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Toyoshima K Noguchi R Hosokawa M Fukunaga K Nishiyama T Takahashi R Miyashita K 《Journal of agricultural and food chemistry》2004,52(8):2372-2375
Sardine oil was obtained by centrifugation of surimi wastewater without heating or chemical refining. This oil (CE) showed light yellow color and the peroxide value was less than 1.0 meq/kg. The main lipid class of CE was triacylglycerol (TG) (>99%). These features indicate that CE can be directly used as food materials without further purification. Commercial sardine oil (CO) is usually prepared via some kind of refining process with high temperature (250 degrees C) and chemical treatment. The comparative study on the physiological effects of these sardine oils (CE and CO) revealed that the dietary sardine oils were more effective in reducing abdominal fat pads, plasma total cholesterol, and TG levels of rats than was a soybean oil diet (control). Furthermore, these effects were greater in CE than CO, although there was little difference in the fatty acid composition of both oils. Although the main lipid class of CE was TG (>99%), CE was prepared by centrifugation from surimi waste and directly used as dietary fat without further purification. Therefore, CE may contain some kinds of minor components, which could be attributed to the higher physiological activity of CE. To reveal the involvement of the minor compounds in CE, we prepared TG from CE by column chromatography and measured its effect on lipid metabolism of rats. TG from CE also showed the reducing effects on abdominal fad pads and plasma lipid levels. The effect of TG from CE was almost the same as that of original CE, suggesting that the higher nutritional activity of CE than CO may not be due to the minor compounds in CE. 相似文献
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Izumi Noguchi Takunori Katoh Shigekatsu Sakai Riki Iwata Masayuki Akiyama Hideyuki Ohtsuka Kouichi Sakata Hirohide Aga Yutaka Matsumoto 《Water, air, and soil pollution》2001,130(1-4):421-426
Snowcover surveys were carried out in Hokkaido, northern Japan. Snowpack samples were collected using a steel pipe at 80 sites in 1988, 69 sites in 1992, and 66 sites in 1996 and 2000 during the time when the water equivalents of the snowcover are the greatest. Spatial distribution maps of water equivalents and of the concentrations and the accumulated amounts of hydrogen, non-sea-salt sulfate and non-sea-salt calcium ion of the snowcover drawn by Kriging method are discussed. The distribution maps show that water equivalents and the accumulated amounts of hydrogen and non-sea-salt sulfate in all the sample years were largest in the Japan Sea region, as were the ion concentrations of hydrogen and non-sea-salt sulfate. It was estimated this was caused by air pollutants transported from a great distance. The ratio of areas below pH 5.0 increased temporally from 1988 (20%) to 1992, 1996 and 2000 (66–80%). This trend was estimated to be affected by a decline of non-sea-salt calcium concentrations derived from alkaline road dust. In addition, the effect of snowcover components was assessed by comparison between the acid loads of the snowcover and the acid neutralizing capacity of lake water. We found that lakes in the middle of the Japan Sea coast have the potential to be acidified by snowmelt. 相似文献
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A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A 总被引:2,自引:0,他引:2
Kawaguchi R Yu J Honda J Hu J Whitelegge J Ping P Wiita P Bok D Sun H 《Science (New York, N.Y.)》2007,315(5813):820-825
Vitamin A has diverse biological functions. It is transported in the blood as a complex with retinol binding protein (RBP), but the molecular mechanism by which vitamin A is absorbed by cells from the vitamin A-RBP complex is not clearly understood. We identified in bovine retinal pigment epithelium cells STRA6, a multitransmembrane domain protein, as a specific membrane receptor for RBP. STRA6 binds to RBP with high affinity and has robust vitamin A uptake activity from the vitamin A-RBP complex. It is widely expressed in embryonic development and in adult organ systems. The RBP receptor represents a major physiological mediator of cellular vitamin A uptake. 相似文献
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S. Izhar M. Bar-Joseph A. Rosner A. Navon R. Salomon E. Swirski D. Blumberg M. Wysoki Y. Izhar D. Gerling A. R. Horowitz J. Baumgaertner M. J. Berlinger R. Dahan Sara Mordechi Riki Oren R. Or Venezia Melamed-Madjar U. Gerson K. R. S. Ascher Miriam Eliyahu I. Ishaaya Z. Mendelson J. E. Casida S. Cohen A. S. Perry H. Bar Yechezkel G. Alon O. Elsner G. Stern 《Phytoparasitica》1985,13(1):69-79
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