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401.
Eva B. Thorstad Doug Bliss Cindy Breau Kim Damon-Randall Line E. Sundt-Hansen Emma M.C. Hatfield Grant Horsburgh Heidi Hansen Niall Ó. Maoiléidigh Timothy Sheehan Stephen G. Sutton 《水产资源保护:海洋与淡水生态系统》2021,31(9):2654-2665
- Atlantic salmon populations have declined in recent decades. Many of the threats to the species during its freshwater and coastal residency periods are known, and management approaches are available to mitigate them. The global scale of climate change and altered ocean ecosystems make these threats more difficult to address.
- Managers need to be aware that promoting strong, healthy, and resilient wild populations migrating from rivers is the optimal approach currently to reduce the impacts of changing ecosystems and low marine survival. We argue that a fundamental strategy should be to ensure that the highest number of wild smolts in the best condition leave from rivers and coastal areas to the ocean. There is great scope for water quality, river regulation, migration barriers, and physical river habitat improvements.
- Maintenance of genetic integrity and diversity of wild populations by eliminating interbreeding with escaped farmed salmon, eliminating poorly planned stocking, and reducing impacts that reduce population sizes to dangerously low levels will support the ability of Atlantic salmon to adapt to changing environments. Reducing the impacts from aquaculture and other human activities in coastal areas can greatly increase marine survival in affected areas.
- As most of the threats to wild salmon are the result of human activities, a focus on human dimensions and improved communication, from scientific and management perspectives, needs to be increasingly emphasized. When political and social will are coupled with adequate resources, managers often have the tools to mitigate many of the threats to wild salmon.
402.
Kerstin?Hund-RinkeEmail author Werner?Koerdel Dieter?Hennecke Rudolf?Achazi Dietmar?Warnecke Berndt-Michael?Wilke Birgit?Winkel Stefanie?Heiden 《Journal of Soils and Sediments》2002,2(2):83-90
For the assessment of contaminated or remediated soils, aside from chemical analyses, ecotoxicological tests are performed which focus on the retention function of soils (determined by tests with aqueous soil extracts) and on the habitat function (determined by tests with soil). Whereas numerous tests exist as standardized guidelines for identifying the effect of chemicals, this is not the case for the assessment of soil quality. A round-robin test was performed to monitor the comparability of the results from ecotoxicological test methods on soils and to facilitate the standardization of corresponding test methods. Four contaminated soils were tested using a total number of fifteen test systems, including ecotoxicological and genotoxicological tests with soil extracts and soil. In the second part of this publication series, the results obtained from the tests with soil microorganisms and soil fauna are presented. 相似文献
403.
404.
Hiep T. Dao Nishchal K. Sharma Emma J. Bradbury Robert A. Swick 《Journal of animal physiology and animal nutrition》2021,105(4):731-746
Arginine activity in broiler diets can be supplied by L-arginine (Arg), guanidinoacetic acid (GAA) and L-citrulline (Cit), all of which are commercially available. This study was conducted to assess the effects of Arg source and level on broiler performance, nutrient digestibility and carcass parameters. Day-old Ross 308 cockerels (n = 768) were assigned to one of eight dietary treatments using a completely randomized design: normal protein (NP), low protein deficient in Arg (LP) and LP with two levels of either Arg (0.238% and 0.476%), GAA (0.309% and 0.618%) or Cit (0.238 and 0.476%). The LP was 5 percentage points lower in protein level than the NP. Wheat, sorghum, soya bean meal, canola meal, and meat and bone meal-based diets were fed over three feeding phases to 6 replicate floor pens with 16 birds each. Compared to NP, birds fed LP had reduced feed intake (FI, p < 0.001), reduced body weight gain (BWG, p < 0.001) and increased feed conversion ratio (FCR, p < 0.001) from day 0 to day 35. Additions of Arg or Cit to the LP at both levels resulted in increased BWG and reduced FCR (p < 0.05). Birds fed LP with GAA added had lower FCR (p < 0.05) but not higher BWG (p > 0.05) compared with the LP observed from day 0 to day 35. Supplementation of Arg, Cit and the low level of GAA to LP resulted in increased carcass yield, bone length, diameter and ash (p < 0.05) but did not increase ileal energy or nitrogen digestibility (p > 0.05). The findings indicate that Cit is an efficacious source of Arg activity in Arg-deficient diets. 相似文献
405.
Andries K Verhasselt P Guillemont J Göhlmann HW Neefs JM Winkler H Van Gestel J Timmerman P Zhu M Lee E Williams P de Chaffoy D Huitric E Hoffner S Cambau E Truffot-Pernot C Lounis N Jarlier V 《Science (New York, N.Y.)》2005,307(5707):223-227
The incidence of tuberculosis has been increasing substantially on a worldwide basis over the past decade, but no tuberculosis-specific drugs have been discovered in 40 years. We identified a diarylquinoline, R207910, that potently inhibits both drug-sensitive and drug-resistant Mycobacterium tuberculosis in vitro (minimum inhibitory concentration 0.06 mug/ml). In mice, R207910 exceeded the bactericidal activities of isoniazid and rifampin by at least 1 log unit. Substitution of drugs included in the World Health Organization's first-line tuberculosis treatment regimen (rifampin, isoniazid, and pyrazinamide) with R207910 accelerated bactericidal activity, leading to complete culture conversion after 2 months of treatment in some combinations. A single dose of R207910 inhibited mycobacterial growth for 1 week. Plasma levels associated with efficacy in mice were well tolerated in healthy human volunteers. Mutants selected in vitro suggest that the drug targets the proton pump of adenosine triphosphate (ATP) synthase. 相似文献
406.
Schawinski K Justham S Wolf C Podsiadlowski P Sullivan M Steenbrugge KC Bell T Röser HJ Walker ES Astier P Balam D Balland C Carlberg R Conley A Fouchez D Guy J Hardin D Hook I Howell DA Pain R Perrett K Pritchet C Regnault N Yi SK 《Science (New York, N.Y.)》2008,321(5886):223-226
Massive stars undergo a violent death when the supply of nuclear fuel in their cores is exhausted, resulting in a catastrophic "core-collapse" supernova. Such events are usually only detected at least a few days after the star has exploded. Observations of the supernova SNLS-04D2dc with the Galaxy Evolution Explorer space telescope reveal a radiative precursor from the supernova shock before the shock reached the surface of the star and show the initial expansion of the star at the beginning of the explosion. Theoretical models of the ultraviolet light curve confirm that the progenitor was a red supergiant, as expected for this type of supernova. These observations provide a way to probe the physics of core-collapse supernovae and the internal structures of their progenitor stars. 相似文献
407.
Okkenhaug K Bilancio A Farjot G Priddle H Sancho S Peskett E Pearce W Meek SE Salpekar A Waterfield MD Smith AJ Vanhaesebroeck B 《Science (New York, N.Y.)》2002,297(5583):1031-1034
Class IA phosphoinositide 3-kinases (PI3Ks) are a family of p85/p110 heterodimeric lipid kinases that generate second messenger signals downstream of tyrosine kinases, thereby controlling cell metabolism, growth, proliferation, differentiation, motility, and survival. Mammals express three class IA catalytic subunits: p110alpha, p110beta, and p110delta. It is unclear to what extent these p110 isoforms have overlapping or distinct biological roles. Mice expressing a catalytically inactive form of p110delta (p110delta(D910A)) were generated by gene targeting. Antigen receptor signaling in B and T cells was impaired and immune responses in vivo were attenuated in p110delta mutant mice. They also developed inflammatory bowel disease. These results reveal a selective role for p110delta in immunity. 相似文献
408.
Protein requirements of preschool children consuming rice-milk,rice-toasted mung bean,and rice diets
Maria A. Isabel Cabrera-Santiago Carmen LL. Intengan Benigan V. Roxas Bienvenido O. Juliano Consuelo M. Perez Anacleta S. Loyola Emma R. Alejandro Jovina N. Abadilla Gracia FE B. Yu Aida C. Mallillin 《Plant foods for human nutrition (Dordrecht, Netherlands)》1986,36(3):167-178
Rice-milk and rice-toasted mung bean diets, and a high-protein rice (IR58 milled rice) were evaluated as part of a study on the protein requirements of toddlers consuming rice-based diets following the multilevel N balance method. Milk or mung bean contributed 1/3 of dietary N. At a daily energy intake of 418 kJ/kg body weight, weight losses were observed for all diets. The safe level of protein intakes obtained allowing 10 mg N/kg body weight/day for miscellaneous integumental losses and 15 mg N/kg body weight/day for growth was 1.11 g/kg body weight/day for the rice-milk diet and 1.34 g for the rice-mung bean diet. Preliminary data on four children indicate a safe level of protein intake of 1.44 g/kg/day for the IR58 milled rice. The protein quality of the high-protein rice as determined by the very short term N balance index on three children was 79–80% relative to milk. 相似文献
409.
Candeias V Nymoen LL Patterson E Scholtens S 《Public health nutrition》2008,11(6):652; author reply 652
410.
Foster E Matthews JN Nelson M Harris JM Mathers JC Adamson AJ 《Public health nutrition》2006,9(4):509-514
BACKGROUND: In order to obtain a measure of nutrient intake, a measure or estimate of the amount of food consumed is required. Weighing foods imposes a large burden on subjects, often resulting in underreporting. Tools are available to assist subjects in providing an estimate of portion size and these include food photographs. The application of these tools in improving portion size estimation by children has not been investigated systematically. OBJECTIVES: To assess the accuracy with which children are able to estimate food portion sizes using food photographs designed for use with adults, and to determine whether the accuracy of estimates is improved when age-appropriate portion size photographs are provided. DESIGN: Original data from three separate studies, on the accuracy of portion size estimates by adults using food photographs, by children using adult photographs and by children using age-appropriate photographs, are analysed and compared. SUBJECTS: One hundred and thirty-five adults aged 18 to 90 years and 210 children aged 4 to 11 years. RESULTS: Children's estimates of portion sizes using age-appropriate food photographs were significantly more accurate (an underestimate of 1% on average) than estimates using photographs designed for use with adults (an overestimate of 45% on average). Accuracy of children's estimates of portion size using age-appropriate photographs was not significantly different from that of adults. Children overestimated a food's weight by 18% on average and adults underestimated by 5%. CONCLUSIONS: Providing children with food photographs depicting age-appropriate portion sizes greatly increases the accuracy of portion size estimates compared with estimates using photographs designed for use with adults. 相似文献