组腹腔注射生理盐水。分别于7、14和28 d后称重,计算小鼠增重率。结果]试验组小鼠增重与对照组差异显著（P〈0.05）,表明PST和PST脂质体对小鼠有促生长作用,且PST脂质体具有明显的缓释效果。结论]PST脂质体缓释期长达7 d以上,具有显著的促生长效果。

Growth-Promoting Effects of Porcine Somatotropin Liposome on Mice

Objective] To research growth-promoting effects of porcine somatotropin(PST) liposome on mice and its sustained-release effects.Method] The mice were randomly divided into experimental groups and control group.The mice in the experimental groups were respectively administrated with PST and PST liposome via intraperitoneal injection,and those in the control group were administrated with saline.They were weighed on Day 7,14 and 28,and the growth rate of body weight was calculated.Result] The growth of mice had significant difference between experiment group and control group(P<0.05),which indicated that the PST and PST liposome had growth-promoting effects on mice,and the PST liposome had sustained-release effects.Conclusion] The PST liposome can promote the growth of animal and its sustained-release period can last 7 d.