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2.
Yoshiki YAMAYA Toshihiro WATARI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(4):421-425
Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases.
The present study tested whether dogs diagnosed with CR or CB present an atopic
predisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells among
peripheral blood CD4-positive cells (CCR4/CD4) and the serum levels of allergen-specific
IgE antibodies. We found that most dogs with CR and CB have a possibility of atopic
predisposition, and macrolide therapy constitutes an alternative to corticosteroid therapy
in controlling the clinical signs. 相似文献
3.
Kazuhiro WATANABE Kotaro HAYASHI Saku KIJIMA Chie NONAKA Kazuaki YAMAZOE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(10):1323-1325
In this study, scaling, polishing and daily tooth brushing were performed in 20 beagle
dogs, and the number of oral bacteria was determined using a bacterial counter. The dogs
were randomized into the scaling (S), scaling + polishing (SP), scaling + tooth daily
brushing (SB) and scaling + polishing + tooth daily brushing (SPB) groups. Samples were
collected from the buccal surface of the maxillary fourth premolars of the dogs
immediately after scaling and every week thereafter from weeks 1 to 8. Throughout the
study, the number of bacteria was significantly lower in the SB and SPB groups compared
with the S group. The findings suggest that daily tooth brushing inhibited oral bacterial
growth in the dogs. 相似文献
4.
Background
The etiology of canine chronic bronchitis (CB) is not completely understood, although exposure to environmental tobacco smoke (ETS) affects the airway inflammatory responses in some dogs with CB. The mechanism by which this occurs is unknown.Findings
We investigated the concentrations and methylation rates of free-floating DNA fragments in bronchoalveolar lavage fluid (BALF) from dogs with chronic bronchitis. Based on serum cotinine levels, dogs with CB were divided into 2 groups: dogs that either had or had not been exposed to ETS. Our results demonstrated that the total nucleated cell and macrophage numbers increased in BALF of ETS-exposed dogs with CB. There were no significant differences in DNA concentrations and methylation rates in BALF between the 2 groups. However, 3 out of 8 dogs exposed to ETS had high DNA methylation rates in their BALF samples.Conclusion
Our results suggest that ETS exposure leads to epigenetic modifications of cellular components in BALF in dogs diagnosed with CB. 相似文献5.
Mariko TAKAYASU Kouko HAMAMOTO Hiroshi SATOH Toshihiro ICHIJO Toru TAKAHASHI Kazuhisa FURUHAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(2):261-263
To clarify the effect of renal dysfunction on pharmacokinetics of the prokinetic agent metoclopramide (MCP), we administered intravenously 0.4 mg/kg MCP to healthy calves and calves subjected to right kidney vessel ligation (ligation) without or with a subsequent left nephrectomy (ligation plus removal). Plasma MCP concentration, glomerular filtration rate (GFR) and plasma prolactin level were measured by liquid chromatography-tandem mass spectrometry, simplified equation using iodixanol and enzyme-linked immunosorbent assay, respectively. Only in calves with ligation plus removal, plasma MCP concentrations were increased significantly 6, 8 and 12 hr after injection, showing that a negative correlation was observed between the plasma MCP concentrations and GFR value. A tendency to increase in plasma PRL concentration was noted also in these calves. In conclusions, plasma MCP concentrations depend on the GFR mode in calves, and its critical GFR value was estimated. 相似文献
6.
Toyokazu KOBAYASHI Hiroshi KOIE Arisa WATANABE Arisa INO Kazuya WATABE Mujo KIM Kiichi KANAYAMA Kazuya OTSUJI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(4):503-506
We examined the effects of chicken egg hydrolysate (also known as “bone peptide” or BP)
on bone metabolism in 5- to 8-month-old orchidectomized dogs. The bone formation marker
serum bone alkaline phosphatase (BAP) and the bone resorption marker urine
deoxypyridinoline (DPD) were used as indicators to measure changes in bone metabolism. The
following results were observed that Serum BAP was higher in dogs fed BP-enriched food
throughout the clinical investigation. Serum BAP was statistically significantly higher in
dogs fed BP-enriched food than in dogs fed non-BP-enriched food at 2 months after
orchidectomy. This suggests that BP promoted bone formation immediately after
orchidectomy. 相似文献
7.
Haney SAMIR Kazuaki SASAKI Eman AHMED Aly KAREN Kentaro NAGAOKA Mohamed EL SAYED Kazuyoshi TAYA Gen WATANABE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(5):549-556
Although color Doppler ultrasonography has been used to evaluate testicular blood flow in
many species, very little has been done in goat. Eight male Shiba goats were exposed to a
single intramuscular injection of either gonadotropin-releasing hormone (GnRH group; 1
µg/kg BW) or human chorionic gonadotropin (hCG group; 25 IU/kg BW).
Plasma testosterone (T), estradiol (E2) and inhibin (INH) were measured just before (0 hr)
and at different intervals post injection by radioimmunoassay. Testis volume (TV) and
Doppler indices, such as resistive index (RI) and pulsatility index (PI) of the
supratesticular artery, were measured by B-mode and color Doppler ultrasonography,
respectively. The results indicated an increase in testicular blood flow in both groups,
as RI and PI decreased significantly (P<0.05), but this increase was
significant higher and earlier in hCG group (1 hr) than in the GnRH group (2 hr). A high
correlation was found for RI and PI with both T (RI, r= −0.862; PI, r= −0.707) and INH in
the GnRH group (RI, r=0.661; PI, r=0.701). However, a significant
(P<0.05) correlation was found between E2 and both RI (r= −0.610) and
PI (r= −0.763) in hCG group. In addition, TV significantly increased and was highly
correlated with RI in both groups (GnRH, r= −0.718; hCG, r= −0.779). In conclusion, hCG
and GnRH may improve testicular blood flow and TV in Shiba goats. 相似文献
8.
Ammar Elakhdar Toshihiro Kumamaru Kevin P. Smith Robert S. Brueggeman Ludovic J.A. Capo-chichi Shyam Solanki 《Journal of Crop Science and Biotechnology》2017,20(3):193-204
Changes in the relative genetic performance of genotypes across environments are referred to as genotype × environment interactions (GEIs). GEIs can affect barley breeding improvement for salt tolerance because it often complicates the evaluation and selection of superior genotypes. The present study evaluated the GEIs over 60 barley genotypes for yield components and grain yield in six salinity environments in North Delta, Egypt. Data were analyzed using the additive main effects and multiplicative interaction (AMMI) and Tai’s stability parameters. GEIs effects on yield explained 20.3, 20.1, 14.6, and 33.0% of the total variation besides, the first two principal components account for 67.3, 56.3, 64.3, and 83.7% of the explained variance in the four sets, respectively. Six genotypes namely G-4, G-7, G-20, G-34, G-36, and G-39 were found to be most stable and high yielding across environments (GY >2.00 t ha-1), and located close to zero projection onto the AEC ordinate. Tai’s stability parameters demonstrated that these genotypes were more responsive to the environmental changes. The genotypes G-50 and G-53 showed perfect/static stability (α = -0.95, -0.91, respectively). In contrast, the genotype; G-36 had α = 0 and λ = 1.10, indicating parallel with the environmental effects followed by G-44. Overall, we found that GEIs for grain yield are highly significant in all sets, suggesting that responded differently across environments. This interaction may be a result of changes in genotypes’ relative performance across environments, due to their differential responses to various abiotic factors. 相似文献
9.
Issei Nishiki Mikiko Furukawa Sho Matui Toshiaki Itami Toshihiro Nakai Terutoyo Yoshida 《Fisheries Science》2011,77(3):367-373
In Japan, Lactococcus garvieae infection has been the main fish disease in aquaculture. Although commercial oral and injectable vaccines have been used
to prevent L. garvieae infection in Japan, L. garvieae has been isolated not only from unvaccinated fish but also from vaccinated fish in which immunity induced by vaccination
had diminished. In order to obtain epidemiological information on this fish pathogen, we conducted biased sinusoidal field
gel electrophoresis (BSFGE) pattern analysis and phage typing of L. garvieae isolates (n = 427) from fish in Japan. These isolates were obtained from 13 different fish species between 1980 and 2007. In the BSFGE
analysis, L. garvieae isolates were classified into 17 groups (S1–S17) based on the SmaI digestion patterns and into four groups (A1–A4) based on the ApaI digestion patterns. Phage typing revealed five different phage susceptibility profiles (A–E) in L. garvieae isolates. Since 2005, comparisons of the results of phage typing and BSFGE have indicated the presence of a novel genotype
(S16/A4) with phage type E. All the strains belonging to this type showed lincomycin sensitivity. 相似文献
10.
Toshihiro Hata Kenji Umemura Hidefumi Yamauchi Akihiro Nakayama Shuichi Kawai Hikaru Sasaki 《Journal of Wood Science》2001,47(2):115-123
A new spiral-winder was developed for continuous manufacturing of cylindrical laminated veneer lumber (LVL), and a suitable resin adhesive for this cylindrical LVL manufacturing system was investigated. This phase was followed by trial manufacturing and evaluation of cylindrical LVL with the optimum resin adhesive identified. The results are summarized as follows. (1) The shortest gelation time was recorded with a mixture of two commercial resorcinol based resins (DF-1000 and D-33) at a weight ratio of 2575. (2) Bath temperature had a remarkable effect on the gelation time of the adhesive mix. (3) High bonding strength was recorded by 2575 DF-1000/D-33 adhesive mix at a high press temperature despite a short pressing duration. Based on the results of items (1) to (3), 2575 DF-1000/ D-33 is recommended for use in the new spiral-winder. (4) The mechanical properties of cylindrical LVL could be improved by using 2575 DF-1000/D-33 with wider veneer width and longer pressing time. (5) The mechanical properties, especially the modulus of rupture, of the cylindrical LVL manufactured require further improvement for practical structural application. 相似文献