Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells |
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| Authors: | Kwang-Ho Cho Hyeung-Sik Lee Sae-Kwang Ku |
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| Institution: | 1Department of Radiological Science, College of Health Science, Catholic University of Daegu, Daegu 712-702, Korea.;2Department of Herbal Biotechnology, Daegu Haany University, Gyeongsan 712-715, Korea.;3Department of Anatomy and Histology, College of Oriental Medicine, Daegu Haany University, Gyeongsan 712-715, Korea.;4Development Team for The New Drug of Oriental Medicine (BK21 Program), Daegu Haany University, Gyeongsan 712-715, Korea. |
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| Abstract: | The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a significant decrease in most of the intestinal endocrine cells (p < 0.01) compared with the control group. The significant quantitative changes in the intestinal endocrine cell density might contribute to the development of the gastrointestinal symptoms commonly encountered in cancer patients. |
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| Keywords: | Balb/c mouse CT-26 immunohistochemistry intestinal endocrine cell tumor |
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