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61.
Saito M Saito K Kunisaki N Kimura S 《Journal of agricultural and food chemistry》2002,50(24):7169-7174
We have investigated the inhibitory effects of polyphenols from natural products, such as green tea, bilberry, grape, ginkgo, and apple, on rainbow trout gelatinase activities. Gelatinases from the skin, muscle, and blood of rainbow trout contained serine proteinase, metalloproteinase, and other proteinase activities as measured by gelatin zymography. The polyphenols of green tea caused the strong inhibition of some gelatinase activities when compared with those of the other products. This inhibition was quite similar to that of metalloproteinase by ethylenediaminetetraacetic acid, suggesting that the effects of green tea polyphenols on proteinase activities are specific for metalloproteinases. The major catechins of green tea polyphenols were then separated and identified by reverse-phase chromatography to be (-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin, (-)-epicatechin gallate, and (-)-epicatechin. The effects of these catechins on gelatinase activities were examined; the most potent inhibitor of metalloproteinase activities was found to be EGCG. These results have indicated that green tea polyphenols including EGCG are useful for regulating metalloproteinase activities of fish meat. 相似文献
62.
Coral reefs are considered to be a source of atmospheric carbon dioxide because of their high calcium carbonate production and low net primary production. This was tested by direct measurement of diurnal changes in the partial pressure of carbon dioxide (Pco(co2)) in reef waters during two 3-day periods, one in March 1993 and one in March 1994, on Shiraho reef of the Ryukyu Islands, Japan. Although the Pco(co2) values in reef waters exhibited large diurnal changes ranging from 160 to 520 microatmospheres, they indicate that the reef flat area is a net sink for atmospheric carbon dioxide. This suggests that the net organic production rate of the reef community exceeded its calcium carbonate production rate during the observation periods. 相似文献
63.
64.
Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene 总被引:11,自引:0,他引:11
D M Kranz H Saito C M Disteche K Swisshelm D Pravtcheva F H Ruddle H N Eisen S Tonegawa 《Science (New York, N.Y.)》1985,227(4689):941-945
Two independent methods were used to identify the mouse chromosomes on which are located two families of immunoglobulin (Ig)-like genes that are rearranged and expressed in T lymphocytes. The genes coding for the alpha subunit of T-cell receptors are on chromosome 14 and the gamma genes, whose function is yet to be determined, are on chromosome 13. Since genes for the T-cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig-like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B-cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains. The findings do not support earlier contentions that genes for T-cell receptors are linked to the Ig heavy chain locus (mouse chromosome 12) or to the major histocompatibility complex (mouse chromosome 17). 相似文献
65.
More than 50 cores ranging in age from Pliocene to Lower Miocene have been recovered from the East Pacific Rise. Near the crestal regions the sediment cover is thin or lacking, and only Pleistocene sediments were recovered. On the flanks, the sediment thickness increases and pre-Pleistocene sediments are encountered. This pattern of increasing age and increasing sediment thickness away from the axis of the rise is in agreement with that predicted for spreading of the ocean floor. 相似文献
66.
Hiroaki Kawamura 《Agriculture and Human Values》2004,21(2-3):157-169
Indigenous ecologies in industrial societies need immediate attention in light of the ongoing debate on indigenous resource rights and decreasing biodiversity. This paper examines the functions and meanings of hunting, fishing, and gathering activities among contemporary Nez Perce Indians in Idaho, USA. The collected data were analyzed with Pierre Bourdieu's (1977) concepts of “symbolic capital” and “practice” within the framework of political ecology. The results clearly demonstrate that hunting, fishing, and gathering practices play significant roles not only in social and religious but also economic and political senses within the contemporary Nez Perce society. This study suggests that investigation of indigenous ecologies in industrial societies take a synthesized approach between idealist and materialist perspectives. 相似文献
67.
Gaudi BS Bennett DP Udalski A Gould A Christie GW Maoz D Dong S McCormick J Szymanski MK Tristram PJ Nikolaev S Paczynski B Kubiak M Pietrzynski G Soszynski I Szewczyk O Ulaczyk K Wyrzykowski L;OGLE Collaboration Depoy DL Han C Kaspi S Lee CU Mallia F Natusch T Pogge RW Park BG;MuFUN Collaboration Abe F Bond IA Botzler CS Fukui A Hearnshaw JB Itow Y Kamiya K Korpela AV Kilmartin PM Lin W Masuda K Matsubara Y Motomura M Muraki Y Nakamura S Okumura T Ohnishi K Rattenbury NJ Sako T Saito T Sato S 《Science (New York, N.Y.)》2008,319(5865):927-930
Searches for extrasolar planets have uncovered an astonishing diversity of planetary systems, yet the frequency of solar system analogs remains unknown. The gravitational microlensing planet search method is potentially sensitive to multiple-planet systems containing analogs of all the solar system planets except Mercury. We report the detection of a multiple-planet system with microlensing. We identify two planets with masses of approximately 0.71 and approximately 0.27 times the mass of Jupiter and orbital separations of approximately 2.3 and approximately 4.6 astronomical units orbiting a primary star of mass approximately 0.50 solar mass at a distance of approximately 1.5 kiloparsecs. This system resembles a scaled version of our solar system in that the mass ratio, separation ratio, and equilibrium temperatures of the planets are similar to those of Jupiter and Saturn. These planets could not have been detected with other techniques; their discovery from only six confirmed microlensing planet detections suggests that solar system analogs may be common. 相似文献
68.
Hu J Zhong C Ding C Chi Q Walz A Mombaerts P Matsunami H Luo M 《Science (New York, N.Y.)》2007,317(5840):953-957
Carbon dioxide (CO2) is an important environmental cue for many organisms but is odorless to humans. It remains unclear whether the mammalian olfactory system can detect CO2 at concentrations around the average atmospheric level (0.038%). We demonstrated the expression of carbonic anhydrase type II (CAII), an enzyme that catabolizes CO2, in a subset of mouse olfactory neurons that express guanylyl cyclase D (GC-D+ neurons) and project axons to necklace glomeruli in the olfactory bulb. Exposure to CO2 activated these GC-D+ neurons, and exposure of a mouse to CO2 activated bulbar neurons associated with necklace glomeruli. Behavioral tests revealed CO2 detection thresholds of approximately 0.066%, and this sensitive CO2 detection required CAII activity. We conclude that mice detect CO2 at near-atmospheric concentrations through the olfactory subsystem of GC-D+ neurons. 相似文献
69.
Kumagai H Miyakawa K Negishi H Inoue H Obara K Suetsugu D 《Science (New York, N.Y.)》2003,299(5615):2058-2061
Very-long-period (VLP) signals showing simple decaying harmonic oscillations with periods near 10 seconds and lasting for about 300 seconds were observed in association with an earthquake swarm that occurred beneath Hachijo Island, Japan. Results from the source-mechanism analysis and waveform simulation based on a fluid-filled crack model consistently point to the resonance of a dike filled with a basaltic magma as the source of the VLP signals. Thus, VLP signals can be used to probe the state of the fluid and dynamic processes within a volcanic system. 相似文献
70.
Matsubara H Yoshimoto S Saito H Jianglin Y Tanaka Y Noda S 《Science (New York, N.Y.)》2008,319(5862):445-447
Shorter-wavelength surface-emitting laser sources are important for a variety of fields, including photonics, information processing, and biology. We report on the creation of a current-driven blue-violet photonic-crystal surface-emitting laser. We have developed a fabrication method, named "air holes retained over growth," in order to construct a two-dimensional gallium nitride (GaN)/air photonic-crystal structure. The resulting periodic structure has a photonic-crystal band-edge effect sufficient for the successful operation of a current-injection surface-emitting laser. This represents an important step in the development of laser sources that could be focused to a size much less than the wavelength and be integrated two-dimensionally at such short wavelengths. 相似文献