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81.
Defective phagocytosis of isolated rod outer segments by RCS rat retinal pigment epithelium in culture 总被引:5,自引:0,他引:5
Retinal pigment epithelium cultured from normal rats phagocytizes large amounts of rod outer segment fragments isolated from normal rats and from RCS rats with inherited retinal degeneration. Cultured RCS rat pigment epithelium rarely ingests outer segment material, although the cells extend cellular processes around fragments of either type. Both normal and RCS pigment epithelium phagocytize polystyrene spheres. This demonstrates that RCS rat pigment epithelial cells contain a defect in the mechanism for phagocytizing outer segments. 相似文献
82.
L V Knutson C O Berg L J Edwards A D Bratt B A Foote 《Science (New York, N.Y.)》1967,156(774):522-523
Larvae of 13 species of Pherbellia and Colobaea that feed in exposed aquatic snails uitilize a product of the Malpighian tubules before they pupate to form a plate-like structure within the shell or to reinforce the anterior end of the puparium. The substance is partly calcium carbonate, and carbonic anhydrase may be involved in its production. 相似文献
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Use of variations in natural nitrogen isotope abundance for environmental studies: a questionable approach 总被引:2,自引:0,他引:2
85.
Edwards CL 《Science (New York, N.Y.)》1910,32(824):502-504
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Previous work has identified two families of proteins that transport classical neurotransmitters into synaptic vesicles, but the protein responsible for vesicular transport of the principal excitatory transmitter glutamate has remained unknown. We demonstrate that a protein that is unrelated to any known neurotransmitter transporters and that was previously suggested to mediate the Na(+)-dependent uptake of inorganic phosphate across the plasma membrane transports glutamate into synaptic vesicles. In addition, we show that this vesicular glutamate transporter, VGLUT1, exhibits a conductance for chloride that is blocked by glutamate. 相似文献
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Kennett JP Houtz RE Andrews PB Edwards AR Gostin VA Hajos M Hampton MA Jenkins DG Margolis SV Ovenshine AT Perch-Nielsen K 《Science (New York, N.Y.)》1974,186(4159):144-147
Deep-sea drilling in the Southern Ocean south of Australia and New Zealand shows that the Circum-Antarctic Current developed about 30 million years ago in the middle to late Oligocene when final separation occurred between Antarctica and the continental South Tasman Rise. Australia had commenced drifting northward from Antarctica 20 million years before this. 相似文献
90.