Curcumin,a Compound from Natural Sources,a True Scientific Challenge – A Review

Curcumin, a plant-derived polyphenolic compound, naturally present in turmeric (Curcuma longa), has been the subject of intensive investigations on account of its various activities. The implementation of safe, beneficial and highly functional compounds from natural sources in human nutrition/prevention/therapy requires some modifications in order to achieve their multi-functionality, improve their bioavailability and delivery strategies, with the main aim to enhance their effectiveness. The low aqueous solubility of curcumin, its rapid metabolism and elimination from the body, and consequently, poor bioavailability, constitute major obstacles to its application. The main objectives of this review are related to reported strategies to overcome these limitations and, thereby, improve the solubility, stability and bioavailability of curcumin. The effectiveness of curcumin could be greatly improved by using nanoparticle-based carriers. The significance of the quality of a substance delivery system is reflected in the fact that carrying curcumin as a food additive/nutrition also means carrying the active biological product/drug. This review summarizes the state of the art, and highlights some examples and the most significant advances in the field of curcumin research.     

Gill Reaction to Pollutants from the Tamiš River in Three Freshwater Fish Species,Esox lucius L. 1758, Sander lucioperca (L. 1758) and Silurus glanis L. 1758: A Comparative Study

The study evaluated the effects of waterborne pollutants from the Tami? River on gill histology and possible differences in gill reaction patterns between three freshwater fish species, pike Esox lucius L. 1758, pike‐perch Sander lucioperca (L. 1758) and wels catfish Silurus glanis L. 1758 from the Tami? River. Gills from analysed fish species showed moderate to intense histopathological alterations. The most frequent progressive alteration was hyperplasia of epithelium, whereas the most frequent regressive alteration was epithelial lifting. Circulatory disturbances were most often manifested in the form of hyperaemia. During comparative analysis, differences in gill indices, reaction and alteration indices, as well as in gill and filament prevalence between analysed species, were observed. Although all analysed fish species did show both progressive and regressive alterations, there was a significant difference in the level of expression of these reaction patterns. Gill index obtained for pike clearly stands out as the lowest. Wels catfish showed the highest progressive reaction index, significantly higher in comparison with the other two species (P < 0.05), while pike‐perch showed the highest regressive reaction index, also significantly higher in comparison with the other species (P < 0.001). These results may implicate species‐specific gill reactions and thus present a useful tool for better understanding toxic mechanisms of various pollutants.     

Analysis of genetic diversity among Macrophomina phaseolina (Tassi) Goid. isolates from Euro-Asian countries

Journal of Plant Diseases and Protection - The study assessed the genetic variability among Macrophomina phaseolina (Tassi) Goid. isolates originating from six different countries (Turkey,...     

Maize defence mechanisms against the European corn borer,Ostrinia nubilalis Hübner (Lepidoptera: Crambidae)

Maize is arguably the most widely grown crop in the world, but it is often associated with one of its major insect pests, the European corn borer (ECB). The damage caused by this species to maize production is generally variable, but in many cases it is economically significant. This review paper provides an overview of the research findings on the natural plant defence mechanisms against ECB larvae published till now. What is resistance and how it is achieved, what is the chemical response of maize plants to insect feeding and how tolerance can be increased. A short introduction in breeding for resistance and a discussion if the mentioned traits can be used in conventional breeding in order to create maize hybrids less affected by ECB are given.     

Bemerkungen über die Populationsbewegungen der Mittelmeerfruchtfliege (Ceratitis capitata Vied.) an der jugoslawischen Adriaküste

Zusammenfassung Untersuchungen über den Massenwechsel und die Biologie der MittelmeerfruchtfliegeCeratitis capitata Vied. während der letzen 5 Jahre führten zu folgenden Ergebnissen:1. Die Mittelmeerfruchtfliege, die bis 1947 in ganz Jugoslawien unbekannt war, kommt seit mindestens zehn Jahren auch an der Adriaküste vor.2. Erst im Jahre 1958 erwies sich die Fruchtfliege als Schädling verschiedener Obstarten.3. Wie aus Beobachtungen in Obstanlagen an der Adriaküste hervorgeht, befällt die Fliege in erster Linie Pfirsich, ferner auch Birne, Kaki, Feige, Apfel, Pflaume, Orange und grünen Paprika. Im Laboratorium gelang die Zucht außerdem noch an Banane, nicht aber an Tomate und Trauben.4. ObwohlC. capitata ein polyphages Insekt ist, befällt sie an einigen Stellen, wo sie regelmäßig große Häufigkeit aufweist, nur Pfirsich (Split, Debeli Rti) bzw. nur Kaki (Ankaran). In manchen Obstgärten lebt sie aber an verschiedenen Früchten (Podstrana, Stroanac). Es gibt bei der Fruchtfliege also auf Obstarten spezialisierte Populationen und solche, die an verschiedenen Obstarten vorkommen.5. Unter den in unserem Küstenland herrschenden Klimabedingungen kann die Fruchtfliege in einem Jahr 4–5 Generationen entwickeln. Die Herbstgeneration verpuppt sich Ende Oktober/Anfang November in der Erde, die Imagines verlassen bis Januar die Puppen und warten auf das Reifen der ersten, frühen Pfirsichsorten. Die gleiche Überwinterungsweise wurde auch an der Olivenfliege beobachtet.6. Mit Angelica-Öl versehene Fanggläser brachten nur zum Teil befriedigende Ergebnisse, da dieser Lockstoff nur die Männchen anzieht, aber auch nur in der Zeit, in der die Fliegen überhaupt selten sind. Im Spätsommer und Herbst wirkt ein aus Kleie und Biammonphosphat bereiteter Köder auf beide Geschlechter stark anlockend.     

Free radical scavenging activity of three Equisetum species from Fruska gora mountain

The scavenger activities of Equisetum arvense, Equisetum ramosissimum and Equisetum telmateia aboveground parts phosphate buffer (pH 7) extracts were evaluated using three different methods: DPPH assay, ESR and NO radical inhibition assay. Total reducing power was determined by FRAP assay. The E. telmateia extract demonstrated the most relevant scavenger and antioxidant properties. ESR signal of DMPO-OH radical adducts in the presence of E. telmateia phosphate buffer (pH 7) extract was reduced to 98.9% which indicated that E. telmateia could be a useful source of antioxidants with huge scavenger ability.     

Parasitoid complex (Hymenoptera, Braconidae, Aphidiinae) of Aphis craccivora Koch (Hemiptera: Aphidoidea) in Iran

The parasitoids (Hymenoptera, Braconidae, Aphidiinae) of the cowpea aphid, Aphis craccivora Koch, were investigated throughout two far distant provinces, Tehran and Sistan-Baluchestan. Colonies of the cowpea aphid were collected from different host plants and reared under laboratory conditions until the parasitoids emerged. The aphids were parasitized by an expected range of parasitoids. The species were Aphidius colemani Viereck, Lysiphlebus fabarum (Marshall), Lysiphlebus confusus Tremblay and Eady, Lysiphlebus testaceipes (Cresson), Binodoxys acalephae (Marshall), Binodoxys angelicae (Haliday), Praon volucre (Haliday) and Ephedrus persicae Froggatt. L. testaceipes is reported here for the first time in Iran. The most common species was L. fabarum followed by B. acalephae and L. confusus. A key is provided for identification and host plant associations are considered.     

Novel fibrinolytic enzyme in fermented shrimp paste, a traditional asian fermented seasoning

A novel fibrinolytic enzyme was purified from fermented shrimp paste, a popular seasoning used in Asian countries. The enzyme is a monomer with an apparent molecular weight of 18 kDa, and it is composed primarily of beta-sheet and random coils. The N-terminal amino acid sequence was determined to be DPYEEPGPCENLQVA. It is a neutral protease with an optimal activity from pH 3 to 7. No inhibition was observed with PMSF, Pepstatin A, E64, and 1,10-phenanthroline, but the enzyme was slightly inhibited by EDTA and Cu(2+). It was relatively specific to fibrin or fibrinogen as a protein substrate, yet it hydrolyzed none of the plasma proteins in the studies. In vitro, the enzyme was resistant to pepsin and trypsin digestion. It also had an anticoagulant activity measured with activated partial thrombin time and prothrombin time tests. The novel fibrinolytic enzyme derived from traditional Asian foods is useful for thrombolytic therapy. In addition, this enzyme has a significant potential for food fortification and nutraceutical applications, such that its use could effectively prevent cardiovascular diseases.