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The effects of butyrate and glucagon on the proliferation of ruminal epithelial cells in culture
Authors:S. Neogrády  P. Gálfi  F. Kutas  T. Sakata
Affiliation:(1) Department of Physiology, University of Veterinary Sciences, Budapest, Hungary;(2) Physiology Group, Yakult Central Institute for Microbiological Research, Kunitachi, Japan;(3) Present address: University of Veterinary Sciences, PO Box 2, H-1400 Budapest, Hungary
Abstract:When the rate of ruminal epithelial cell proliferation was measured on the basis of 3H-thymidine incorporation into the cellular DNA, butyrate dose-dependently reduced 3H-thymidine incorporation. In contrast, glucagon at 10 and 100 pg/ml had a slight stimulatory effect on the incorporation, but only in the absence of butyrate.
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