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11.
The development of a method for assaying S-3-(hexan-1-ol)-L-cysteine, the cysteinylated precursor of 3-mercaptohexan-1-ol (P-3MH), in must has made it possible to study its impact on the aromatic potential of Merlot and Cabernet Sauvignon grape varieties used to produce rose wines in Bordeaux. The original feature of this method is the purification of very small volumes of must (500 microL) containing P-3MH by affinity chromatography and gas-phase chromatography coupled with mass spectrometry of the purified precursor in trimethylsilylated derivative form. Assays of the cysteinylated precursor in Merlot and Cabernet Sauvignon grapes showed that it was mainly located in the grape skins (60%). Prolonged juice-skin contact increased the must's P-3MH content, and this phenomenon was more marked at higher temperatures. Assessment of the aromatic potential of must used to produce rose wines by chemical analysis of an S-cysteine conjugate is mentioned for the first time. 相似文献
12.
Abelson JF Kwan KY O'Roak BJ Baek DY Stillman AA Morgan TM Mathews CA Pauls DL Rasin MR Gunel M Davis NR Ercan-Sencicek AG Guez DH Spertus JA Leckman JF Dure LS Kurlan R Singer HS Gilbert DL Farhi A Louvi A Lifton RP Sestan N State MW 《Science (New York, N.Y.)》2005,310(5746):317-320
Tourette's syndrome (TS) is a genetically influenced developmental neuropsychiatric disorder characterized by chronic vocal and motor tics. We studied Slit and Trk-like 1 (SLITRK1) as a candidate gene on chromosome 13q31.1 because of its proximity to a de novo chromosomal inversion in a child with TS. Among 174 unrelated probands, we identified a frameshift mutation and two independent occurrences of the identical variant in the binding site for microRNA hsa-miR-189. These variants were absent from 3600 control chromosomes. SLITRK1 mRNA and hsa-miR-189 showed an overlapping expression pattern in brain regions previously implicated in TS. Wild-type SLITRK1, but not the frameshift mutant, enhanced dendritic growth in primary neuronal cultures. Collectively, these findings support the association of rare SLITRK1 sequence variants with TS. 相似文献
13.
The study here was conducted on nearly 12,000 apricot seedlings in the Malatya Region in the Eastern part of Turkey. This
region is famous for its horticulture based mainly on apricot production and the Country's highest apricot production originates
from this region. The flower and fruit characteristics of all populations, which include apricot seedlings, in the region
were evaluated. Based on their horticultural performances, 13 genotypes were selected, of which seven were considered as apricots
served in dried form and six as in table consumption form. Among the selected genotypes, the fruit weight ranged between 28.5
and 71.19 g, soluble solids ranged between 12.7 and 26.5%, while the range in total acidity was between 0.35 and 1.80% and
fruit development period was between 87 and 183 days. To determine the selected genotypes performance in a similar environment,
they were grafted on to 4-year-old rootstocks. The results from these combinations showed that there was some decrease, especially
in fruit size and soluble solids, in the genotypes performance when compared to the results of the initial observations. Some
differences were also detected in taste, fruit shape, pit shape, fruit flesh firmness, skin and flesh colors. The dry fruit
yield was determined as 22.50–28.36% for the selected dry apricot genotypes. The dry fruit yield of all seven genotypes considered
for dry consumption were similar to ‘Hacıhaliloğlu’ and higher than ‘Canino’, which were evaluated as control cultivars. 相似文献
14.
Ground red peppers: capsaicinoids content,Scoville scores,and discrimination by an electronic nose 总被引:1,自引:0,他引:1
Korel F Bagdatlioglu N Balaban MO Hişil Y 《Journal of agricultural and food chemistry》2002,50(11):3257-3261
High-pressure liquid chromatography (HPLC) was used to determine the capsaicin, dihydrocapsaicin, and total capsaicinoids levels of different ground red pepper samples obtained from local retail markets in Izmir, Turkey. Scoville scores were determined using sensory tests. An electronic nose (EN) was used to discriminate ground red pepper samples by headspace volatiles. EN data were analyzed using discriminant function analysis (DFA). An overall correct classification rate of pepper varieties by EN of 91% was obtained. A linear correlation between capsaicin, dihydrocapsaicin, and total capsaicinoids and Scoville scores was also observed, and R (2) values of 0.89, 0.85, and 0.91 were obtained, respectively. 相似文献
15.
Ozlem Nisbet H Ozak A Yardimci C Nisbet C Yarim M Bayrak IK Sirin YS 《Research in veterinary science》2012,93(1):488-493
The aim of this study was to investigate bee venom and hyaluronic acid in the intra-articular treatment of osteoarthritis in an experimental rabbit model. Forty-five rabbits were used and they were randomly divided into three groups (BVI, BVII, and HA) and each group was divided to two subgroups to evaluate the radiologic, magnetic resonance imaging, histopathologic, and biochemical evaluation in post treatment second week (a) and twelfth week (b). Radiologically, a significant difference was observed in the HA group (P<0.05). The MRI evaluation of at any time in group BVI(b) was found to be different. No significant differences were seen between the groups, biochemically. Histopathologically, cellularity, and orthochromasia was evident with Safranin-O in the BVI(b) and BVII(a); adhesions were seen in the BVII(a) group and clustering of chondrocyte in the HA(b) group were found to be different. Consequently, intra-articular application of HA and BV for experimental model of osteoarthritis has no significant influence upon recovery after therapy. 相似文献
16.
17.
Tolga Guvenc Mustafa Yavuz Gulbahar Murat Yarim Yonca Betil Kabak Onder Karayigit Mahmut Sozmen 《Journal of veterinary science (Suw?n-si, Korea)》2012,13(1):39-42
The aim of this study was to evaluate prognostic and/or diagnostic factors of canine mammary tumors by immunohistochemically analyzing the expression of alpha basic crystallin (αB-c). For this, formalin-fixed, paraffin-embedded blocks of 51 naturally-occurring canine mammary tumors (11 benign and 40 malignant) were used. Tissue from eight normal canine mammary glands were served as a control. Immunohistochemically, in the control mammary tissues, a few luminal epithelial cells were αB-c positive but myoepithelial cells were negative. In benign or simple type malignant tumors, αB-c expression was observed in luminal epithelial cells while the myoepithelial basal cells were negative. In benign or complex type malign tumors, positive staining was predominantly found in the cytoplasm of epithelial cells. Immunoreactivity of αB-c was also observed in neoplastic myoepithelial cells. Statistically, the number of cells immunolabeled with αB-c was found to be significantly different among tissues from normal canine mammary glands, benign lesions, and malignant tumors (p < 0.05). αB-c immunoreactivity was higher in malignant tumors than the control mammary tissues (p < 0.001). Data obtained in the current study revealed a strong association between high expression levels of αB-c and primary mammary gland tumors in canines. 相似文献
18.
İsmail Hamad Özlem Erol-Dayi Murat Pekmez Evren Önay-Uçar Nazlı Arda 《Plant foods for human nutrition (Dordrecht, Netherlands)》2010,65(1):44-49
The objectives of this study were to examine the free radical scavenging activity and the protective effects against macromolecular
oxidation as well as the cytotoxic activity of Aphanes arvensis aqueous and methanolic extracts. Free radical scavenging activity was determined by DPPH method. The methanolic extract showed
a scavenging activity nearly equivalent to Trolox and Vitamin C and has an IC50 value of 4.54 μg/mL. Total antioxidant capacity was determined by CUPRAC method. The antioxidant capacity of aqueous and
methanolic extract was 0.792 and 1.550 mmol TE/g DWE, respectively. The protective effect of A. arvensis extracts against lipid peroxidation was evaluated using a liposome oxidation system. The methanolic extract was more active
than the aqueous extract. The aqueous extract possessed protective effect against protein oxidation in a dose dependent manner.
Both extracts showed inhibitory effect on DNA oxidation as measured by plasmid relaxation assay. Results presented here indicate
that A. arvensis possess strong antioxidant activity and protective effects with very little cytotoxic effect, and they can therefore be used
as a natural additive in food, cosmetic and pharmaceutical industries. 相似文献
19.
Mustafa Yipel Cemil Kürekci İbrahim O Tekeli Murat Metli Fatih Sakin 《Aquaculture Research》2017,48(7):3829-3836
The aim of the study was to monitor the occurrence of 37 antibiotics from different classes including fluoroquinolone, tetracycline, macrolide, sulphonamide, penicillin, amphenicol and cephalosporin in three different farmed fish species (n = 75; rainbow trout, see bass, gilthead see bream) from five cities in Turkey. A method for LC‐MS/MS was optimized and validated to assess these antibiotics. As a result, 25 samples showed contamination with at least one antibiotic residue. The most detected antibiotics were norfloxacin (NOR) (18.7%), marbofloxacin (MAR) (12%), tetracycline (TC) (10.7), danofloxacin (DAN) (9.3%), oxytetracycline (OTC) (9.3%), tilmicosin (TLM) (8%) and enrofloxacin (ENR) (6.7%). A total of 17.3% of samples examined were found to be contaminated with residues exceeding the maximum residue limits (MRLs). The results indicate that antibiotics are frequently used in aquaculture production without the lack of knowledge. This study also revealed that the consumption of farmed fish could produce a public health concern as the level of residues for some antibiotics was much higher than MRLs. 相似文献
20.
Sebahattin Ergün Murat Soyutürk Betül Güroy Derya Güroy Daniel Merrifield 《Aquaculture International》2009,17(4):355-361
A nutrition trial was conducted to investigate the effects of dietary lipid levels and supplemental Ulva meal on growth performance,
feed efficiency, nutrient utilization, and body composition of juvenile Nile tilapia, Oreochromis niloticus. Four isonitrogenous (CP 40%) diets containing 0% and 5% Ulva meal were formulated to contain 10% (low-lipid; LL) and 20%
(high-lipid; HL) crude lipid. Triplicate groups of fish (~10 g) were fed to apparent satiation three times daily for 16 weeks.
Fish fed 5% Ulva meal showed an increased growth performance (P < 0.05) compared with fish fed non-Ulva supplemented diets, irrespective of dietary lipid level. In particular, the incorporation
of Ulva meal improved specific growth rate (SGR), feed conversion ratio (FCR), and protein efficiency ratio (PER). Feeding
fish 5% Ulva meal diets resulted in significantly lower carcass lipid content. The results indicate that 5% inclusion of Ulva
meal at both dietary lipid levels improves growth performance, feed efficiency, nutrient utilization, and body composition
of Nile tilapia. 相似文献