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排序方式: 共有695条查询结果,搜索用时 15 毫秒
1.
目的 试图给出确定森林群落树种丰富度的方法,解决物种丰富度测度问题,完善森林生物多样性研究的方法。 方法 采用Monod模型表达种-面积曲线,通过数学手段确定最小森林群落面积和最大树种数。 结果 用本研究提出的方法对不同气候带森林物种丰富度进行测算,结果表明:热带森林群落具有更高的最大树种数和更大的群落最小面积,物种丰富度随气候带由热带到寒温带逐渐减少。 结论 用最大树种数能够确切表达不同气候带森林群落树种丰富度,克服了现有研究中直接把不同大小调查面积上的树种数量视为树种丰富度的弊端。  相似文献   
2.

Objective

To characterize the isoflurane-sparing effects of a high and a low dose of fentanyl in dogs, and its effects on mean arterial pressure (MAP) and heart rate (HR).

Study design

Prospective, randomized crossover trial.

Animals

Eight healthy male Beagle dogs weighing 12.1 ± 1.6 kg [mean ± standard deviation (SD)] and approximate age 1 year.

Methods

Dogs were anesthetized using isoflurane and minimum alveolar concentration (MAC) was determined in duplicate by the bracketing method using an electrical stimulus on the tarsus. Animals were administered fentanyl: low dose (33 μg kg?1 loading dose, 0.2 μg kg?1 minute?1) or high dose (102 μg kg?1 loading dose, 0.8 μg kg?1 minute?1) and MAC was re-determined (MACISO-F). Blood was collected for analysis of plasma fentanyl concentrations before administration and after MACISO-F determination. All values are presented as mean ± SD.

Results

Isoflurane MAC (MACISO) was 1.30 ± 0.23% in the low dose treatment, which significantly decreased to 0.75 ± 0.22% (average MAC reduction 42.3 ± 9.4%). MACISO was 1.30 ± 0.18% in the high dose treatment, which significantly decreased to 0.30 ± 0.11% (average MAC reduction 76.9 ± 7.4%). Mean fentanyl plasma concentrations were 6.2 and 29.5 ng mL?1 for low and high dose treatments, respectively. MAP increased significantly only in the high dose treatment (from 81 ± 8 to 92 ± 9 mmHg). HR decreased significantly in both treatments from 108 ± 25 to 61 ± 14 beats minute?1 with the low dose and from 95 ± 14 to 42 ± 4 beats minute?1 with the high dose.

Conclusions and clinical relevance

Fentanyl administration resulted in a dose-dependent isoflurane MAC-sparing effect with bradycardia at both doses and an increase in MAP only at high dose. Further evaluation is needed to determine the effects of fentanyl on the overall cardiovascular function.  相似文献   
3.
为筛选出对金黄色葡萄球菌(Staphylococcus aureus,S. aureus)和大肠杆菌(Escherichia coli,E. coli)具有良好抑菌作用的蒙药,试验采用打孔法测定S. aureusE. coli对石榴皮、诃子、小白蒿、黄芩、黄芪、苦参、铁线莲7味蒙药敏感程度,微量稀释法测定蒙药的最小抑菌浓度(minimal inhibitory concentration,MIC),棋盘法测定敏感蒙药对S. aureusE. coli的协同指数(fractional inhibitory concentration index,FICI)。结果显示:石榴皮、诃子、黄芩3味蒙药对S. aureus的抑菌圈直径为23.30~32.60 mm,MIC为0.98~7.80 mg/mL;石榴皮、诃子、黄芩3味蒙药对E. coli的抑菌圈直径为5.20~12.50 mm,MIC为7.80~31.50 mg/mL;石榴皮与诃子联合用药对S. aureus的FICI为1.00,为相加作用;诃子与黄芩、石榴皮分别联合用药对E. coli的FICI都为0.75,为相加作用。综上所述,石榴皮、诃子、黄芩3味蒙药对S. aureus综合抑菌效果达极度敏感或高度敏感;石榴皮、诃子、黄芩3味蒙药对E. coli综合抑菌效果达极度敏感或高度敏感;在抑制S. aureus的配方中石榴皮、黄芩、诃子可被优先考虑;在抑制E. coli的配方中黄芩、诃子、石榴皮可被优先考虑。  相似文献   
4.
ObjectiveTo determine the effect of remifentanil infusion on the minimum alveolar concentration of sevoflurane preventing movement (SEVOMACNM) and bispectral index (BIS) in dogs.Study designProspective, unmasked study.AnimalsA total of 10 adult Beagle dogs weighing 9.0 ± 1.1 kg.MethodsDogs were anesthetized with sevoflurane and baseline SEVOMACNM was determined. Remifentanil was infused at 5, 10 and 20 μg kg–1 hour–1, in sequence, with 20 minutes washout between infusions. Variables monitored throughout anesthesia included heart rate (HR), oscillometric blood pressure, end-tidal partial pressure of carbon dioxide, end-tidal sevoflurane concentration (Fe′Sevo) and BIS. SEVOMACNM after remifentanil infusion (SEVOMACNM-REMI) determination started 20 minutes after the start of each infusion. Venous blood samples were collected for plasma remifentanil concentration determination at baseline, SEVOMACNM-REMI determination time points, and 20 minutes after each infusion was stopped. A mixed model analysis was used to determine the effect of remifentanil infusion on response variables. The relationships between BIS and Fe′Sevo, plasma remifentanil concentrations and the percentage decrease in baseline SEVOMACNM were evaluated (p < 0.05).ResultsThe overall SEVOMACNM at baseline was 2.47 ± 0.11%. Addition of remifentanil at all infusion rates significantly decreased SEVOMACNM, but the medium and high doses resulted in significantly greater decreases in SEVOMACNM than the lower dose. There was no difference in SEVOMACNM percentage change between infusions 10 and 20 μg kg–1 hour–1. Plasma remifentanil concentrations were significantly different in all infusion rates. Baseline BIS value was 70 ± 1 and was lower than the BIS values recorded during all remifentanil infusions. BIS values were not significantly different among infusion rates. HR was lower and mean arterial pressure was higher during remifentanil infusions than at baseline.Conclusions and clinical relevanceAll remifentanil infusions decreased SEVOMACNM in dogs. Remifentanil infusion at any rate studied did not reduce BIS values.  相似文献   
5.
普宗朝  张山清 《草业科学》2021,38(1):110-121
基于新疆102个气象台站1961−2019年逐日平均气温、最低气温资料,采用统计学方法以及ArcGIS的空间插值技术,在对影响新疆紫花苜蓿种植的主要气候因子 ≥ 5 ℃积温、冬季最低气温时空变化特征分析的基础上,以80%保证率 ≥ 5 ℃积温和90%保证率冬季最低气温作为指标因子,研究了气候变暖背景下,新疆不同秋眠级紫...  相似文献   
6.

Objective

To determine the effect of oral trazodone on the minimum alveolar concentration (MAC) of isoflurane in dogs.

Study design

Prospective blinded, single-observer, randomized crossover experimental study.

Animals

Six adult (age 6.8 ± 1.6 months) healthy dogs (three males and three females), weighing 24.8 ± 3.4 kg (mean ± standard deviation).

Methods

Each dog was anesthetized twice with a minimum of 7 days between anesthetic episodes. Dogs were randomly assigned to be administered two treatments in a crossover design: premedication with trazodone (8 mg kg?1; TRAZ–ISO) orally 2 hours prior to an anesthetic episode or no (ISO). Dogs were anesthetized with intravenous propofol (6 mg kg?1) and isoflurane in >95% oxygen. Isoflurane MAC was determined using an iterative bracketing technique with electrodes placed in the buccal mucosa. Hemodynamic variables were compared at the lowest end-tidal isoflurane concentration at which each dog did not respond. A paired t test was used to assess the effect of treatment on outcome variables with significance set to a value of p < 0.05.

Results

The MAC concentration (mean ± standard deviation) in dogs administered TRAZ–ISO was 0.85 ± 0.17% compared with 1.02 ± 0.11% in those administered ISO (p = 0.01, 95% confidence interval ?0.25 to ?0.05), resulting in a mean MAC reduction of 17 ± 12%. There were no differences in hemodynamic variables between treatments.

Conclusions and clinical relevance

Premedication of dogs with oral trazodone (8 mg kg?1) 2 hours prior to anesthetic induction has a significant isoflurane MAC sparing effect with no significant observed hemodynamic benefit.  相似文献   
7.
猪传染病的发生给养猪业的发展带来了严重的损失,造成了很大危害。为实时掌握天水市二三类猪传染病的发生和流行情况,为今后有效防控猪传染病提供科学依据,近两年天水市采用ELISA、平板凝集、免疫胶体金技术和细菌染色等检测方法进行了猪传染病调查,基本确定了近两年主要猪传染病的发生情况。在此基础上,论文运用生物统计学方法结合Excell建立了一种计算最小调查样本量的简便方法,确定了调查精度达到95%,至少发现1个阳性猪传染病例所需要的最小样本量,然后运用该计算方法计算出了天水市猪传染病调查所需要的最小样本量。  相似文献   
8.
ObjectiveTo test whether naltrexone, an opioid receptor antagonist, affects the minimum alveolar concentration (MAC) of isoflurane in cats, a species that is relatively resistant to the general anesthetic sparing effects of most opioids.Study designRandomized, crossover, placebo-controlled, blinded experimental design.AnimalsSix healthy adult cats weighing 4.9 ± 0.7 kg.MethodsThe cats were studied twice. In the first study, baseline isoflurane MAC was measured in duplicate. The drug (saline control or 0.6 mg kg?1 naltrexone) was administered IV every 40–60 minutes, and isoflurane MAC was re-measured. In the second study, cats received the second drug treatment using identical methods 2 weeks later.ResultsIsoflurane MAC was 2.03 ± 0.12% and was unchanged from baseline following saline or naltrexone administration.Conclusion and clinical relevanceMinimum alveolar concentration was unaffected by naltrexone. Because MAC in cats is unaffected by at least some mu-opioid agonists and antagonists, spinal neurons that are directly modulated by mu-opioid receptors in this species cannot be the neuroanatomic sites responsible for immobility from inhaled anesthetics.  相似文献   
9.
OBJECTIVE: To determine the cardiopulmonary effects of desflurane (DES) in horses. ANIMALS: Six healthy adult horses, three males and three females, aged 9 +/- 4 (mean +/- SD) years and weighing 370 +/- 36 kg. MATERIALS AND METHODS: Anaesthesia was induced with an O2 (10 L minute(-1)) and DES mixture (vaporizer setting 18%). After oro-tracheal intubation, horses were positioned in right lateral recumbency. Anaesthesia was maintained with DES in O2 (20 mL kg(-1) minute(-1)) delivered through a large animal circle breathing system. The minimum alveolar concentration of DES (MAC(DES)) that prevented purposeful movement in response to 60 seconds of electrical stimulation of the oral mucous membranes was determined for each horse. The delivered concentration of DES was then increased to achieve end-tidal concentrations corresponding to 1.5 x MAC(DES), 1.75 x MAC(DES), and 2.0 x MAC(DES). Heart rate (HR), mean arterial blood pressure (MAP), respiratory rate (fr), tidal volume (VT), minute volume (VM) and core temperature were determined, and blood samples for arterial blood gas analysis taken at each DES concentration. All data were analysed by two-way anova for repeated measures and Fisher's test for multiple comparisons. A probability level of p < 0.05 was applied. RESULTS: Desflurane concentrations of 2.0 x MAC(DES) increased HR whereas lower concentrations did not. Mean arterial pressure was not affected by 1.0 x MAC(DES) 1.5 x MAC(DES) or 1.75 x MAC(DES), whereas it decreased at 2.0 x MAC(DES). All concentrations of DES examined significantly depressed fr, VT and VM. CONCLUSIONS AND CLINICAL RELEVANCE: Desflurane concentrations between 1.0 and 1.75 x MAC(DES) reduces fr and VM but does not affect HR or MAP in horses.  相似文献   
10.

Objective

To determine the effects of low and high dose infusions of dexmedetomidine and a peripheral α2-adrenoceptor antagonist, MK-467, on sevoflurane minimum alveolar concentration (MAC) in dogs.

Study design

Crossover experimental study.

Animals

Six healthy, adult Beagle dogs weighing 12.6 ± 0.9 kg (mean ± standard deviation).

Methods

Dogs were anesthetized with sevoflurane in oxygen. After a 60-minute instrumentation and equilibration period, the MAC of sevoflurane was determined in triplicate using the tail clamp technique. PaCO2 and temperature were maintained at 40 ± 5 mmHg (5.3 ± 0.7 kPa) and 38 ± 0.5 ºC, respectively. After baseline MAC determination, dogs were administered two incremental loading and infusion doses of either dexmedetomidine (1.5 μg kg?1 then 1.5 μg kg?1 hour?1 and 4.5 μg kg?1 then 4.5 μg kg?1 hour?1) or MK-467 (90 μg kg?1 then 90 μg kg?1 hour?1 and 180 μg kg?1 then 180 μg kg?1 hour?1); loading doses were administered over 10 minutes. MAC was redetermined in duplicate starting 30 minutes after the start of drug administration at each dose. End-tidal sevoflurane concentrations were corrected for calibration and adjusted to sea level. A repeated-measures analysis was performed and comparisons between doses were conducted using Tukey's method. Statistical significance was considered at p < 0.05.

Results

Sevoflurane MAC decreased significantly from 1.86 ± 0.3% to 1.04 ± 0.1% and 0.57 ± 0.1% with incremental doses of dexmedetomidine. Sevoflurane MAC significantly increased with high dose MK-467, from 1.93 ± 0.3% to 2.29 ± 0.5%.

Conclusions and clinical relevance

Dexmedetomidine caused a dose-dependent decrease in sevoflurane MAC, whereas MK-467 caused an increase in MAC at the higher infusion dose. Further studies evaluating the combined effects of dexmedetomidine and MK-467 on MAC and cardiovascular function may elucidate potential benefits of the addition of a peripheral α2-adrenergic antagonist to inhalation anesthesia in dogs.  相似文献   
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