A stretchable form of single-crystal silicon for high-performance electronics on rubber substrates

We have produced a stretchable form of silicon that consists of submicrometer single-crystal elements structured into shapes with microscale, periodic, wavelike geometries. When supported by an elastomeric substrate, this "wavy" silicon can be reversibly stretched and compressed to large levels of strain without damaging the silicon. The amplitudes and periods of the waves change to accommodate these deformations, thereby avoiding substantial strains in the silicon itself. Dielectrics, patterns of dopants, electrodes, and other elements directly integrated with the silicon yield fully formed, high-performance "wavy" metal oxide semiconductor field-effect transistors, p-n diodes, and other devices for electronic circuits that can be stretched or compressed to similarly large levels of strain.     

Resistance to Streptococcus iniae and its genetic associations with traits of economic importance in Asian seabass (Lates calcarifer)

Streptococcus iniae is one of the most serious aquatic pathogens, causing significant economic losses in marine and freshwater species, including Asian seabass (Lates calcarifer). Controlling this gram‐positive bacterial pathogen has been an issue in aquaculture systems, due to the combined effects of aquaculture intensification and climatic impacts. To date, there have not been any genetic parameter estimates for S. iniae resistance in Asian seabass. The main aim of this study was to examine genetic variation in S. iniae resistance and its genetic correlations with growth and cannibalism in Asian seabass families produced from a breeding programme for high growth in 2016 and 2017. The study included a total of 5,835 individual fish that were offspring of 41 sires and 60 dams (31 half‐sib and 34 full‐sib families). The experimental fish were challenged by intraperitoneal injection with a volume containing 10⁵ CFU (colony‐forming unit)/fish. Resistance to S. iniae was measured as survival rate at 6 hr, 3, 5, 7, 10 and 15 days post‐challenge test. There were significant variations in S. iniae resistance among families at different observation periods (ranging from 24.4% to 80%). Restricted maximum‐likelihood method and mixed model analysis were applied to estimate heritability for S. iniae resistance. The heritability for S. iniae resistance ranged from 7% to 18% across different statistical models used. The common full‐sib effects accounted for 0.1%–2% of the total variation in resistance to S. iniae. Genetic correlations of the S. iniae resistance at 6 hr and 3 days with later post‐challenge test periods were low to moderate. However, these estimates for S. iniae resistance between successive measurement times (5, 7, 10 and 15 days) were high and close to 1. The genetic correlations of resistance with body weights at 180, 270 and 360 days post‐hatch were not significant as well with cannibalism. It is concluded that there is substantial additive genetic variation in resistance to S. iniae, suggesting there is potential for genetic improvement of Asian seabass for resistance to S. iniae through selective breeding.     

A modeling approach for assessing rice cropping cycle affected by flooding,salinity intrusion,and monsoon rains in the Mekong Delta,Vietnam

We developed a crop scheduling model for rice cultivation in the Vietnam Mekong Delta (VMD), focusing on the adaptive behavior of crop planning to various water resource constraints. In addition, we also examined the effects of environmental change on rice cultivation in the last decade. In the VMD, multiple rice cropping is practiced under a variety of adverse water conditions, including flooding, salinity intrusion, and irregular monsoon rains. These environmental changes influence the durations of growing seasons and the number of crops per year, resulting in changes in productivity. To validate the performance of the model, we compared model estimates for the heading date and changes in leaf area index at nine sites with estimates of these parameters derived from MODIS satellite time series data for the period 2002–2006. The root mean square errors of heading date between the modeled and satellite data in the upper, middle, and coastal regions of the delta were 17.6, 11.2, and 13.0 days, respectively. Based on the model, we examined case studies to assess the changes in cropping cycles and crop failures in the VMD due to extreme flooding in 2000 and salinity intrusion in 2004 by applying evaluation indices defined by available period for cultivation (APC) and safe margin for cropping (SMC) which is defined as the marginal time between APC and the period required for cultivation. Findings of case studies suggested that a small difference in the SMC of the cropping pattern is critical to the stability and productive capacity of the rice crop.     

Genetic characterization of coconut (Cocos nucifera L.) varieties conserved in Vietnam through SCoT marker-based polymorphisms

Genetic Resources and Crop Evolution - Coconut (Cocos nucifera L.) production sustains millions of smallholder farmers and their families around the globe, and also powers a thriving industry of...     

Assessment of genetic variability of resistance to gastrointestinal nematode parasites in Creole goats in the humid tropics

Goat production is widespread in the tropics. Goats are very susceptible to gastrointestinal nematode infection, but there is less evidence of their genetic resistance. Genetic resistance of Creole goats to gastrointestinal nematodes has been studied at Guadeloupe in the French West Indies since 1995. The objective of this research was to investigate genetic variation for resistance to gastrointestinal nematode infection, in order to introduce this trait into breeding schemes. Genetic variability was assessed within a Creole experimental flock. Forty-nine sire groups were characterized at weaning and 55 during fattening after weaning. Kids were naturally infected, mainly by Haemonchus contortus and Trichostrongylus colubriformis. Fecal egg counts were determined once at weaning and every 6 and 7 wk after drenching during fattening. Blood samples were collected every 7 wk during fattening for determination of packed cell volume. Live weights were recorded at weaning and at the beginning and middle of every infection period during fattening. Genetic parameters were estimated using the REML for multivariate animal models. The heritability estimate for transformed fecal egg count was 0.37+/-0.06 at weaning. During fattening, it increased from 0.14+/-0.05 at 4 mo to 0.33+/-0.06 at 10 mo. Heritabilities of packed cell volume ranged from 0.10 to 0.33. At weaning, maternal heritability of fecal egg count reached 0.26 and direct heritability 0.20. After 6 mo of age, maternal effects were found to be unimportant for fecal egg count and packed cell volume. Live weights presented significant genetic variability. Genetic relationships between fecal egg counts and live weight in infected pastures were never significant. Genetic correlations between packed cell volume and live weight decreased from 0.47 to 0.10 from weaning to 10 mo of age. These results demonstrated the feasibility of breeding for improved resistance to nematodes in Creole kids.     

Effects of Fresh Cassava Tops on Rumen Environment Parameters,Thyroid Gland Hormones and Liver Enzymes of Local Yellow Cattle Fed Urea-treated Fresh Rice Straw

In a 4 x 4 Latin square design study, four rumen-cannulated local yellow cattle, average weight 330 kg, were fed urea-treated fresh rice straw (UFRS) ad libitum and given 1 kg cassava root meal daily as basal diet in each 30-day trial period. Four treatment levels of crude protein of fresh cassava tops (FCT) were supplied: 0 (FCT0), 50 (FCT50), 100 (FCT100) and 150 g (FCT150) crude protein per 100 kg body weight. The results showed a continuous decrease in dry matter intake (DMI) of UFRS with increasing level of FCT supplementation (p<0.001). Total DMI for treatments FCT150, FCT100, FCT50 and FCT0 were 2.66, 2.42, 2.23 and 2.05 kg dry matter per 100 kg live weight per day, respectively. Increasing levels of FCT supplementation increased the concentration of total volatile fatty acids (p<0.05) and ammonia (p<0.001) and resulted in a decrease in pH (p<0.05). Rumen protozoa population varied widely but was significantly lower with increasing FCT supplementation (p<0.001), while rumen bacteria population was higher (p<0.05). Overall, average plasma triiodothyronine and thyroxine concentrations in the four groups were respectively 1.36, 0.94, 0.91, 0.80 ng/ml (p<0.01) and 60.9, 48.7, 45.2, 42.5 ng/ml (p<0.001). There were non-significant differences in alanine aminotransferase and aspartate aminotransferase concentrations among the treatments.     

Plant pathogen culture collections: it takes a village to preserve these resources vital to the advancement of agricultural security and plant pathology

ABSTRACT Plant pathogen culture collections are essential resources in our fight against plant disease and for connecting discoveries of the present with established knowledge of the past. However, available infrastructure in support of culture collections is in serious need of improvement, and we continually face the risk of losing many of these collections. As novel and reemerging plant pathogens threaten agriculture, their timely identification and monitoring depends on rapid access to cultures representing the known diversity of plant pathogens along with genotypic, phenotypic, and epidemiological data associated with them. Archiving such data in a format that can be easily accessed and searched is essential for rapid assessment of potential risk and can help track the change and movement of pathogens. The underexplored pathogen diversity in nature further underscores the importance of cataloguing pathogen cultures. Realizing the potential of pathogen genomics as a foundation for developing effective disease control also hinges on how effectively we use the sequenced isolate as a reference to understand the genetic and phenotypic diversity within a pathogen species. In this letter, we propose a number of measures for improving pathogen culture collections.     

Fucoxanthin Suppresses Osteoclastogenesis via Modulation of MAP Kinase and Nrf2 Signaling

Fucoxanthin (FX), a natural carotenoid present in edible brown seaweed, is known for its therapeutic potential in various diseases, including bone disease. However, its underlying regulatory mechanisms in osteoclastogenesis remain unclear. In this study, we investigated the effect of FX on osteoclast differentiation and its regulatory signaling pathway. In vitro studies were performed using osteoclast-like RAW264.7 cells stimulated with the soluble receptor activator of nuclear factor-κB ligand or tumor necrosis factor-alpha/interleukin-6. FX treatment significantly inhibited osteoclast differentiation and bone resorption ability, and downregulated the expression of osteoclast-specific markers such as nuclear factor of activated T cells 1, dendritic cell-specific seven transmembrane protein, and matrix metallopeptidase 9. Intracellular signaling pathway analysis revealed that FX specifically decreased the activation of the extracellular signal-regulated kinase and p38 kinase, and increased the nuclear translocation of phosphonuclear factor erythroid 2-related factor 2 (Nrf2). Our results suggest that FX regulates the expression of mitogen-activated protein kinases and Nrf2. Therefore, FX is a potential therapeutic agent for osteoclast-related skeletal disorders including osteoporosis and rheumatoid arthritis.