家兔硫酸钡浆、硫酸钡粉和碘油x线支气管造影的病理学观察

本试验首次在符合实际造影要求的家兔 x 线支气管造影实验模型上,对40只家兔硫酸钡浆、硫酸钡粉和碘油支气管造影后的病生理反应进行了为期60天的比较观察。试验证明,硫酸钡较碘油造影后清除快、沉积少,对肺组织刺激性小,是一种惰性无毒、正确应用时不影响机体的造影剂。又鉴于硫酸钡价廉,造影像质量高等优点,建议可将其选作兽医临床 x 线支气管造影用剂。     

BARIUM SULFATE BRONCHOGRAPHY IN HORSES

Barium sulfate bronchograms were performed on four 454-kg (1000-lb), adult, mixedbreed horses. Approximately 100 ml of 100% w/v premixed barium sulfate suspension was insufflated into a caudodorsal portion of one lung. Excellent bronchograms were obtained through six generations of bronchial divisions. Bronchograms of diagnostic quality were present for at least 30 minutes. Radiographs at 24 hours showed that most of the barium had been removed from the lung. At 48 hours, tiny barium nodules were essentially all that remained. One hundred and thirty milliliters of barium sulfate initially resulted in overfilling of the bronchial tree and prolonged retention of the contrast medium. Six weeks after bronchography, histopathologic examination of the perfused fixed lungs of two horses showed a very mild inflammatory response to the barium. One of the four horses received two barium sulfate bronchograms. This horse was observed and found to be free of any side effects for 15 months after the second bronchogram.