Orbital extraskeletal osteosarcoma following enucleation in a cat: a case report

Objective We present a unique case of a feline orbital extraskeletal osteosarcoma that developed 5 years post‐enucleation. History In 2002, an ophthalmologist enucleated the left eye of a 2‐year‐old neutered male DSH and submitted it to the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW). COPLOW diagnosed the left eye with feline diffuse iris melanoma. In June 2007, the cat presented to another veterinarian for moderate swelling of the enucleation site. Palpation suggested a firm mass along the lateral orbital rim and an exploratory orbitotomy revealed a cyst with a mass adhered to it and the ventrolateral orbital rim. The cyst and mass were excised by the veterinarian and submitted to COPLOW. COPLOW diagnosed the tissue as an orbital conjunctival inclusion cyst and an acquired orbital osteosarcoma. Conclusions Following the enucleation, retained conjunctival epithelium became embedded in the connective tissue of the orbit and caused a cyst to develop. The cyst wall consisted of a myofibroblastic collagen‐rich matrix and acted as a nidus of chronic irritation and tumor growth. This orbital osteosarcoma resembles feline vaccine‐associated sarcomas (VAS), feline post‐traumatic ocular sarcomas, and microchip‐associated sarcomas in terms of it histopathology and its hypothesized pathogenesis related to exposure to antigenic material such as implanted epithelium, lens protein, vaccine components, and microchips as foreign bodies.     

A simplified surgical technique for correction of orbital adipose prolapse in the horse

A Quarter Horse gelding underwent standing surgical correction of an orbital adipose prolapse through a subconjunctival approach removing the prolapsed fat without use of electrocautery or closure of the conjunctiva. This technique provided an acceptable long‐term cosmetic outcome. There was no recurrence of orbital adipose prolapse up to 15 months post operatively. The surgical procedure performed in this case is a simple technique, which could be performed in the field under sedation and local anaesthesia.     

Surgical correction of severe strabismus and enophthalmos secondary to zygomatic arch fracture in a dog

A grossly displaced segmental zygomatic arch fracture with marked ventro-lateral deviation of the left globe was diagnosed in a 3-month-old male German Shepherd dog following a bite injury. The fracture was approached via a modified lateral orbitotomy and a fragment of the lacrimal bone removed. The rostral portion of the fracture was stabilized with a 5-hole 2.0 dynamic compression plate bone plate. The surgical correction achieved sufficient skeletal fixation for proper anatomical reduction of the globe and excellent cosmetic and functional outcomes.     

Comparison of orbital prosthesis motility following enucleation or evisceration with sclerotomy with or without a motility coupling post in dogs

Objective  To evaluate motility of silicone orbital implants and corneoscleral prostheses, with and without use of a motility coupling post (MCP) in dogs.
Animals studied  Eighteen mixed-breed dogs.
Procedures  The motility of an orbital silicone implant and corneoscleral prosthesis after enucleation ( n  = 6), evisceration ( n  = 6), or use of a MCP with evisceration ( n  = 6) in dogs were compared. One eye from each dog had surgery whereas the opposite eye was used as a control. Clinical evaluations were performed three times a week. Histopathology of the orbital tissues was performed 8 and 12 weeks after surgery.
Results  Implant motility in dogs with evisceration (vertical movement [VM] 8.04 ± 2.13; horizontal movement [HM] 11 ± 3.05) and evisceration with MCP (VM 9.61 ± 1.59); HM was significantly greater than the enucleation group (VM 0.51 ± 0.5; HM 1.22 ± 0.68) ( P <  0.01). Prosthetic motility in dogs with evisceration with MCP was significantly greater than in dogs with evisceration; dogs with evisceration had significantly greater motility than dogs with enucleation ( P <  0.01). No postoperative complications were observed in any of the groups. No significant abnormalities were noted on histopathology.
Conclusions  MCP placement in silicone orbital implants significantly enhanced the prosthetic motility in dogs. This study supports the use of MCP in silicone orbital implants to enhance corneoscleral prosthesis motility and cosmetics in dogs.     

The molecular structure and chemical bond properties of dimethylphenylsilanol studied by DFT/B3LYP

Dimethylphenylsilanol is easily refined into high pure silicon, but there is a lack of experimental data of its chemical bonding properties. The optimized molecular structure parameters of dimethylphenylsilanol are calculated through density functional theory (DFT) method with B3LYP/6 311++G** basis sets. Then, the molecular chemical bonding properties are investigated with the natural atomic obtain analysis, the frontier orbital analysis and the overlap population analysis under the natural bond orbital (NBO) theory. It is showed that the O-H bond isn’t affected when the phenyl and the methyl are joined into molecule, but the molecular energy and dipole moment are reduced, so as to make molecule more stable. The Si-C bond between silicon atom and the phenyl is weak. But the bond strength of Si-O is strengthened a little. The O-H bond is the weakest one in the molecular chemical bond. In addition, the electron on the carbon atom in the phenyl is prone to nonlocalizing primarily. The lone pair electron of oxygen atom transferring to the anti bonding orbital between silicon and carbon atoms weakens Si-C bond to some sort. So the gap of the theoretical principle of chemical bonding properties of C6H5(CH3)2SiOH can be filled and the basic theory of chemical reaction of C6H5(CH3)2SiOH is obtained.     

基于π值法则的油松人工林稳定性与空间结构关联性研究

【目的】研究林分空间结构与稳定性的关系是开展结构化森林经营的前提,旨在探索空间结构对林分稳定性的影响特征,为结构化森林经营提供支持与理论依据。【方法】以黄龙山油松人工林为研究对象,通过设置典型样地,采用最优林分的π值法则,选取10项稳定性指标进行稳定性评价,利用典型相关分析、逐步线性回归分析等方法研究空间结构(包括混交度M、角尺度W和Hegyi竞争指数CI)与林分稳定性ω的关联机制。【结果】1)林分稳定性ω平均值为0.18,变异系数为36%,总体评价结果偏差;混交度M平均值为0.26,变异系数为79%,研究区油松林分物种入侵差异大。2)典型相关分析显示,空间结构指数(包括混交度M、角尺度W和Hegyi竞争指数CI)与稳定性评价指标体系在整体上存在很强的线性相关,典型相关系数可达0.95。3)Pearson相关性分析中,W、M和CI均与ω强烈相关,相关系数分别为-0.5、0.61和-0.73。W与林分健康状态呈极显著负相关,相关系数为-0.63;M与树种多样性呈极显著正相关,与林分长势呈极显著负相关,相关系数分别为0.86、-0.66;CI与林分健康、林分密度呈极显著负相关,相关系数分别为-0.60、-0.57。4)逐步回归分析显示,混交度和林木竞争是影响稳定性的主要因素;由标准化系数可看出,林木竞争(-0.58)对稳定性的影响比混交度(0.39)大。【结论】空间结构与林分稳定性在整体上显著相关;林分混交程度显著提高林分稳定性,但是会削弱优势林木长势;团状分布格局加大了林木竞争,不利于林分稳定性。在结构调控中应适当提高林分混交程度,对竞争强度进行调整时可以连带调整林分的团状分布格局,从而提高林分稳定性水平。     

Surgical resection of an orbital fat prolapse in a California sea lion (Zalophus californianus)

A 23-year-old captive female California sea lion (Zalophus californianus) developed an inferiotemporal subconjunctival swelling of the right eye. Surgical excision of the mass was performed and a diagnosis of orbital fat prolapse was confirmed histopathologically. There was no recurrence of orbital fat prolapse at 15 months post operatively. This is the first known case of orbital fat prolapse in the California sea lion.