氨基酸供给与内分泌互作调控乳蛋白合成的研究进展

限制性氨基酸研究是泌乳奶牛研究的热点之一,关于其影响乳蛋白合成途径而进行的一系列体内外研究表明:底物效应可能不是主要原因,更重要的是氨基酸及其构成作为信号因子对神经内分泌和细胞内信号通路的影响。本文从乳蛋白合成的影响因素入手,概括了氨基酸供给、激素分泌及二者相互作用对乳蛋白合成的调节,以期为阐明氨基酸供给影响乳蛋白合成的途径提供一定理论参考。

Recent Advances in Regulating Milk Protein Synthesis by Interaction of Amino Acid Supply and Endocrine

Limiting amino acid is one of hot topics in dairy cows studies. Previous researches, both in vitro and in vivo, show that amino acid supply and profile play a major role in milk protein synthesis by endocrine and intracellular signaling pathways rather than substrate. Focusing on the influencing factors of milk protein synthe?sis, this paper reviewed the regulation of amino acid supply, hormone secretion and their interaction on milk protein synthesis, which might provided a theoretical reference for elucidating the pathways of milk protein syn?thesis affected by amino acid supply.