Small mammal virology.

Most viral infections in small mammals are transient and rarely produce clinical signs. When clinical signs do appear, they are often of a multifactorial etiology such as respiratory infection with Sendai virus and the bacteria M. pulmonis in rodents. Diagnosis is generally made based on clinical signs, while therapy involves treatment for concurrent bacterial infections and supportive care. Small mammals may carry zoonotic viruses such as LCMV, but natural infections are uncommon. Viral diseases are rare (or largely unknown) for hedgehogs, chinchillas, and prairie dogs, while no known naturally occurring, clinically relevant viral diseases exist for gerbils and sugar gliders. This article is intended to aid the clinician in identifying viral infections in small mammals and to help determine the significance each virus has during clinical disease.     

Effect of consumption of organically and conventionally produced apples on antioxidant activity and DNA damage in humans

The present study was performed to compare the effects on antioxidant activity and on DNA damage of organic and conventionally produced apples grown under controlled conditions in human peripheral blood lymphocytes. Six healthy volunteers consumed either organically or conventionally grown apples (Golden Delicious, 1000 g) from two neighboring commercial farms in a double-blinded, randomized, cross-over study. The average content of total identified and quantified polyphenols in the organically and conventionally produced apples was 308 and 321 microg/g fresh weight, respectively. No statistically significant differences in the sum of phenolic compounds or in either of the polyphenol classes were found between the agricultural methods. Consumption of neither organically nor conventionally grown apples caused any changes in antioxidant capacity of low-density lipoproteins (lag time test), endogenous DNA strand breaks, Fpg protein-sensitive sites, or capacity to protect DNA against damage caused by hydrogen peroxide. However, a statistically significant decrease in the levels of endonuclease III sensitive sites and an increased capacity to protect DNA against damage induced by iron chloride were determined 24 h after consumption in both groups of either organic or conventionally grown apples, indicating the similar antigenotoxic potential of both organically and conventionally grown apples.     

Correction to: Molecular analysis indicates high levels of carabid weed seed consumption in cereal fields across Central Europe

Journal of Pest Science -     

Pattern of Kirtland's warbler occurrence in relation to the landscape structure of its summer habitat in northern Lower Michigan

Studies of the endangered Kirtland's warbler in relation to landscape ecosystems were conducted from 1986–1988 on a large wildfire-burn surrounding Mack Lake in southeastern Oscoda County, Michigan. A landscape ecosystem approach was used to distinguish low- and high-elevation segments of the landscape, as well as 11 local ecosystem types. The ecosystems were distinguished by physiography, microclimate, soil, and vegetation. The early occurrence of the warblers was strongly related to landscape structure, i.e., to the broad low- and high-elevation areas and the local ecosystem types within them. Territories of male warblers were observed in 5 of the 11 ecosystems. The five ecosystem types where warblers were observed were characterized by (1) a physiography of level or rolling terrain; (2) soil series of Grayling, Graycalm, Montcalm, or Rubicon; (3) uplands with relatively warm temperature during the breeding season; (4) vegetation dominated by low sweet blueberry, bearberry, wintergreen, northern pin oak, blue stem grasses, and hair cap moss; and (5) canopy of relatively tall, dense, and patchy jack pine and oak. Landscape structure appears to be an important factor affecting the occurrence of the warbler in its summer habitat in northern Lower Michigan.     

A journey in and out of American agriculture. Reflections on Debt and Dispossession by Kathryn Marie Dudley (University of Chicago Press, 2000)

I was optimistic of a new beginning in an open society when I came to America in 1999. Since then, I have indeed benefited from many aspects of American life. I have learned a lot – especially through my experience with small farms and farmers. But now, it's time to move on. And it was reading Debt and Dispossession, a book about American agriculture and human values, that crystallized in me why I wanted to leave. By telling the story of the 1980s farm crisis through the words of the residents of a Minnesota town, the book prizes open many of the contradictions of American society. The 1970s were boom times for mid-western farms; farmers took advantage of easy farm credit to finance expansion. By the 1980s, the boom burst and slump loomed. Lenders wanted their money back and thousands of farmers were dispossessed. Debt and Dispossession probes beneath the surface of a community apparently united in protest against the dispossessions. Underneath, it finds a tangled picture of a society at war with itself, pitting farmer against farmer in a fratricidal struggle. The book let me glimpse the paradox of American individualism, all-American contradictions centering on government and consumerism, frugality and morality. Just like my experience of American agriculture and farmers as a whole, Debt and Dispossession helped me see the best side of America, but also revealed the fragility of life in a one-on-one society.     

Relative importance of management vs. design for implementation of large-scale ecological networks

Ecological networks (ENs) are used to mitigate landscape-scale habitat loss, and are managed and designed to conserve regional biodiversity. In our study region in southern Africa, ENs of isolated grassland remnants are specifically set aside and managed for conservation, and are complemented by corridor-like power line servitudes which are maintained by regular mowing. Using grasshoppers, a sensitive and reliable bioindicator taxon, we determine whether ENs effectively conserve biodiversity. We used cluster analysis and variation partitioning to select the best subset of environmental variables which explained the patterns of species composition. We then compared the relative importance of environmental variables grouped by the scale of their influence: local-scale variables affected by management practices vs. landscape-scale variables affected by design of ENs. Management was consistently and significantly 2–5 times more influential than design in determining grasshopper assemblages within ENs and servitudes. Servitudes had a higher proportion of bare ground, lower proportion of tall grasses and higher abundance of grasshoppers relative to ENs. Three grasshopper species were strongly associated with servitudes and exhibited traits consistent with early colonizers. As management actions are primarily responsible for vegetation succession, the use of ENs for conservation efforts should first focus on appropriate management strategies, such as fire regime and grass height management before altering the landscape structure (e.g. increasing connectivity or enlarging patches). The conservation implications of these results are that, if ENs are managed and designed for heterogeneity and to simulate multiple successional stages, they may be beneficial for biodiversity conservation.     

LC-MS/MS quantification of sulforaphane and indole-3-carbinol metabolites in human plasma and urine after dietary intake of selenium-fortified broccoli

This study aimed at developing a sensitive LC-MS/MS method for the quantification of sulforaphane (SFN) and indole-3-carbinol metabolites in plasma and urine after dietary intake of regular and selenium-fertilized broccoli using stable isotope dilution analysis. In a three-armed, placebo-controlled, randomized human intervention study with 76 healthy volunteers, 200 g of regular (485 μg of total glucosinolates and <0.01 μg of selenium per gram fresh weight) or selenium-fertilized broccoli (589 μg of total glucosinolates and 0.25 μg of selenium per gram fresh weight) was administered daily for 4 weeks. Glucoraphanin and glucobrassicin metabolites quantified in plasma and urine were SFN-glutathione, SFN-cysteine, SFN-cysteinylglycine, SFN-acetylcysteine, and indole-3-carboxaldehyde, indole-3-carboxylic acid, and ascorbigen, respectively. Dietary intake of selenium-fertilized broccoli increased serum selenium concentration analyzed by means of atomic absorption spectroscopy by up to 25% (p < 0.001), but affected neither glucosinolate concentrations in broccoli nor their metabolite concentrations in plasma and urine compared to regular broccoli.     

Versuche mit Herbiziden in Gemeiner Ringelblume (Calendula officinalis L.) in Sachsen-Anhalt und Thüringen

Between 2000 and 2005 12 experiments with 18 herbicides were carried out in marigold in experimental stations and on marigold fields of Thuringian farms. The main objective of the tests was to get the necessary data for the authorization procedure according to the regulations of §?18 a PflSchG. Marigold plants are very susceptible against some herbicides Betanal Progress, Goltix Compact + ?l, Kontakt 320 SC, Lentagran WP und Stefes IPU. These herbicides and cause severe damages on this culture. The use oft the herbicides Bandur, BASTA and further herbicides with the active ingredient Glufosinat was authorized for the application in marigold according the regulations of §?18 a PflSchG in the past. The herbicides Devrinol FL, Fusilade MAX, Goltix 700 SC, Roundup UltraMAX und Targa Super can be used in artichoke according the regulations of §?18 b PflSchG. These herbicides aren??t enough for the chemical control of weeds likeEchinochloa spec.,Galinsoga spec., Polygonum spec. in marigold. In addition to the application of the herbicides mechanical measures are necessary.     

A proposal of clinical breakpoints for amoxicillin applicable to porcine respiratory tract pathogens

In the present position paper, an attempt was made to establish clinical breakpoints of amoxicillin to classify porcine respiratory tract pathogens as susceptible, intermediate or resistant based on their minimum inhibitory concentrations of amoxicillin. For this, a thorough review of the published literature with regard to swine-specific pharmacological data (including dosages of amoxicillin applied and routes of administration used), clinical efficacy, and in vitro susceptibility of the target pathogens was performed. Based on the comparative analysis of the results, the working group "Antibiotic Resistance" of the German Veterinary Medical Society (DVG) proposed to classify porcine respiratory tract pathogens that show MIC values of amoxicillin of < or =0.5microg/ml as "susceptible", those with MICs of 1microg/ml as "intermediate", and those with MICs of > or =2microg/ml as "resistant".