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Preparation and Characterization of Chitosan Poly(acrylic acid) Magnetic Microspheres
Authors:Liang Guo  Guang Liu  Ruo-Yu Hong  Hong-Zhong Li
Institution:1. Department of radiology, The First Affiliated Hospital of Soochow University, Suzhou 215007, China; E-Mail: ;2. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, SIP, Suzhou 215123, China; E-Mail: ;3. State Key Laboratory of Multiphase Complex Systems, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080, China; E-Mail:
Abstract:Spherical microparticles, capable of responding to magnetic fields, were prepared by encapsulating dextran-coated Fe3O4 nanoparticles into chitosan poly(acrylic acid) (PAA) microspheres template. The obtained magnetic microspheres were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), and thermogravimetry (TG). The results showed that the microspheres were formed and demonstrated magnetic behavior in an applied magnetic field. In addition, magnetite particles were well encapsulated and the composite particles have high magnetite content, which was more than 40%.
Keywords:magnetic microsphere  magnetic separation  nanoparticles  chitosan poly(acrylic acid)
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