Effect of Se and VE Supplement on Semen Quality,Antioxidant Enzyme Activities and Heat Shock Protein Expression of Goat in High Temperature Season

This experiment was conducted to study the effect of selenium and vitamin E supplement on semen quality, antioxidant enzyme activities and heat shock protein expression of goat in Hainan high temperature season.16 adult Hainan Black goat with good health and approximate weight were randomly divided into 4 groups, fed with basal diet(control group), basal diet+0.5 mg/kg Se(Se group), basal diet+100 mg/kg VE(VE group), and basal diet+0.5 mg/kg Se+100 mg/kg VE(Se+VE group), respectively.The experimental period was 93 d.Semen samples were collected in the last week of the experiment on two consecutive days.The semen quality, antioxidant enzyme activities and heat shock protein expression were analyzed.The results showed that compared with control group, the ejaculate volume was not significantly affected by Se or VE supplement(P>0.05).Sperm density and sperm motility were increased significantly by Se and VE supplement(P<0.05), and the abnormal rate was decreased extremely significantly(P<0.01).The goats fed with Se and VE also had higher activities of GSH-Px(P<0.01), SOD(P<0.05), CAT(P<0.05) and T-AOC(P<0.01), and lower MDA concentration in seminal plasma(P<0.05).The relative expression levels of HSP70 and HSP90 mRNA in supplement groups were decreased extremely significantly(P<0.01).However, there were some certain differences between the Se and VE supplement groups on semen quality and heat shock protein expression.In conclusion, the supplementation of Se and VE could help to improve goat semen quality by increasing the sperm density, sperm motility, the antioxidant enzyme activities, and decreasing the abnormal rate in hot season of Hainan.Finally, Se and VE supplement had good effects on relieving the environment heat stress.     

Cyclooxygenase (COX) inhibitors and the intestine

Nonsteroidal anti-inflammatory drugs (NSAIDs) have long been used for the treatment of pain and inflammation because of their inhibitory effects on cyclooxygenase (COX). For almost as long as NSAIDs have been in use, multiple adverse effects have been noted. Assessment of many of these adverse effects have been complicated because of the discovery of multiple splice variants of the cox gene, and a greater array of COX inhibitors, especially the COX-2 selective inhibitors have become available. Some of these adverse effects cannot be readily explained by the effect of these drugs on COX. This has sparked a new field of investigation into the COX-independent effects of the COX inhibitors. The major noncyclooxygenase targets of the COX inhibitors of particular relevance to inflammation and the gastrointestinal tract are phosphatidylinositol 3'-kinase Akt signaling, uncoupling of oxidative phosphorylation, PPARgamma, nuclear factor KB, mitogen activated protein kinases, and heat shock proteins.     

NUMERICAL SOLUTIONS OF SHOCK WAVE FOCUSING WITH CCW METHOD

By the use of a numerical scheme of chisnell-Chester-Whitham Method (CCW), some numerical solutions to the problems of shock wave focusing are completed successfully and simply.     

Application of Engineering WorkStation in Analysis of Truck Crashworthiness

This paper presents the basic equations and algorithm of vehicle crashworthinessbriefly.Take a light-truck for example,some applied problems in ustng Engineering WorkStationto analysis truck crashworthiness are discussed.A installation method of contact surface is intro-duced,Finally,a nurnerical simulation result is presented.     

板料激光斜冲击下受力变形数学分析

金属板材的激光冲击成形通常采用激光束垂直作用于工件表面,产生垂直于表面的冲击波作用力使板料变形,但在曲面零件成形时很难满足法向垂直冲击,因此有必要对斜冲击下板料力学变形特性进行研究。本文研究了激光斜冲击受力变形模型,对板料深度方向(z轴)变形公式、板料短轴(y轴)在水平方向上变形公式进行了理论推导计算,通过把两变形合成,得到短轴(y轴)在空间内总变形公式,最后把实验测量结果与理论计算结果进行了比较,得出两者相符的结论。