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1.
2.
Bluegill absorbed 85% of 1 ppb of endrin from water within 48 hr under static exposure conditions. The absorbed radiocarbon was eliminated linearly with a half-life of about 4 weeks. Analyses of eliminated radioactivity revealed only conjugated metabolites. 12-anti-Hydroxyendrin and 12-syn-hydroxyendrin were tentatively identified by cochromatography using thin-layer chromatography/autoradiography and gas chromatography. These metabolites were also present as conjugates in the fish organs. Seventy-three percent of the absorbed radioactivity recovered from fish extracts was in the form of unchanged endrin. 相似文献
3.
Antonio Morello Yolanda Repetto Robert A. White Moises Agosin 《Pesticide biochemistry and physiology》1980,14(1):72-80
The metabolism of R-20458 [(E)-6,7-epoxy-1-(4-ethylphenoxy)-3,7-dimethyl-2-octene] by rat hepatocytes has been analyzed and compared with that of juvenile hormone I [methyl-(E,E)-cis-10,11-epoxy-7-ethyl-3,11-dimethyl-2,6-tridecadienoate] under identical conditions. The metabolism of R-20458 is characterized by the predominance of NADPH-dependent cytochrome P-450 and epoxide hydrolase reactions; whereas, JH I is metabolized mainly by carboxylesterase, epoxide hydrolase, and glutathione S-transferases. The metabolites of R-20458 have been shown to correspond to (E)-6,7-epoxy-1-(4-hydroxyethylphenoxy)-3,7-dimethyl-2-octene; (E)-6,7-epoxy-1-(4-acetylphenoxy)-3,7-dimethyl-2-octene; (E)-6,7-dihydroxy-1-(4-ethylphenoxy)-3,7-dimethyl-2-octene; and, (E)-6,7-dihydroxy-1-(4-acetylphenoxy)-3,7-dimethyl-2-octene. The production of the α-hydroxyethyl, p-acetylphenoxy, and acetylphenoxy-6,7-diol metabolites is markedly inhibited by SKF 525-A. No dramatic effects are produced by diethylmaleate and 1,2-epoxy-3,3,3-trichloropropane. 相似文献
4.
Twenty-seven compounds were screened as potential inhibitors of juvenile hormone esterases. Of these compounds O-ethyl-S-phenyl phosphoramidothiolate provided the best inhibition for the cabbage looper, Trichoplusia ni (Hubner), and the yellow mealworm, Tenebrio molitor L., while the juvenile hormone esterases of the house fly, Musca domestica L., were best inhibited by a juvenoid carbamate (1-(m-phenoxy-N-ethyl carbamate)-3,7-dimethyl-7-methoxy-2E-octene). The inhibition patterns of T. ni and T. molitor are similar, while those of M. domestica are relatively different. Further studies on the juvenile hormone and α-napthyl acetate esterases of T. ni showed that they could be differentially inhibited. Diisopropyl phosphorofluoridate and an alkyl trifluoromethyl ketone selectively inhibit the hydrolysis of α-naphthyl acetate and juvenile hormone, respectively, while O-ethyl-S-phenyl phosporamidothiolate inhibits both enzymes. The juvenile hormone esterases of T. ni also appear to be unique enzymes that are selective for juvenile-hormone-like molecules. The in vivo inhibition of T. ni juvenile hormone esterases by O-ethyl-S-phenyl phosphoramidothiolate slows the in vivo hydrolysis of juvenile hormone and results in delayed pupation and malformed larvae that resemble larval-pupal intermediates. Thus, the esterases involved in juvenile hormone metabolism appear to be important in juvenile hormone regulation. 相似文献
5.
Clemens Kötter 《Pesticide biochemistry and physiology》1978,9(3):263-267
Mitochondria were isolated from eggs of Spodoptera littoralis. With succinate (+pyruvate) as substrate, respiratory control ratios between 1.70 and 2.54 were obtained. Uncouplers and the energy transfer inhibitor oligomycin influenced these mitochondria in the well-known manner. The uncoupling activity of chlordimeform in vitro was very weak and decreased with increasing age of the eggs. Electron transport in mitochondria from chlordimeform-treated eggs was not uncoupled. Therefore, it is concluded that the ovicidal effect of this pesticide is not due to its uncoupling effect. 相似文献
6.
由于现代科学技术的飞速发展,现代信息技术及网络技术逐渐在温室环境控制中得到了应用,智能化温室在世界范围内引起了越来越广泛的关注,并在全世界范围内开始普及。为此,论述了通信及网络技术在温室环境自动控制中的应用情况,由此可以看出智能化温室给设施农业的发展带来的深远影响。 相似文献
7.
根据1998年2月至1999年5月在北部湾海域按季度进行的4个航次生态、环境综合调查资料,本文研究了北部湾海域浮游幼虫的主要类群及其季节变动。结果表明:北部湾海域浮游幼虫主要有15大类群;其中4类(长尾类幼虫、短尾类幼虫、口足类阿利玛幼虫、蛇尾类长腕幼虫)周年出现,其它为季节性出现。长尾类幼虫、口足类阿利玛幼虫、蛇尾类长腕幼虫、短尾类溞状幼虫、短尾类大眼幼虫及其它短尾类幼虫为优势类群。北部湾浮游幼虫的年丰度变化范围为0.02~7.65ind/m3,均值为0.50ind/m3,四季的丰度为夏季(0.86ind/m3)>春季(0.40ind/m3)>秋季(0.32ind/m3)>冬季(0.12ind/m3)。从春季到冬季整个浮游幼虫密集中心呈逆时针从湾的东北部向西北部海区移动,移至湾的中部后再返至西北部。K优势度曲线分析表明群落多样性由高到低依次为春季>冬季>夏季>秋季,总体上浮游幼虫群落多样性的季节差异不大。典范对应分析结果表明影响浮游幼虫栖息密度的主要因子是水温和pH,其次是盐度、溶解氧。 相似文献
8.
9.
At concentrations near 2 × 10?4M, barban, chlorpropham, and phenmedipham are inhibitors of the electron transfer in potato and mung bean mitochondria. The inhibition seems to be localized in the flavoprotein region. It affects preferentially the exogenous NADH dehydrogenation, in potato mitochondria (I50, 10?4M). Succinate dehydrogenation is less inhibited. At noninhibiting concentrations, the studied carbamates cannot uncouple the oxidative phosphorylations. Photosynthesis is completely inhibited by 2.10?7M phenmedipham, 5 × 10?5M barban, and 2 × 10?4M chlorpropham. The inhibition takes place at the PS II level. Moreover, barban and chlorpropham are uncouplers of the photophosphorylations for concentrations between 5 × 10?5 and 5 × 10?4M. The effects observed on mitochondrial respiration can also be found on respiration of Acer cultured cells. The effects on isolated chloroplast photosynthesis are also observed for slightly higher concentrations on cultured Chlorella and on pea and oat leaf fragments. 相似文献
10.
Membranes from house fly heads were tested for the presence of mucarinic acetylcholine receptors using as a probe [3H]quinuclidinyl benzilate ([3H]QNB). Based on the presence of saturable and reversible high-affinity binding of [3H]QNB, which is inhibited by muscarinic drugs, it is suggested that these sites may be muscarinic receptors. However, these putative muscarinic receptors differ in several characteristics from the ones in mammalian brain. They have lower affinities for muscarinic drugs and lower stereoselectivity, a relatively higher affinity for the nicotinic antagonist d-tubocurarine, a lower Hill coefficient for binding of muscarinic antagonists, and a lower concentration relative to α-bungarotoxin binding sites in the same membranes. Also, unlike mammalian muscarinic receptors, they are sensitive to treatments with N-ethylmaleimide and 5,5′-dithiobis(2-nitrobenzoic acid). The effect of reduction of disulfide bonds by dithiothreitol or mercaptoethanol suggests that only the insect receptor has one or more disulfide bonds which are important to binding. On the other hand, the putative muscarinic receptors of both insect and mammalian brains have important SH group(s), whose alkylation by p-chloromercuribenzoate inhibits binding. Also, chlorobenzilate is equally effective in inhibiting [3H]QNB binding to muscarinic putative receptors of house fly and bovine brains. 相似文献