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Philip R. Woods DVM PhD Wm. Tod Drost DVM Cyril R. Clarke BVSc PhD Carolyn J. Rodebush RT 《Veterinary radiology & ultrasound》2000,41(1):85-88
Ten healthy horses were injected intravenously with 99mTc-MAG3 and the disappearance of radioactivity from the blood was measured. The total body clearance (Cl(B)) and elimination half-life (t1/2(beta)) were 7.9 +/- 1.5 ml/kg/minute and 32.8 +/- 4.1 minutes, respectively. The disappearance of 99mTc-MAG3 from the blood of 2 horses with compromised renal function was also measured. The data suggest that 99mTc-MAG3 is a useful and clinically applicable radiopharmaceutical for measurement of effective renal blood flow in the horse. 相似文献
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THE EFFECTS OF A UNILATERAL ULTRASOUND-GUIDED RENAL BIOPSY ON RENAL FUNCTION IN HEALTHY SEDATED CATS
Wm Tod Drost DVM George A. Henry DVM James H. Meinkoth DVM MS PnD J. Paul Woods DVM MS Mark E. Payton PhD Carolyn Rodebush ASRT 《Veterinary radiology & ultrasound》2000,41(1):57-62
Complications of renal biopsies are well documented except for the change in renal function after a biopsy. Eighteen healthy, adult cats were divided into two groups (n = 9 cats/group). For the measurement of global and split renal function, Group 1 used the renal uptake of 99mTc-DTPA and Group 2 used the renal uptake of 99mTc-MAG3. Scintigraphic data were collected on days (-4), (-3), 0, 1, 2, and 4 post renal biopsy. Using ultrasound guidance, biopsies were taken from the right renal cortex on dO, before acquiring scintigraphic images. P - values less than 0.10 were considered significant due to the limited number of observations. The only statistically significant change (p = 0.08) in global renal function detected was by day following a unilateral renal biopsy. Cats imaged using 99mTc-MAG3 had discernible liver activity. A unilateral, ultrasound guided renal biopsy has minimal effect on renal function in normal, healthy sedated cats. 相似文献
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Rodebush WH 《Science (New York, N.Y.)》1923,57(1473):358-359
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Rodebush WH 《Science (New York, N.Y.)》1924,59(1533):430-433
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