| 乳化复合液体维生素制备工艺的初步研究 |
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| 引用本文： | 栾明娜,周玉武,徐福亮,陈大健.乳化复合液体维生素制备工艺的初步研究[J].广东畜牧兽医科技,2010,35(2):39-41. |
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| 作者姓名： | 栾明娜 周玉武 徐福亮 陈大健 |
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| 作者单位： | 1. 青岛康地恩药业有限公司,山东,青岛,266111
2. 江苏省滨海县动物卫生监督所,江苏,盐城,224500 |
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| 摘 要： | 对维生素口服溶液剂制备工艺条件进行了筛选,并对所用乳化剂种类,稳定剂用量和乳化温度进行考察。结果表明对处方量的维生素采用12.5%的乳化剂OP-10,5%的稳定剂,乳化温度60℃,所制备的液体多维在4～25℃下12个月内无沉淀析出,外观颜色无明显改变,表明本制剂所制定的工艺路线可行,适合大批量生产。
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| 关 键 词： | 液体维生素 微乳 制备工艺 |
The preparation procedure for compound vitamins solution |
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| Luan Mingna,Zhou Yuwu,Xu Fuliang,Chen Dajian.The preparation procedure for compound vitamins solution[J].Guangdong Journal of Animal and Veterinary Science,2010,35(2):39-41. |
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| Authors: | Luan Mingna Zhou Yuwu Xu Fuliang Chen Dajian |
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| Institution: | 1.Qingdao KDN Pharmaceutical Co.;Ltd;Qingdao 266111;China;2.Binhai Animal Health Supervision Institute;Yancheng 224500;China |
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| Abstract: | Factors including species of emulsifier, quantity of stabilizer and emulsifying temperature were studied to optimize the preparation procedure for compound vitamins micro-emulsion. The results showed that the optimization conditions were as follows： the concentration of emulsifier OP-10 was 12.5%, the concentration of stabilizer was 5%, and the emulsifying temperature was 60℃. There was no significant change in color and appearance, indicating that this method was suitable for mass production. |
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| Keywords: | Liquidvitamin micro-emulsion preparationprocedure |
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