Closed system anaesthesia in dogs using liquid sevoflurane injection; evaluation of the square-root-of-time model and the influence of CO2 absorbent

Objective To determine whether predictable alveolar concentrations of sevoflurane are reliably produced in dogs when liquid sevoflurane is injected into closed circuit breathing systems, as calculated by Lowe's square‐root‐of‐time anaesthetic uptake model, and to confirm the validity of the model using soda lime and calcium hydroxide lime. Study design Prospective clinical study. Animals Eleven healthy dogs with a mean body mass of 34 ± 9 kg scheduled for pelvic limb orthopaedic surgery. Materials and methods Following pre‐anaesthetic medication, anaesthesia was induced with propofol and maintained with sevoflurane in a closed circle system. Epidural anaesthesia was performed with morphine and bupivacaine. Liquid sevoflurane was injected into the circuit by syringe, using dosages and time intervals derived from Lowe's square‐root‐of‐time anaesthetic uptake model. The target alveolar concentration chosen was 1.1 × MAC (2.6% end‐tidal sevoflurane). Either soda lime (group S; n = 6) or calcium hydroxide lime (Amsorb; group A; n = 5) were used for CO₂ absorption. Sevoflurane concentration and the respiratory gas composition were measured with an infrared gas analyser. Results End‐tidal sevoflurane concentrations were close to the predicted value of 2.6% at 9 minutes (2.53 ± 0.1% group S; 2.60 ± 0.26% group A) and 16 minutes (2.55 ± 0.30 group S; 2.52 ± 0.28% group A) but declined thereafter to reach 50% (group S) and 64% (group A) of the predicted value at 121 minutes. There was a constant trend towards higher end‐tidal sevoflurane concentrations in group A but the difference was not statistically significant. Conclusions The square‐root‐of‐time model leads to significantly lower alveolar concentrations than expected, suggesting that the rate of sevoflurane uptake in dogs declines less rapidly than predicted. The use of Amsorb tends to reduce the deviation from predicted concentrations. Clinical relevance The model used in this study provided only an approximate guide to the volume of liquid sevoflurane required. Consequently, the definitive dose schedule must be based on measured anaesthetic concentrations and clinical monitoring.     

西藏东南部原始森林夏-秋季节鸡类的栖息地利用

本文报道了1995年夏-秋季节西藏东南部原始森林鸡类栖息地的利用方式.记录有7个物种,这些物种大多喜欢在阳坡环境,而回避相对潮湿的阴坡环境.在这一鸡类群落中,白马鸡(Crossoptilon crossoptilon)与藏马鸡(C.harmani)的杂交类型在数量上是最丰富的,其次是血雉(Ithaginis cruentus)和斑尾榛鸡(Bonasa sewerzowi).随后于2001年的调查表明,由于地处偏僻,这些鸡类依然没有遭受人类狩猎和栖息地干扰的影响.     

The leaf-litter earthworm fauna (Annelida: Oligochaeta) of forests in Limpopo Province,South Africa: diversity,communities and conservation

A qualitative survey of the leaf-litter earthworm fauna of 11 selected indigenous forests in Limpopo Province, South Africa, was conducted to identify the species present, to describe the communities and to assess the relationship between indigenous and exotic species. A total of 8185 individuals from 17 species (five indigenous and 12 exotic species) were recorded. The average earthworm community comprised fewer than five species, but up to seven species were sampled from a single forest. Four of the species recorded are national (one species), regional (one species) or local (two species) endemics. Because these species are not known to live elsewhere, the protection of Limpopo Province forests is critical to their survival. The majority (71%) of the earthworm species sampled was exotic, and differences between exotic and indigenous species richness in forests were mostly significant. At the two spatial scales examined (20 m2 and individual forest) there is no evidence of an association between exotic and indigenous species richness. However, we cannot assume that exotic earthworms do not impact the forest ecosystem.     

过程性考核在《细胞生物学》课程教学中的应用

过程性考核是在课程实施的过程中对学生的学习进行评价的方式,强调对学生学习综合知识与能力素养的考核,能够克服一次性期末闭卷考试的不足.细胞生物学课程过程性考核根据教学内容分阶段采取多样化的考核方式,不仅可以促进学生分阶段完成学习任务,使任课教师及时了解学生的学习效果,而且还具有激发学生的学习主动性、引领学生自主学习等作用...     

论生物多样性与建设海南国际旅游岛的关系

经过多年的研究和实践,人们已深刻地认识到,海南省的发展战略应该积极发展服务型、开放型和生态型经济,形成以旅游业为龙头、以现代服务业为主导的特色经济结构。显然要实现这个宏伟的目标,生物多样性的保护和持续利用就是最根本和最关键的问题。如果作为生态旅游基本资源的季节性雨林、红树林、海洋生物资源和农业生物多样性被毁,一切都将是一纸空文。本文就拟简略地探讨一下有关这些方面的问题,并提出一些建议供有关方面参考。     

基于随机森林的高寒草地地上生物量高光谱估算

草地地上生物量(Aboveground biomass,AGB)是衡量草地生产力的关键因素,准确测定草地AGB具有重要意义.高光谱因具有时效性强、不破坏草地等特点被广泛用于草地生理生态指标的测定.本研究提取和计算了海北试验站高寒草地冠层的原始光谱(Original spectrum,OR)反射率、一阶微分光谱(Firs...     

Including an additional systematic environmental effect within a generation in an evaluation model improves accuracy of prediction of breeding values in a closed herd of pigs

The present study evaluated the advantage of mixed‐model techniques over a selection index under different magnitudes of an additional systematic environmental effect (ASEE) in terms of accuracy of prediction and expected genetic gain. The data attempted to simulate a closed herd in a pig breeding program. The base population (G₀) consisted of 10 males and 50 females. Six generations (G₀ to G₅) were selected by using a selection index of three traits without overlapping. Additional systematic environmental constants with four levels in a generation were assigned from a uniform distribution at different ranges. Breeding values of animals in the last generation (G₅) were estimated on the basis of an index of individual phenotype (SI‐U), SI‐U adjusted for ASEE using a least‐squares mean (SI‐A), best linear unbiased prediction using an animal model excluding ASEE (AM‐E), and an animal model including ASEE (AM‐I). Accuracy of prediction and expected genetic gain were larger by the animal model than by the selection index, even if heritability of the traits selected was high and ASEE was set to zero. When ASEE was zero, the accuracy of prediction and expected genetic gain given by SI‐U and AM‐I were similar to those given by SI‐A and AM‐E, respectively. However, the differences in accuracy and expected gain between SI‐U and AI‐A and between AM‐I and AM‐E increased as the range of ASEE increased. It was concluded that selection based on an animal model was more effective than index selection, even if the herd environment was uniform and traits with high heritability were selected, and that it should be always included in an evaluation model, however slight any systematic environmental effect may be in a closed herd.     

内蒙古大兴安岭林区发展草地畜牧业潜力分析与对策

内蒙古大兴安岭林区草地资源较为丰富，发展林区草地畜牧业的潜力较大，但该地区草地资源和利用不均衡，有的草地严重超载，造成草场退化；而有此可利用草地尚未被充分利用，本文着重对充分利用的区域和自然条件优势及丰富的草地资源，发展林区畜牧业，建立绿色畜产品基地的潜力和对策，进行了切实可行的分析。     

川西干旱河谷林草植被建设科学考察报告

阐述了川西干旱河谷现有治理状况 ,存在问题 ,提出了治理该区的措施和发展农业经济的建议。     

哀牢山壳斗科三种蜜源植物资源的初步研究

壳斗科植物具有丰富花蜜和花粉.2007年4～7月,对云南哀牢山中山湿性常绿阔叶林壳斗科蜜源植物开发利用的潜力进行了初步研究.在该季节,中华蜜蜂可利用的壳斗科植物主要有木果石栎、景东石栎和腾冲栲.3种植物的花期均为50天左右.放置在原始森林林缘蜂群的取蜜量明显高于放置在原始森林内和附近次生林的蜂群.一群放置在林缘、群势为5标准框的中华蜜蜂蜂群,一个花期可以取蜂蜜约5 kg.