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21.
22.
The methanol extract of Rumex nepalensis Spreng. roots at the oral dose of 100-400 mg/kg exhibited significant and dose-dependent purgative activity. 相似文献
23.
A new isoflavonol triglycoside, biochanin A 7-O-beta-D-apiofuranosyl-(1-->5)-beta-D-apiofuranosyl-(1-->6 )-beta-D- glucopyranoside (1), was isolated from Andira inermis roots in addition to the known compounds genistein 7-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside and lanceolarin. 相似文献
24.
Gunning RV Moores GD Jewess P Boyes AL Devonshire AL Khambay BP 《Pest management science》2007,63(6):569-575
It has been reported previously that the major resistance mechanism to pyrethroid insecticides by the cotton bollworm Helicoverpa armigera (Hübner) in Australia is a consequence of overproduction of esterase isoenzymes. This paper reports structure-activity relationships that support such a view, based on in vivo bioassays conducted with a range of pyrethroid structures containing a variety of acid and alcohol moieties and the correlation with in vitro esterase inhibition assays against the same structures, and identifies the critical regions of the molecule with regard to esterase inhibition, and hence resistance. The implications of this work in terms of possible resistance management are evaluated and discussed. 相似文献
25.
水土流失经济损失估算及环境经济学思考 总被引:12,自引:1,他引:12
<正>对环境价值或生态环境破坏的损失进行经济学量化,是完善环境管理政策,实行国民经济绿色核算,转变传统经济增长观,衡量是否把环境与经济真正纳入统一框架,实现可持续发展的重要基础性研究之一,目前也是一项研究的热点.除此之外,对水土流失经济损夫进行估算的直接意义还在于:正确估价水土流失的危害程度,引起决策者和公众的高度重视;改进水土保持工作方法,引进基于市场机制的经济管理手段,建立直接管制和经济激励相结合的政策体系.1 水土流失危害的环境经济学分析水上流失是在外营力作用下,土壤母质及其地面组成物质被破坏、剥蚀、转运和沉积的全过程.对水力侵蚀而言,外营力就是地表径流,地表径流在侵蚀土壤的同时,自己也流失了,即土和水的流失.水土流失发生的场所是土地,因此,水上流失的危害首先表现为土壤中的肥料损失、土地生产力的降低、土地资源的破坏和损失:除土地资源外,这些危害对土地经营者而言是一种实际的物质和价值损失,是生产者的私人成本.而当流失的水、土发生再分配时,就会淤积江河,缩短 相似文献
26.
Kurilich AC Jeffery EH Juvik JA Wallig MA Klein BP 《Journal of agricultural and food chemistry》2002,50(18):5053-5057
Antioxidant capacity of hydrophilic and lipophilic extracts from eight broccoli genotypes was compared using the oxygen radical absorbance capacity (ORAC) assay. Each genotype was analyzed for carotenoid, tocopherol, ascorbic acid, and flavonoid content. Results indicate that the antioxidant capacity of hydrophilic extracts ranged from 65.8 to 121.6 micromol trolox equivalents (TE)/g of tissue, and the capacity of lipophilic extracts ranged from 3.9 to 17.5 micromol TE/g. Ascorbic acid and flavonoid content of the hydrophilic extracts did not explain the total variation in antioxidant capacity of those extracts, suggesting either the presence of other antioxidant components that have yet to be identified or that the known antioxidants are producing synergistic effects. The carotenoids did correlate with antioxidant capacity of the lipophilic extracts and accounted for the majority of the variability in that fraction. The variability in hydrophilic and lipophilic antioxidant capacity found among these genotypes suggests that potential efficacy from antioxidants will vary considerably from genotype to genotype. 相似文献
27.
Amaral JS Alves MR Seabra RM Oliveira BP 《Journal of agricultural and food chemistry》2005,53(13):5467-5472
The tocopherol and tocotrienol composition of walnuts (Juglans regia L.) was determined for nine cultivars (cvs. Arco, Franquette, Hartley, Lara, Marbot, Mayette, Mellanaise, Parisienne, and Rego). Walnuts were harvested over three consecutive years from two different geographical origins (Bragan?a and Coimbra, Portugal), for a total of 26 samples. The methodology employed was a normal-phase high-performance liquid chromatography coupled to a series arrangement of a diode array detector followed by a fluorescence detector, allowing the simultaneous analysis of all tocopherols and tocotrienols. The analyses showed that all samples presented a similar qualitative profile composed of five compounds: alpha-tocopherol, beta-tocopherol, gamma-tocopherol, delta-tocopherol, and gamma-tocotrienol. gamma-Tocopherol was the major compound in all samples, ranging from 172.6 to 262.0 mg/kg, followed by alpha- and delta-tocopherols, ranging from 8.7 to 16.6 mg/kg and from 8.2 to 16.9 mg/kg, respectively. Multivariate analysis of the data obtained showed the existence of significant differences in composition among cultivars. These differences were also significant when cultivars were grouped by year of production, showing that besides genetic factors, the vitamin E composition was influenced by environmental factors. 相似文献
28.
Nihei K Ying BP Murakami T Matsuda H Hashimoto M Kubo I 《Journal of agricultural and food chemistry》2005,53(3):608-613
This is the first report for secondary metabolites in an African medicinal plant, Pachyelasma tessmannii (Leguminosae). Four novel saponins, pachyelasides A-D, were isolated from the methanol extract of the root bark by using recycling HPLC. These compounds showed molluscicidal activity (LD(50) < or =8.0 mug/mL) against the South American snail, Biomphalaria glabratus. The structures were determined on the basis of extensive nuclear magnetic resonance spectroscopic and matrix-assisted laser desorption/ionization time-of-flight mass spectrometric studies. 相似文献
29.
Three-Dimensional X-ray Microtomography 总被引:2,自引:0,他引:2
The new technique of x-ray microtomography nondestructively generates three-dimensional maps of the x-ray attenuation coefficient inside small samples with approximately 1 percent accuracy and with resolution approaching 1 micrometer. Spatially resolved elemental maps can be produced with synchrotron x-ray sources by scanning samples at energies just above and below characteristic atomic absorption edges. The system consists of a high-resolution imaging x-ray detector and high-speed algorithms for tomographic image reconstruction. The design and operation of the microtomography device are described, and tomographic images that illustrate its performance with both synchrotron and laboratory x-ray sources are presented. 相似文献
30.
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene 总被引:1,自引:0,他引:1
Elchebly M Payette P Michaliszyn E Cromlish W Collins S Loy AL Normandin D Cheng A Himms-Hagen J Chan CC Ramachandran C Gresser MJ Tremblay ML Kennedy BP 《Science (New York, N.Y.)》1999,283(5407):1544-1548
Protein tyrosine phosphatase-1B (PTP-1B) has been implicated in the negative regulation of insulin signaling. Disruption of the mouse homolog of the gene encoding PTP-1B yielded healthy mice that, in the fed state, had blood glucose concentrations that were slightly lower and concentrations of circulating insulin that were one-half those of their PTP-1B+/+ littermates. The enhanced insulin sensitivity of the PTP-1B-/- mice was also evident in glucose and insulin tolerance tests. The PTP-1B-/- mice showed increased phosphorylation of the insulin receptor in liver and muscle tissue after insulin injection in comparison to PTP-1B+/+ mice. On a high-fat diet, the PTP-1B-/- and PTP-1B+/- mice were resistant to weight gain and remained insulin sensitive, whereas the PTP-1B+/+ mice rapidly gained weight and became insulin resistant. These results demonstrate that PTP-1B has a major role in modulating both insulin sensitivity and fuel metabolism, thereby establishing it as a potential therapeutic target in the treatment of type 2 diabetes and obesity. 相似文献