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21.
Bovine spongiform encephalopathy: aspects of the clinical picture and analyses of possible changes 1986-1990. 总被引:1,自引:0,他引:1
A standard questionnaire was used to record the presence of specific clinical signs reported for histopathologically confirmed cases of bovine spongiform encephalopathy observed before June 30, 1990, and the frequencies of these signs were analysed. The signs most frequently recorded were apprehension, hyperaesthesia and ataxia, and there were variations in the frequency with which some signs were recorded in animals observed at different times during the epidemic. These variations were considered to be the result of differences between observers and differences in the duration of the illness, rather than a change in the clinical picture, which could possibly have occurred with a change in the nature of the agent to which the cattle had been exposed, or to a change in their response to the agent. 相似文献
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Information was obtained on the structure of the herds and flocks of a sample of 41 households on the three Maasai Group Ranches in Kenya. The purpose of the survey was to contribute to an intensive study of the livestock production system, and also to assess the amount of information that could be obtained from a herd structure study on its own. Differences in herd structure were related to the livestock wealth of the household, the stage of development of the Group Ranch as well as to the variation in climate, and production alternatives.Data from more than 5100 cattle revealed that Maasai herds contained less steers in 1982 (18%) than in 1968 (22%). The proportion of mature steers had also dropped from 5% (1968) to 2% (1982), with maximum valves of 3·2% on the most developed ranch and 2% for the wealthiest stratum of households. A high percentage of females had been retained (56%) giving a herd structure characteristic of subsistence production with milk as a primary output. This structure also caters for a strong market in immature animals and gives the herd a high potential for recovery after a drought. There appeared to be a trend towards increased use of introduced bulls, notably Sahiwal on the Small East African Zebu, with increased Group Ranch Development. However, this trend was confounded by a decreasing aridity gradient with increased development.On two of the ranches for which 1968 counts were available, cattle numbers were 119% of their previous value whereas small stock were 470%. The reason appears to be that increased sedentarisation without adequate range management has resulted in a severe reduction in grasses, and their replacement by forbs. These plants are more palatable to small stock which are better able to exploit the degraded habitat.Information from more than 2730 sheep and 2300 goats revealed that poor households preferred goats and richer households, sheep. The Small East African Goat was ubiquitous, but the most developed ranch had crossed Dorper onto Maasai sheep whereas the least developed and most arid ranch had introduced Somali Blackhead sheep. The Dorper crossbred catered for a market for mutton whereas the Blackhead was primarily for home consumption of fat.The conclusion is that Group Ranch Development has not projected the Maasai into commercial beef ranching as originally planned, but their production system has not stood still. A study of herd structures was a good way of demonstrating the evolution of the system. The method was simple but was dependent for its success on fairly involved and time-consuming sampling and data collection procedures. 相似文献
24.
The housing, management and internal parasite control practices used in piggeries in Western Australia was surveyed by interviewing the owner/manager of 100 randomly selected piggeries. At the time of the interview 20 faecal samples were collected from pigs and examined for evidence of internal parasites. Most herds (80%) in which anthelmintics were used, had evidence of nematode infection. Some pig producers were using an anthelmintic that was ineffective against nematode species present while some herds had nematodes that should have been controlled by the anthelmintic being used. Prevalence of nematode infection was higher in pigs run in paddocks than in pigs housed intensively. Washing sows prior to farrowing was associated with a lower prevalence of nematode infection. The findings suggested that pig producers should ensure that the anthelmintic used is effective against the nematodes present in their pigs. It was concluded that administering anthelmintics as a single dose in the feed may not be the most effective method of deworming pigs. 相似文献
25.
Sayers G Sweeney T 《Animal health research reviews / Conference of Research Workers in Animal Diseases》2005,6(2):159-171
Efforts to curb production losses caused by nematode parasitism in sheep have led to the development of a number of control methods to complement or replace anthelmintics. The need for alternative control measures stems from the emergence of anthelmintic-resistant parasitic nematodes with reports of multi-class resistance to these drugs now emerging. A number of these control methods such as predacious microfungi, protein supplementation, plant extracts in feed and vaccines have demonstrated potential to control infection but require development and examination under natural conditions. Breeding for natural resistance to nematode infection has already shown success in controlling the disease under natural conditions. Selection for resistance is currently based on fecal egg count measurements but identification of genetic indicators of resistance will provide a more efficient method of selection. Current quantitative trait loci for nematode resistance include the MHC genes, interferon gamma gene, IgE gene and microsatellites on chromosome 1, 5 and 6. This paper reviews the current alternatives to anthelmintics to control infection, with an emphasis on breeding for host resistance and identification of genetic indicators of resistance. 相似文献
26.
del Rio Vilas VJ Sayers R Sivam K Pfeiffer D Guitian J Wilesmith JW 《Preventive veterinary medicine》2005,67(4):303-317
We applied capture–recapture methodology (CRC) to data from three surveillance sources (statutory notification, abattoir survey (AS) and fallen stock (FS) survey) to estimate the number of holdings infected with scrapie in Great Britain and to assess the sensitivity of the surveillance network. Between January 1, 2002 and March 31, 2003, 144 holdings were identified by the three sources. Using CRC modelling techniques, we estimated a minimum lower bound for the total number of holdings infected as 642. A biologically plausible positive dependence between the statutory reporting and the fallen stock survey was found statistically significant. The sensitivity of the three sources combined was very low. The integration of the three overlapping sources provided a better understanding of the interactions within the surveillance network. However, the scarcity of the data and reduced overlapping among sources only allowed for very cautious inferences to be drawn about the true proportion of scrapie affected holdings in the national population. Future surveys and surveillance activities should be planned such that the resulting data can be used more effectively as part of CRC modelling approaches. 相似文献
27.
Phylogenetic characterisation of bluetongue viruses from naturally-infected insects, cattle and sheep in Australia 总被引:1,自引:0,他引:1
KA McCOLL AR GOULD LI PRITCHARD L MEL VILLE† G. BELLIS† 《Australian veterinary journal》1994,71(4):102-105
SUMMARY The polymerase chain reaction was used to detect the presence of blue-tongue virus (BTV) in a number of clinical and insect samples collected in the Northern Territory of Australia. Sequence analyses of the amplified BTV genes differentiated endemic Australian and exotic viruses. Two potential exotic BTV were detected as a result of PCR analyses of blood from sentinel animals and of the insect vector, Culicoides wadai. The detection of BTV in C wadai was the first direct demonstration of the presence of BTV in this potential vector. This new technology can significantly reduce the time taken for a diagnosis from a clinical sample and increase the amount of useful information obtained on a BTV isolate by using rapid sequencing techniques. Sequence data were used to differentiate between BTV20 isolated in 1975 and two isolates of the same serotype, isolated in 1992, and indicated that the latter were probably a recent incursion into Australia from Indonesia due to their greater VP3 sequence homology to the BTV9 (Java) than to Australian BTV isolates. 相似文献
28.
The lipopolysaccharide of Salmonella and other Gram negative pathogenic species has been implicated as a major virulence determinant and in this study we report the role of LPS of S. Enteritidis in the colonisation and persistent gastrointestinal infection of young poultry. The gene encoding the unique O-antigen ligase, waaL, was mutated by insertional inactivation in a well characterised S. Enteritidis strain, S1400/94. The waaL mutant, designated PCP, produced rough colonies on agar medium, did not agglutinate O9 antiserum, did not produce an LPS ladder on silver stained gels and was serum sensitive. PCP and a nalidixic acid marked derivative of S1400/94 (S1400/94 Nalr) were used to orally challenge young chicks, separately and together in competitive index experiments. At post-mortem examination of 1-day-old chicks challenged S1400/94 Nalr and PCP separately there were no significant differences in the numbers of S1400/94 Nalr and PCP bacteria in tissues sampled on days 1, 2, and 5. By day 42 after challenge S1400/94 Nalr bacteria were recovered in significantly higher numbers than PCP from the caecal contents (P < 0.001). In competitive index studies in the 1-day-old chick PCP colonised, invaded and persisted in lower numbers than S1400/94 Nalr. In 4-week-old chicks challenged separately, PCP bacteria were recovered from all tissues examined in significantly lower numbers than S1400/94 Nalr. In competitive index experiments in 4-week-old chicks, PCP was not detected at any site and at any time point. Therefore, the O-antigen of S. Enteritidis plays an important role in poultry infections although this role is less important in the newly hatched chick. 相似文献
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AIMS: To evaluate the effectiveness of treatment programmes that included controlled internal drug-releasing (CIDR) devices containing progesterone (P4) in improving synchrony of oe- strus, and conception and pregnancy rates in cycling, anoestrous and inseminated dairy cows, using meta-analysis. To describe the difference in response between cycling and anoestrous cows to CIDR-based synchrony programmes. METHODS: Scientific papers written in the English language between 1989 and 2002 that investigated the effects of treat- ment programmes including CIDR devices on reproductive per- formance in dairy heifers or lactating dairy cows were identified using a computerised literature search. The criteria for inclusion incorporated evidence that treatment allocation was completely randomised; the population studied was lactating dairy cows; and that data were available on submission, conception and pregnancy rates and their associated measures of variability. Re- productive outcomes from 25 synchrony trials (total n= 11,058 cows) were analysed. Summary measures of the effect of treat- ment on reproductive outcome were assessed using fixed- and random-effects Bayesian meta-analysis models. RESULTS: Treatment programmes including a CIDR device increased the risk of submission in cycling cows (predicted Bayesian RR=2.86, 95% credible interval 1.46–5.67). Compared with controls, synchrony programmes including CIDR devices in cycling dairy cows had no effect on the risk of conception to first service post-treatment (predicted Bayesian RR=1.00, 95% credible interval=0.80-1.24). Compared with controls, synchrony programmes including CIDR devices had no effect on the risk of pregnancy throughout the mating period (pre- dicted Bayesian RR=1.02, 95% credible interval=0.89-1.17). In anoestrous cows, CIDR treatment had no effect on the risk of conception to first service post-treatment and no effect on the risk of pregnancy throughout the mating period, compared with anoestrous, untreated controls (predicted Bayesian RR=0.91 and 0.97, respectively; 95% credible interval=0.68–1.26 and 0.59-1.60, respectively). CONCLUSION: The results of this meta-analysis showed that synchrony programmes using CIDR devices combined with other hormones reliably enhanced submission rates in lactat- ing dairy cows. The relatively small number of trials with data suitable for analysis and the heterogeneity of results at the indi- vidual trial level limited our ability to confirm either a beneficial or deleterious effect of treatment on conception or pregnancy rates. Further randomised, controlled trials to evaluate the ef- fectiveness of this form of reproductive therapy in commercial dairy farms are needed. 相似文献