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TOSHIE ISERI KAZUTAKA YAMADA KOUSAKU CHIJIWA RYOHEI NISHIMURA SATORU MATSUNAGA REINA FUJIWARA NOBUO SASAKI 《Veterinary radiology & ultrasound》2007,48(4):328-331
To establish optimal imaging conditions for enhanced computed tomography (CT) for canine pancreatic tumors, 10 healthy beagles were subjected to dynamic CT. This technique was then applied to a dog with suspected insulinoma. The changes in mean peak enhancement and the delay time of the aorta and pancreas were determined. In normal beagles, maximal arterial and pancreatic CT enhancement was observed at 15 +/- 2 s (795 +/- 52 Housfield unit [HU]) and 28 +/- 9 s (118 +/- 16HU) after contrast medium injection, respectively. Multiphase enhanced CT was performed in a pug with suspected insulinoma using the CT protocol defined for the normal beagles with some parameters modified; the images were acquired at the arterial (14 s after contrast medium injection), pancreatic (after 28 s), and equilibrium (after 90 s) phases; scanning was followed by exploratory laparotomy. CT images were characterized by an enhanced mass in the left pancreatic lobe at the arterial phase, during which the difference between the CT values of the mass and normal pancreas was the highest. Histopathologic diagnosis of the pancreatic mass was insulinoma. Thus, it appears that enhanced CT imaging can be used to delineate the pancreas from a pancreatic mass, and it may be helpful in deciding the need for surgery. 相似文献
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Munekazu NAKAICHI Toshie ISERI Hiro HORIKIRIZONO Yusuke SAKAI Harumichi ITOH Hiroshi SUNAHARA Kazuhito ITAMOTO Kenji TANI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2020,82(11):1671
An 11-year-old male toy poodle with neurological symptoms was diagnosed with a macroscopic pituitary tumor, which produced adrenocorticotropic hormone. Radiation therapy with a linear accelerator was performed for the pituitary tumor, and resulted in good local tumor control. However, serum endogenous adrenocorticotropic hormone concentrations were uncontrollable even after the tumor disappeared. Abdominal computed tomography revealed splenic masses, and splenectomy was performed. Histopathological examination of the surgical specimen showed tumor cells with eosinophilic and finely granular cytoplasm suggestive of endocrine origin. Since these cells were positive for adrenocorticotropic hormone, the case was diagnosed as a pituitary carcinoma with distant metastasis. Necropsy revealed multiple metastases to the abdominal organs. This is the first case report describing canine pituitary carcinoma with distant metastasis. 相似文献
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Toshie ISERI Junichiro SHIMIZU Hideo AKIYOSHI Kayo KUSUDA Akiyoshi HAYASHI Keiichiro MIE Takeshi IZAWA Mitsuru KUWAMURA Jyoji YAMATE Yuka FUJIMOTO Fumihito OHASHI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(7):857-860
A Bengal tiger was presented for evaluation of weakness, ataxia and inappetance. Computed
tomography (CT) and magnetic resonance imaging (MRI) revealed a mass extending from the
T7-8 vertebral body to the left rib and compressing the spinal cord. On CT, the bone
destruction and sequestrum were shown. On MRI, the multilobulated mass appeared hypo- to
isointense in T1-weighted and hyperintense in T2-weighted images. The tiger died after
imaging, most likely from renal failure. Chordoma without metastasis was diagnosed on
necropsy. The imaging characteristics were similar to those found in chordoma in humans.
This report describes the use of CT and MRI in an exotic species. 相似文献
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Mizuki KURAMOCHI Takeshi IZAWA Mayuka HORI Kayo KUSUDA Junichiro SHIMIZU Toshie ISERI Hideo AKIYOSHI Fumihito OHASHI Mitsuru KUWAMURA Jyoji YAMATE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(7):893-895
A 19-year-old female Bengal tiger (Panthera tigris tigris) was presented
with hind limb weakness, ataxia and respiratory distress. Computed tomography revealed a
mass between the left side of the T7 vertebra and the base of the left 7th rib. The tiger
then died, and necropsy was performed. Grossly, the vertebral mass was 6 × 5.7 × 3 cm, and
invaded the adjacent vertebral bone and compressed the T7 spinal cord. Histologically, the
mass was composed of large, clear, vacuolated and polygonal cells with osteochondral
matrix. Cellular and nuclear atypia were moderate. The vacuolated cells stained positively
for cytokeratin and vimentin and negatively for S-100. Based on these findings, the
present case was diagnosed as a vertebral chordoma; the first report in a tiger. 相似文献
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Toshie ISERI Masaya NAKAMORI Yuka FUJIMOTO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(12):1877
General anesthesia reduces hepatic blood flow (HBF) from circulatory depression. Total intravenous anesthesia (TIVA) is associated with decreased circulatory depression compared to inhalation anesthesia, and epidural anesthesia using local anesthetics increases blood flow by blocking the sympathetic nerves and expanding blood vessels. We investigated the effects of thoracolumbar epidural anesthesia with TIVA on HBF in dogs. Six Beagle dogs had epidural catheters placed between T13 and L1 and were anesthetized with propofol and vecuronium. Physiological saline (control) or 2% lidocaine (0.2 ml/kg, followed by 0.2 ml/kg/hr) was administered at 1–2 weeks intervals. Heart rate (HR), cardiac index (CI), mean arterial pressure (MAP), and systemic vascular resistance index (SVRI) were recorded at 10-min intervals from before epidural injections (T0) to 110 min. Indocyanine green test was used to measure HBF during the awake state and until 90 min after epidural injections. HR and CI did not differ between treatments. MAP and SVRI after lidocaine were significantly lower than those of controls, and the lowest MAP value was 65 ± 11 mmHg at T10. Compared to T0, after lidocaine treatment, HBF was significantly higher at T30, T60 and T90 (P<0.05); while, after control treatment, no significant change was evident at any time point. Despite a decrease in MAP by this technique, HBF was either maintained at pre-anesthetic levels or increased in comparison to controls, probably due to vasodilation of the hepatic artery induced by the selective blockade sympathetic ganglia. 相似文献
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Munekazu NAKAICHI Toshie ISERI Hiro HORIKIRIZONO Misa KOMINE Harumichi ITOH Hiroshi SUNAHARA Yuki NEMOTO Kazuhito ITAMOTO Kenji TANI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(6):911
A male 25-month-old Dalmatian dog attended our veterinary hospital because of anorexia and high circulating liver enzyme activities. Abdominal computed tomography showed a slightly small liver with rounded edges, and laparoscopic examination showed that the liver was yellowish. Histopathological examination revealed multifocal necrosis of hepatocytes and severe chronic hepatitis. Rhodanine staining showed severe copper accumulation in hepatocytes and a quantitative analysis of the copper content of the liver showed substantial accumulation (10.3 mg/g dry mass), suggesting a diagnosis of copper-associated hepatitis. Previously reported canine mutation in the COMMD1, the gene responsible for the copper-associated hepatitis in the Bedlington terrier, was not identified. To our knowledge, this is the first report of copper-associated hepatitis in a Dalmatian in Japan. 相似文献
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