千岛湖国家森林公园针叶林阔叶化改造技术探讨

通过对千岛湖国家森林公园森林植被的调查,分析了森林结构存在的主要问题,并就针叶林阔叶化改造相关技术措施进行了探讨.     

乌头属药用植物研究进展

对乌头属植物的分布与种类、药用价值、化学成分、药理作用和毒性等方面进行综述,为乌头属植物的开发利用提供参考。     

Effect of Busui Shengxue Granule (补髓生血颗粒) on Chronic Aplastic Anemia Patients' Hematopoietic Adhesion Molecule VLA-6/CD49f and Its Ligand Laminin

Objective:To observe the effect of Busui Shengxue Granule (补髓生血颗粒Herbal granule for replenishing marrow to produce blood) on chronic aplastic anemia (CAA) patients' integrin a 6 (VLA-6/CD49f) and...     

太阳能提灌站的构成及其应用

介绍了太阳能提灌站的构成,并对其应用实例进行分析,以期为太阳能提灌站的应用提供参考。     

糖尿病前期中医体质及相关指标的研究

目的探讨糖尿病前期(IGR)中医体质及与相关指标的关系。方法用前瞻性研究方法,采集517例IGR患者信息,进行中医体质辨识和相关指标的分析。结果①517例IGR人群中,单一体质类型者、二种体质类型相兼者、三种体质类型相兼者分别占25.8%、66.5%、7.7%;前3位的体质类型分别是痰湿兼湿热质、痰湿兼气虚质、湿热质,共占64.8%。②痰湿兼湿热质、痰湿兼气虚质、湿热质体质量指数(BMI)、腰臀比(WHR)、血脂TC、TG、LDL-C显著高于其他体质组,差异有统计学意义(P<0.01)。结论①IGR人群体质可表现为单一体质,也可表现为复合型体质,其中以痰湿兼湿热质、痰湿兼气虚质、湿热质为主,提示痰湿和湿热是IGR人群的重要因素。②BMI、WHR、血脂TC、TG、LDL-C是IGR痰湿和湿热体质的辨识和疗效判断的参考指标。     

Expression of EPCAM,CD44 and CD24 in gastric cancer tissues and its clinical significance

AIM: To evaluate the relationship between epithelial cell adhesion molecule (EPCAM)/cluster of differentiation 44 (CD44)/cluster of differentiation 24 (CD24) expression and the clinicopathological characteristics/prognosis in 95 gastric cancer patients. METHODS: The expression levels of EPCAM, CD44 and CD24 were detected using the two-step method of immunohistochemistry in 95 gastric cancer patients who underwent surgical excision and were pathologically diagnosed as gastric cancer. RESULTS: There were 56 EPCAM-positive patients (58.95%), 41 CD44-positive patients (43.16%) and 56 CD24-positive patients (58.95%). Thirty patients were both EPCAM and CD44 positive (31.58%), 45 patients were both EPCAM and CD24 positive (47.37%), 32 patients were both CD44 and CD24 positive (33.68%), and 25 patients were EPCAM, CD44 and CD24 positive (26.32%). EPCAM expression was correlated with age, depth of tumor infiltration and WHO histological classification. CD44 expression was correlated with BORRMANN and WHO histological classification as well as CEA value. CD24 expression was correlated with the depth of infiltration, location of the tumor, WHO histological classification and viscera invasion. All positive expression of EPCAM, CD44 and CD24 was correlated with the depth of infiltration, location of the tumor and WHO histological classification (P<0.05). The difference of survival rate between EPCAM positive group and negative group was observed, and the CD44 positive group and negative group had the same result (P<0.05 and P<0.01, respectively). The difference of survival rate between EPCAM⁺CD44⁺CD24⁺ group and EPCAM^-CD44^-CD24^- group was statistically significant (P<0.05). The difference of survival rate between EPCAM^-CD44⁺CD24⁺ group and EPCAM^-CD44^-CD24^- group was also significant (P<0.05). CONCLUSION: The positive rates of EPCAM, CD44 and CD24 expression are high in gastric cancer tissues and these 3 proteins can be used as primary screening targets.     

水生动物10种非特异性免疫分子的研究进展

水生动物的非特异性免疫系统在其自身抗病作用中较特异性免疫系统发挥更大作用.从水生动物免疫系统的防御功能分别综述了主要组织相容性复合体、补体、干扰素、凝集素、白细胞介素、抗菌肽、溶菌酶、转铁蛋白、鱼精蛋白以及金属硫蛋白等10种水生动物非特异性免疫分子的研究进展.     

血清可溶性细胞间粘附分子在大肠癌患者组织中的检测及其意义

目的:探讨血清可溶性细胞间粘附分子1(sICAM-1)的检测在大肠癌患者中的临床意义。方法:采用双抗体夹心ELISA法检测50例大肠癌、30例大肠良性病变及30例健康体检者血清sICAM-1水平,并比较大肠癌患者术前、术后,转移、无转移sICAM-1水平变化。结果:大肠癌患者血清sICAM-1水平明显高于良性病变患者及正常人(P<0.01);大肠癌患者术后血清sICAM-1水平较术前明显下降(P<0.01);有转移的大肠癌患者血清sICAM-1水平高于无转移的患者(P<0.01)。结论:血清sICAM-1水平与大肠癌的发生、发展密切相关,可作为大肠癌新的检测指标之一。     

L-选择素分子结构及功能的研究进展

近 1 0年来 ,由于分子生物学及相关学科的理论和技术的飞速发展 ,使得对L 选择素的分子结构、分子功能的研究更加深入。就其分子结构而言目前已经完全清楚 ,而功能与其相应的问题仍在研究和探索之中。作为受体的选择素 ,其功能的实现是在其与相应的配体结合之后。表达与调节是在细胞因子、炎症介质以及其他因素的作用下 ,细胞表面黏附分子表达的水平和构型可以发生改变 ,以调节免疫平衡。L 选择素通过白细胞表面的Ca2 依赖的凝集素结构域和胞内小片段激活酪氨酸酶p56lck和ras的信号途径进行跨膜信号转导。活化依赖和活化独立的脱落、生理和病理意义及基因改造对功能的影响等方面目前仍在进一步的研究之中     

芝麻核心种质株高构成相关性状的遗传变异及关联定位

以我国216份芝麻核心种质为材料,分析芝麻株高及其构成相关性状的变异、相互关系等,利用79对EST-SSR、AFLP和SRAP引物对供试材料基因组进行检测并进行标记-性状关联分析,检测群体中与株高构成性状相关的DNA变异位点.结果表明,株高及其构成性状的变异均呈现连续变化,变异丰富,变异系数均在10％以上;相关性分析和多元回归拟合株高及其构成因素间的关系表明,主茎始蒴高度、主茎果轴长度是影响株高差异的主要因素.利用GLM(Q)和MLM(Q+K)模型共检测到34个变异位点同时与供试群体两年的株高构成显著关联,对表型变异解释率在1.89％～5.29％,平均为2.82％,其中与主茎始蒴高度显著关联的标记位点M20E12-3被2种模型均检测到.此外,研究发现株高构成因素受基因型、环境和两者互作影响,且均达到极显著水平.