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1.
Abrams MD 《Tree physiology》1988,4(3):263-273
Water relations of co-occurring understory saplings of Quercus ellipsoidalis E.J. Hill, an early successional, xeric species, Populus tremuloides Michx., an early successional, mesic species, and Acer rubrum L., a late successional species that occurs on both wet and dry sites, were evaluated on four dates during the 1986 growing season. The understory was characterized by high soil water content, low irradiance and low vapor pressure deficit throughout the growing season. Stomatal conductance and calculated transpiration flux were lowest for A. rubrum and highest for P. tremuloides and Q. ellipsoidalis. Except early in the growing season, leaf water potentials were lower in P. tremuloides than in the other species. Populus tremuloides had the highest bulk modulus of elasticity, Q. ellipsoidalis the lowest. Over the growing season, Populus tremuloides and Q. ellipsoidalis, but not A. rubrum, exhibited a decrease in osmotic potential at both full and zero turgor. Of the three species, Populus tremuloides exhibited the sharpest decrease in leaf water potential and turgor pressure with decreasing relative water content. 相似文献
2.
Josephine A. Dornbusch Laura E. Selmic Pin‐Chieh Huang Jonathan P. Samuelson Eric M. McLaughlin Vincent A. Wavreille Jessica A. Ogden Brittany Abrams Alex Kalamaras Eric Green Eric T. Hostnik Lincoln Every Jason A. Fuerst Ryan Jennings Christopher Premanandan Joshua N. Lorbach Sarah C. Linn Aneesh Alex Janet E. Sorrells Lingxiao Yang Stephen A. Boppart 《Veterinary surgery : VS》2021,50(1):111-120
3.
Sorenmo K Samluk M Clifford C Baez J Barrett JS Poppenga R Overley B Skorupski K Oberthaler K Van Winkle T Seiler G Shofer F 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(6):1347-1354
BACKGROUND: Canine splenic hemangiosarcoma (HSA) is a fatal malignancy, and most affected dogs die within a few months of diagnosis. Most dogs present with signs from tumor rupture, resulting in hemoabdomen and intra-abdominal dissemination. The abdomen is also the main site of disease recurrence. HYPOTHESIS: Intraperitoneal (IP) administration of doxorubicin will delay or prevent intra-abdominal tumor recurrence and prolong survival in dogs with HSA. ANIMALS: Fourteen dogs with splenic HSA. METHODS: A prospective, unmasked, uncontrolled clinical trial. After staging of disease status and splenectomy, pegylated liposomal encapsulated doxorubicin was administered intraperitoneally (1 mg/kg body weight) every 3 weeks for 4 cycles. All dogs were monitored for recurrence of HSA. Samples of plasma and abdominal fluid were collected for measurement of doxorubicin concentration and pharmacokinetic analysis. Nonlinear mixed-effect modeling was used to describe the pharmacokinetics of liposomal doxorubicin administered IP. RESULTS: All 14 dogs died, 12 because of HSA and 2 from other causes. Postmortem examination was performed on 12 dogs. All 12 dogs died because of HSA-related causes and had hepatic metastases and hemoabdomen. The IP-treated dogs had fewer serosal, mesenteric, and omental metastases than historical controls treated with systemic doxorubicin. Results of the postmortem examination and pharmacokinetic analysis confirmed that IP delivery of doxorubicin resulted in an effective drug concentration with a clearance comparable with that after i.v. delivery. CONCLUSIONS AND CLINICAL IMPORTANCE: IP pegylated liposomal encapsulated doxorubicin administration did not prevent intraabdominal recurrence of HSA in dogs. 相似文献
4.
Kate L. Constantine Fernadis Makale Idah Mugambi Duncan Chacha Harrison Rware Alexander Muvea Vincent K. Kipngetich Justice Tambo Adewale Ogunmodede Djami Djeddour Corin F. Pratt Ivan Rwomushana Frances Williams 《Pest management science》2023,79(11):4343-4356
Background
In Kenya, rice (Oryza sativa L.) is mainly produced under irrigation by small-scale farmers. Mwea irrigation scheme (MIS) in Kirinyaga County accounts for 80–88% of rice production. Here, rice is the main source of livelihood and a source of revenue generation for the county. However, a recently established invasive freshwater snail, Pomacea canaliculata (Lamarck) (family: Ampullariidae), a species of apple snail, presents a serious threat to rice production.Results
Household surveys, focus group discussions and key informant interviews highlight apple snail as a serious problem in MIS. Households that observed at least a moderate level of infestation (>20% of cultivated area) experienced significant reductions in rice yield (~14%) and net rice income (~60%). Farmers reported increased use of chemical pesticides for management of apple snail. In addition, the cost of hired labor for physical removal of egg masses and snails is resulting in substantial negative effects on net income. Farmer age, area of land owned, responsibility for decision-making, receipt of extension advice, training, and membership of a farmer organization, were all statistically significant variables to explain farmers awareness of the need for area-wide apple snail management.Conclusion
Strategies to limit the spread of apple snail are urgently needed. A Multi-Institutional Technical Team (MITT) has been established to spearhead management efforts and consolidate advice to farmers on how to manage apple snail. However, without action to mitigate spread, the consequences could be disastrous for rice production and food security in Kenya, and for other rice growing regions across Africa. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. 相似文献5.
Hunter J. Piegols Brittany E. Abrams Janis M. Lapsley Megan T. Cray Josephine A. Dornbusch Christina Murphy Brandan G. Wustefeld-Janssens Carlos H. Souza Marine Traverson Pierre Amsellem Elroy Williams Owen T. Skinner Julius M. Liptak Julie A. Stephens Laura E. Selmic 《Veterinary and comparative oncology》2023,21(4):673-684
Adrenalectomies for canine adrenal tumours are associated with peri-operative morbidity and mortality. Objectives of this study included assessing the prognostic value of tumour- or surgery-related variables in predicting peri-operative mortality and overall survival in dogs undergoing adrenalectomies for primary adrenal tumours as well as pre-treatment with phenoxybenzamine on survival to discharge with pheochromocytomas specifically. A multi-institutional retrospective cohort study was performed across nine institutions. Electronic medical record searches identified 302 dogs which met the inclusion criteria. Data collected included dog-related, tumour-related, treatment-related, surgery-related, and outcome variables. Univariate and multivariable logistic regression and cox proportional hazards models were used to identify variables associated with death prior to discharge and tumour-related survival. Overall, 87% of dogs survived to discharge with a tumour-related survival time of 3.96 years. Post-operative complications were reported in 25%. Increased surgical time (p = 0.002) and pre-surgical medical treatment other than phenoxybenzamine (p = 0.024) were significantly associated with increased peri-operative mortality while ureteronephrectomy (p = 0.021), post-operative pancreatitis (p = 0.025), and post-operative aspiration pneumonia (p < 0.001) were significantly associated with decreased overall survival. Phenoxybenzamine pretreatment had no effect on peri-operative mortality. Thirty-seven of 45 (82%) dogs with pheochromocytomas not pretreated survived to discharge, and 50 of 59 (85%) dogs with pheochromocytomas pretreated with phenoxybenzamine survived to discharge (p = 0.730). This study provides information on risk factors for death prior to discharge and tumour-related survival that may help guide clinical management and owner expectations. In addition, the study findings challenge the previously reported benefit of phenoxybenzamine for pretreatment of dogs undergoing adrenalectomies for pheochromocytomas. 相似文献
6.
7.
Natural products derived from micro-organisms, plants and animals possess inherent biological properties and are, therefore, an excellent source of lead chemicals on which to base synthesis programmes employing rational design techniques. Only a fraction of the fungal kingdom has been screened systematically for novel metabolites despite their suspected potential. Moreover, the fungi are generally manipulable in laboratory culture systems and, because of their developmental versatility, they offer tremendous potential as sources of novel metabolites. Primary assay systems based on biochemical targets provide an effective means of screening microbial products; such assay systems also efficiently support chemical purification of lead activities and rapid elucidation of new chemical templates. 相似文献
8.
Barone G Ziemer LS Shofer FS Steinberg SA 《Journal of the American Veterinary Medical Association》2002,220(10):1499-1502
OBJECTIVE: To determine prevalence of seizures after use of iohexol for myelography and identify associated risk factors in dogs. DESIGN: Retrospective study. ANIMALS: 182 dogs that received iohexol for myelography in 1998. PROCEDURE: Medical records were reviewed for age, breed, sex, weight, dose and total volume of iohexol, injection site, number of injections, lesion type and location, total duration of anesthesia, duration from time of iohexol injection to recovery, presence and number of seizures, and whether surgery followed the myelogram. RESULTS: 39 (21.4%) dogs had at least 1 generalized seizure during or after myelography. Injection site was strongly associated with prevalence of seizures, and risk of seizure was significantly higher after cerebellomedullary injections, compared with lumbar injections. Mean total volume of iohexol administered to dogs that had seizures was significantly higher, compared with that administered to dogs that did not have seizures, although dosage did not differ between groups. Weight was significantly correlated with risk of seizure, and dogs that weighed > 20 kg (44 lb) had higher prevalence of seizures than dogs that weighed < 20 kg. CONCLUSIONS AND CLINICAL RELEVANCE: It is preferential to administer iohexol via the L5-6 intervertebral space to minimize the risk of seizures. Higher prevalence of seizures in large dogs, compared with smaller dogs, may be caused by administration of larger total volumes of contrast agent per volume of CSF. 相似文献
9.
Dobbins S Brown NO Shofer FS 《Journal of the American Animal Hospital Association》2002,38(6):507-514
In this prospective, randomized, blinded study, 68 clinically healthy cats that had onychectomy (n = 20), onychectomy and castration (n = 20), or onychectomy and ovariohysterectomy (n = 28) were randomly assigned to one of four postoperative analgesic treatment groups: buprenorphine (0.01 mg/kg body weight, intramuscularly [IM]), oxymorphone hydrochloride (0.05 mg/kg body weight, IM), ketoprofen (2 mg/kg body weight, IM), and placebo (physiological saline). Sedation scores, visual analog pain scores, cumulative pain scores, serum cortisol concentration, and appetite were used to assess postoperative analgesic effect. Buprenorphine demonstrated the highest efficacy with the lowest cumulative pain scores and serum cortisol levels. 相似文献
10.
Deahl KL Cooke LR Black LL Wang TC Perez FM Moravec BC Quinn M Jones RW 《Pest management science》2002,58(9):951-958
In recent years, late blight, caused by Phytophthora infestans (Mont) De Bary, has increased in severity in many parts of the world, and this has been associated with migrations which have introduced new, arguably more aggressive, populations of the pathogen. In Taiwan, late blight has been endemic on outdoor tomato crops grown in the highlands since the early 1900s, but recent epidemics have been more damaging. To ascertain the present status of the Taiwanese population of P infestans, 139 isolates of the pathogen collected and maintained by the Asian Vegetable Research and Development Center (AVRDC) were characterized using mating type, metalaxyl sensitivity, allozyme genotype, mitochondrial haplotype and RFLP fingerprinting. Up to 1997, all isolates were found to belong to the old clonal lineage of P infestans (US-1 and variants), but in isolates from 1998 a new genotype appeared, and by 2000 this had apparently completely displaced the old population. This new genotype was an A1 mating type and has the dilocus allozyme genotype 100/100/111, 100/100 for the loci coding for glucose-6-phosphate isomerase and peptidase, respectively. These characters, together with RG57 fingerprinting, indicated that these isolates belonged to the US-11 clonal lineage, a minority (11%) being a previously unreported variant of US-11. Whereas metalaxyl-resistant isolates were not detected in the old population, 96% of the new genotypes proved resistant, with the remainder being intermediate in sensitivity. It may be inferred from this sudden, marked change in the characteristics of the Taiwanese P infestans that a new population of the pathogen was introduced around 1997-98 and that this may well have already been metalaxyl-resistant when it arrived, although a role for in situ selection cannot be excluded. 相似文献