| 禽类性别决定与分化相关基因的研究进展 |
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| 引用本文： | 郑江霞,李显耀,杨宁.禽类性别决定与分化相关基因的研究进展[J].中国畜牧杂志,2007,43(1):47-49. |
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| 作者姓名： | 郑江霞 李显耀 杨宁 |
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| 作者单位： | 中国农业大学动物科技学院,北京,100094 |
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| 摘 要： | 禽类的性别决定机制迄今尚无定论,目前较为公认的有以下几种假说:一是W染色体上携带性别决定基因(类似于哺乳动物的SRY)决定着个体的雌性化发育;二是Z染色体上某些基因的过表达(即不受剂量补偿效应限制)引发了个体的雄性化发育;三是前2种机制共同作用。已知禽类的性别决定候选基因有W染色体上的FET1、ASW和Z染色体上的DMRT1基因。此外,常染色体上的许多基因也参与禽类的性别决定和分化过程,如SOX9,AMH,cFOXL,CYP19A1等。
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| 关 键 词： | 性别决定 性别分化 综述 Z染色体 W染色体 禽 |
| 文章编号： | 0258-7033(2007)01-0047-03 |
| 修稿时间： | 2004-11-28 |
Recent Advance in Genes of Avian Sex Determination and Differentiation |
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| ZHENG Jiang-xia,LI Xian-yao,YANG Ning.Recent Advance in Genes of Avian Sex Determination and Differentiation[J].Chinese Journal of Animal Science,2007,43(1):47-49. |
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| Authors: | ZHENG Jiang-xia LI Xian-yao YANG Ning |
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| Institution: | College of Animal Science and Technology, China Agricultural University, Beijing 100094, China |
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| Abstract: | At present, the mechanism of avian sex determination remains unknown. There are several hypotheses. The one is W sex chromosome carries a dominant ovary-determining gene. The second is Z-chromosome has a dosage mechanism (one Z for female, two Z for male). The third possibility is that both mechanisms operate. This article mainly reviewed three promising candidate genes located on the sex chromosome. The Z-linked gene, DMRT1, supports the Z-dosage model of avian sex determination. Two novel W-linked genes, ASW and FET1, represent candidate female determinants. Besides, this article also discussed some genes related to avian sex determination and differentiation, i.e. SOX9, AMH, cFOXL, CYP19A1. |
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| Keywords: | sex determination sex differentiation a review Z chromosome W chromosome avian |
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